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Characterization of PEG-Modified Composite Membranes for Microfluidic Oxygenator Applications

Abstract Microfluidic oxygenators promise to advance extracorporeal membrane oxygenation (ECMO) devices with enhanced hemodynamics and low prime volume. We are developing a silicon-based membrane oxygenator that will offer improved gas..

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Risk of Developing Lower Limb Ischemia in Patients With Extracorporeal Cardiopulmonary Resuscitation: A Secondary Analysis of the Study of Advanced…

Abstract Objectives:  While potential risks for limb ischemia have been explored in studies of venoarterial extracorporeal membrane oxygenation (ECMO), they remain inadequately defined for patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR)...

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Role of Venoarterial Extracorporeal Membrane Oxygenation as a Procedural Support Tool in Cardiovascular Instability: A Case Series

Abstract The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasing worldwide. Patients with cardiogenic shock were the first indication for VA-ECMO according to the Extracorporeal Life Support Organization (ELSO)..

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Venopulmonary extracorporeal life support: An Extracorporeal Life Support Organization registry analysis

Abstract Background There is a paucity of data informing on the current use, adverse events, outcomes, and prognostic drivers for patients receiving venopulmonary extracorporeal life support (VP ECLS). We aimed..

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Impact of different blood flow modes on hemodynamic environment, thrombosis risk and oxygen transport of oxygenators: A numerical simulation study

Abstract Background and Objective Pulsatile blood flow is considered more potential for delivering hemodynamic energy and enhancing microcirculatory perfusion in patients compared to non-pulsatile flow in ECMO. This study aims..

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Outcomes after postcardiotomy venoarterial extracorporeal membrane oxygenation in young patients: An individual patient data meta-analysis

Abstract Objective We aimed to evaluate the early and midterm mortality of young patients treated for cardiogenic shock with venoarterial extracorporeal membrane oxygenation (VA-ECMO) after adult cardiac surgery. Methods Studies..

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Healthcare professionals’ views on training, standards, and resources for extracorporeal membrane oxygenation: a cross-sectional survey

Abstract Aim To assess health care professionals’ knowledge and opinions regarding extracorporeal membrane oxygenation (ECMO) use, training, standards, and resource availability. Methods This cross-sectional study employed an online self-administered survey..

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Incidence and Risk Factors of Limb Ischaemia in Adult Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis

Abstract Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become an essential life-saving therapy for patients with refractory cardiogenic shock, cardiac arrest, and severe cardiopulmonary failure. Despite its expanding use and..

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The comparison of circuit lifespan between integration and separation approach in extracorporeal membrane oxygenation patients requiring continuous renal replacement therapy…

Abstract Background: The estimated incidence of acute kidney injury requiring renal replacement therapy (RRT), mainly continuous RRT (CRRT), in patients necessitating extracorporeal membrane oxygenation (ECMO) is approximately 50%. Currently, two..

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Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model

Abstract Hydrogen has emerged as a therapeutic agent in inflammatory critical illnesses due to its potential to modulate inflammation and oxidative stress. However, its role in extracorporeal membrane oxygenation (ECMO),..

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Breaking the Rhythm: Extracorporeal Membrane Oxygenation (ECMO) as a Life Saver in a Case of Resistant Arrhythmia and Cardiac Arrest

Abstract Refractory ventricular arrhythmias and cardiac arrest in younger patients are rare, life-threatening events, particularly when standard resuscitation fails. Extracorporeal membrane oxygenation (ECMO) provides temporary circulatory support, enabling hemodynamic stabilization,..

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Viscoelastic Testing to Guide Anticoagulation During Extracorporeal Membrane Oxygenation in Lung Transplantation

Abstract Extracorporeal membrane oxygenation (ECMO) represents an established modality of intraoperative circulatory and respiratory support during lung transplantation (LTx). Systemic anticoagulation with unfractionated heparin (UFH) remains essential to prevent circuit..

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Outcomes in Patients Requiring VENO-Venous Extracorporeal Membrane Oxygenation After Cardiac Surgery: An Analysis From the PELS-1 Study

Abstract Background Acute respiratory failure after cardiac surgery is an uncommon complication, affecting morbidity and mortality. In these patients, respiratory extracorporeal membrane oxygenation (ECMO) support may be beneficial, as it..

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Implementation of emergency extracorporeal membrane oxygenation in a hospital without on-site cardiothoracic surgery support

Abstract Introduction Extracorporeal cardiopulmonary resuscitation (ECPR) using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a treatment option for refractory cardiac arrest patients, but it has mostly been restricted to hospitals with..

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Extracorporeal Membrane Oxygenation Related Axillary Artery Cannulation and Aortic Hemodynamics: Insights From Computational Fluid Dynamics

Abstract Axillary and subclavian artery cannulation for veno-arterial extracorporeal membrane oxygenation (V-A ECMO) offers clinical advantages but introduces complex flow dynamics within the aortic arch. This study employed patient-specific computational..

