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Chronic kidney disease in congenital heart disease patients: a narrative review of evidence

Abstract Purpose of review Patients with congenital heart disease have a number of risk factors for the development of chronic kidney disease (CKD). It is well known that CKD has..

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Utility of a modified vascular corrosion casting technique in the diagnosis of fetal total anomalous pulmonary venous connection

Abstract Total anomalous pulmonary venous connection (TAPVC) is a rare congenital cardiac malformation, and prenatal detection of TAPVC malformation remains a challenging. TAPVC can be easily missed or misdiagnosed in..

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Diagnosis, management and therapeutic strategies for congenital long QT syndrome

Abstract Congenital long QT syndrome (LQTS) is characterised by heart rate corrected QT interval prolongation and life-threatening arrhythmias, leading to syncope and sudden death. Variations in genes encoding for cardiac..

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Effect of perfusate oxygenation on inflammatory response in congenital heart disease children from low versus high altitude

Abstract Objective To examine the altitude differences in the optimal perfusate oxygenation (PpO2) in patients who underwent cardiac surgery. Methods We included children (aged 1 month to 18 years) with  surgically repaired between..

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Robotic Surgery in the Adult Congenital Cardiac Patient: Back to the Future?

Abstract In the early years of 2000, a growing enthusiasm toward robotic and minimally invasive techniques became more prevalent in the field of cardiac surgery. Robotically assisted surgical systems were..

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The Inverse Relationship Between Endothelium-Dependent Vasodilation and Blood Pressure is Lost After Cardiopulmonary Bypass

Abstract Cardiopulmonary bypass (CPB) is required for the surgical correction of congenital heart defects and incites an acute inflammatory response that impairs endothelial function post-operatively. Therefore, we hypothesized that the..

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Fetal circulation

The blood that flows through the fetus is actually more complicated than after the baby is born (). This is because the mother (the placenta) is doing the work that..

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mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease

Take Home Points: modified Dixon (mDixon) 3D cardiovascular magnetic resonance angiography (CMRA) demonstrates reduced artefact burden and better delineation of head and neck vessels as well as pulmonary veins compared..

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Lessons Learned From the First Pilot Study of the Compensatory Reserve Index After Congenital Heart Surgery Requiring Cardiopulmonary Bypass

Abstract Background: Early warning systems that utilize dense physiologic data and machine learning may aid prediction of decompensation after congenital heart surgery (CHS). The Compensatory Reserve Index (CRI) analyzes changing..

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Infective Endocarditis in Childhood: a Single- Center Experience of 18 Years

Abstract Introduction: We aimed to present the risk factors, clinical and laboratory findings, treatment management, and risk factors for morbidity and mortality of infective endocarditis (IE) as well as to relate..

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2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease Network…

Abstract This is an updated, comprehensive and practical guideline for healthcare providers providing care to children and young adults with pulmonary hypertension (PH) and pulmonary vascular disease (PVD). Methodology included..

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Management of Neonates With Tetralogy of Fallot

  Study Questions: What are the differences in outcomes between a strategy of staged repair (SR) (initial palliation [IP] and subsequent complete repair [CR]) as compared with primary repair (PR)..

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Simple equations to predict the effects of veno‐venous ECMO in decompensated Eisenmenger syndrome

Abstract Adult patients with uncorrected congenital heart diseases and chronic intracardiac shunt may develop Eisenmenger syndrome (ES) due to progressive increase of pulmonary vascular resistance, with significant morbidity and mortality...

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Updating an Empirically Based Tool for Analyzing Congenital Heart Surgery Mortality

Abstract Objectives: STAT Mortality Categories (developed 2009) stratify congenital heart surgery procedures into groups of increasing mortality risk to characterize case mix of congenital heart surgery providers. This update of..

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Effect of retrograde autologous priming based on miniaturized cardiopulmonary bypass in children undergoing open heart surgery

Abstract To evaluate the effectiveness of retrograde autologous priming (RAP) based on miniaturized cardiopulmonary bypass (CPB) circuit in children undergoing open heart surgery. We performed a retrospective analysis of all..

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Impact of miniaturized cardiopulmonary bypass circuits on ultrafiltration during congenital heart surgery

Abstract   Objective: To investigate whether the miniaturized cardiopulmonary bypass (CPB) system decreased the usage of ultrafiltration (UF), and to explore whether the non-UF with miniaturized CPB strategy could get..

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Effect of acid–base balance on postoperative course in children with hypoplastic left heart syndrome after the modified Norwood procedure

Abstract Hypoplastic left heart syndrome (HLHS) is a congenital heart defect that requires 3-stage cardiac surgical treatment and multidirectional specialist care. The condition of newborns in the first postoperative days..

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The “basic” approach: a single-centre experience with a cost-reducing model for paediatric cardiac extracorporeal membrane oxygenation

Abstract OBJECTIVES:  Extracorporeal membrane oxygenation (ECMO) is a lifesaving but expensive therapy in terms of financial, technical and human resources. We report our experience with a ‘basic’ ECMO support model,..

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Topical and low-dose intravenous tranexamic acid in cyanotic cardiac surgery

Abstract Background Coagulopathy is a major problem in surgery for cyanotic congenital heart disease. Tranexamic acid has been used both topically and systemically and plays a vital role in pediatric..

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Results of Extracorporeal Cardiopulmonary Resuscitation in Children

Abstract Background Survival of children experiencing cardiac arrest refractory to conventional cardiopulmonary resuscitation (CPR) is very poor. We sought to examine current era outcomes of extracorporeal CPR (ECPR) support for..

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S100 and S100β: biomarkers of cerebral damage in cardiac surgery with or without the use of cardiopulmonary bypass

Abstract Objective The present study is to describe the clinical impact of S100 and S100β for the evaluation of cerebral damage in cardiac surgery with or without the use of..

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Extended use of cardiopulmonary bypass in a multidisciplinary hospital

Abstract Objective To share our experience highlighting the additional use of cardiopulmonary bypass (CPB) in cases other than the conventional ischemic, congenital and valvular heart diseases. Methodology All patients undergoing..

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Venous Cannulation for Cardiopulmonary Bypass in the Case of Anomaly of the Inferior Vena Cava

Abstract  of the  and its tributaries are quite uncommon; however, since the development of , they have been described more frequently. Most of them are usually asymptomatic, although they can have clinical..

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Maternal obesity and excessive maternal weight gain during pregnancy: effects on outcomes after neonatal cardiac surgical procedures

Abstract Introduction Maternal obesity is associated with an increased risk for adverse perinatal outcomes. Obesity is also associated with a chronic inflammatory state and metabolic derangements that affect the newborn...

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Postcardiotomy refractory ventricular fibrillation: rescue using veno-arterial extracorporeal membrane oxygenation

Abstract We present a case of 7-hour ventricular fibrillation with successful use of veno-arterial extracorporeal membrane oxygenation as a bridge to recovery in a 30-year-old patient with grown-up congenital heart..

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Haem is associated with thrombosis in neonates and infants undergoing cardiac surgery for congenital heart disease

Abstract Background Haem levels are associated with thrombosis in a variety of diseases, as well as being a contributing cause of thrombotic events in animal models. Materials and Methods We..

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Empirical Vancomycin Dosing in Pediatric Patients with Congenital Heart Disease and the Impact of Cardiopulmonary Bypass on Trough Concentrations

Abstract Objectives To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and to examine the impact of cardiopulmonary bypass..

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Utility of Sonoclot in Prediction of Postoperative Bleeding in Pediatric Patients Undergoing Cardiac Surgery for Congenital Cyanotic Heart Disease: A…

Abstract Objectives To assess the utility of Sonoclot in prediction of  in pediatric patients undergoing cardiac surgery with  for . Design Prospective, . Setting Single university hospital. Participants Eighty-seven pediatric patients undergoing cardiac surgery..

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Ninety-two days of extracorporeal membrane oxygenation support following congenital heart surgery

Abstract We report on a case involving a 10-month-old infant who received prolonged ECMO therapy following cardiac surgery for multiple ventricular septal defects (VSD). The patient was successfully weaned from..

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Perioperative Near-Infrared Spectroscopy Monitoring in Neonates With Congenital Heart Disease: Relationship of Cerebral Tissue Oxygenation Index Variability With Neurodevelopmental Outcome

Abstract Objectives:  To evaluate the value of perioperative cerebral near-infrared spectroscopy monitoring using variability analysis in the prediction of neurodevelopmental outcomes in neonates undergoing surgery for congenital heart disease. Design: ..

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