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Extracorporeal Membrane Oxygenation Discontinuation Due to Resource Limitations

Abstract To examine the global epidemiology of extracorporeal membrane oxygenation discontinuation due to resource limitation (EDRL), assessing differences across geographic regions and between pre- and post-coronavirus disease 2019 (COVID-19) periods...

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Challenges of ECMO use for severe trauma: a narrative review

Abstract Background Patients with severe trauma are at high risk of developing life-threatening complications, including acute respiratory failure and circulatory collapse. Extracorporeal membrane oxygenation (ECMO) offers critical support when conventional..

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Ultrasound in Extracorporeal Membrane Oxygenation: An ELSO State-of-the-Art Review

Abstract Ultrasound has become indispensable in the management of patients supported with extracorporeal membrane oxygenation (ECMO), enabling rapid diagnosis, procedural guidance, physiologic monitoring, and informed decision-making across the entire ECMO..

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When stopping is just as important as starting: the challenge of extracorporeal membrane oxygenation

Abstract Extracorporeal life support (ECLS) is a high-risk, high-cost intervention that often entails prolonged ICU and hospital stays. Its rapid evolution raises crucial questions of appropriateness, proportionality, and value. Whereas..

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Early mechanical reperfusion in high-risk pulmonary embolism supported by V-A ECMO: a multicenter international cohort study

Abstract Objectives To explore how early mechanical reperfusion impacts outcomes in high-risk pulmonary embolism (PE) patients supported by veno-arterial extracorporeal membrane oxygenation (V-A ECMO). Methods This retrospective international study included..

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Conversion From Venovenous to Venoarterial or Hybrid Extracorporeal Membrane Oxygenation: Analysis From the Extracorporeal Life Support Organization Registry

Abstract Objectives:  Venovenous extracorporeal membrane oxygenation (ECMO) represents a standard and well-accepted modality of treating patients with refractory respiratory failure. Nevertheless, some patients might develop refractory hypoxemia, hemodynamic compromise or..

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Effect of prone positioning on pathophysiology and lung histopathology during VV-ECMO in severe ARDS: an experimental animal study

Abstract Background: Prone positioning improves survival in patients with acute respiratory distress syndrome (ARDS) by reducing ventilator-induced lung injury and enhancing ventilation–perfusion matching. Whether these physiological benefits translate to patients..

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Investigating biomarkers associated with mortality in patients receiving VA-ECMO for cardiogenic shock: a systematic review

Abstract Context: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-sustaining therapy for severe refractory cardiogenic shock. Although VA-ECMO provides various degrees of cardiopulmonary support, mortality rates remain high. Serum biomarkers have..

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A consensus of international experts on definition, sampling, treatment, and prevention of peripheral extracorporeal membrane oxygenation cannula-site infection obtained by…

Abstract Background: Nosocomial infections are common in patients receiving extracorporeal membrane oxygenation (ECMO), with ECMO cannula‑site infections (ECMO‑CSI) being the most frequent infections directly related to the ECMO run. These..

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The importance of early veno-arterial extracorporeal membrane oxygenation in the management of amniotic fluid embolism complicated by cardiac arrest: a…

Abstract Background Amniotic fluid embolism (AFE) with cardiac arrest is an obstetric emergency with an exceedingly high maternal mortality. Early application of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may provide essential..

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A Contemporary Guide of Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock

Abstract Managing refractory cardiogenic shock is individualized, with few aspects considered routine or universally contraindicated. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a temporary mechanical circulatory support strategy, providing hemodynamic stabilization..

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Incidence of Healthcare-Associated Infections in Patients on Extracorporeal Membrane Oxygenation Secondary to Respiratory or Cardiac Failure: A Retrospective Cohort Study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life support technique used in patients with respiratory or cardiac failure. Despite the increased use of ECMO, the incidence and risk factors..

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Increasing Anticoagulation Intensity in the Oxygenator During Flow Reduction Trials in Venoarterial Extracorporeal Membrane Oxygenation

Abstract Anticoagulation is mandatory during venoarterial extracorporeal membrane oxygenation (V-A ECMO) flow reduction trials with very low blood flow. Anticoagulation in the ECMO circuit might be intensified with less effect..

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Training of Emergency Medicine Residents to Initiate Extracorporeal Membrane Oxygenation Cardiopulmonary Resuscitation (ECPR)

Abstract Background The objective of our study was to evaluate the ability of Emergency Medicine (EM) physicians who have completed an accelerated extracorporeal membrane oxygenation (ECMO) course and mannequin training..

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Predictors of VV-ECMO weaning safety: longitudinal ventilatory ratio assessment during sweep gas off trials, a retrospective cohort study

Abstract Background Separation from venovenous extracorporeal membrane oxygenation (VV-ECMO) is a pivotal transition for patients with acute respiratory distress syndrome (ARDS). Impaired alveolar ventilation more so than oxygenation may be..

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