Archives

thumbnail
0 comment

A Randomized Clinical Trial of Perfusion Modalities in Pediatric Congenital Heart Surgery Patients

Abstract Background The objective of this randomized clinical trial was to investigate the effects of perfusion modalities on cerebral hemodynamics, vital organ injury, quantified by the Pediatric Logistic Organ Dysfunction-2..

Read More
thumbnail
0 comment

The myocardial protective effects of adenosine pretreatment in children undergoing cardiac surgery: a randomized controlled clinical trial

Abstract Objective: Adenosine pretreatment reduces injury caused by ischemia-reperfusion. To investigate the hypothesis that adenosine pretreatment would modulate injury induced by cardiopulmonary bypass (CPB) and myocardial ischemia/reperfusion, we conducted a randomized..

Read More
thumbnail
0 comment

Young adults after arterial switch operation for transposition of the great arteries in Switzerland: a growing population

Abstract Background: Adults with transposition of the great arteries (d-TGA) after the arterial switch operation (ASO) are an evolving cohort in adult cardiology. We aimed to analyze cardiac function and cardiac..

Read More
thumbnail
0 comment

S100B in cardiac surgery brain monitoring: friend or foe?

Abstract Recent advances in perioperative management of adult and pediatric patients requiring open heart surgery (OHS) and cardiopulmonary bypass (CPB) for cardiac and/or congenital heart diseases repair allowed a significant..

Read More
thumbnail
0 comment

Effect of CPB Glucose Levels on Inflammatory Response After Pediatric Cardiac Surgery

Abstract Background: Systemic inflammatory response syndrome (SIRS) is a common complication after cardiac surgery. There are no definite optimal glycemic threshold for pediatric patients receiving open-heart surgery with CPB. The..

Read More
thumbnail
0 comment

Antithrombin III infusion improves anticoagulation in congenital diaphragmatic hernia patients on extracorporeal membrane oxygenation

Abstract Purpose Achieving effective anticoagulation during neonatal extracorporeal membrane oxygenation (ECMO) without increasing the risk of hemorrhage remains challenging. The use of antithrombin III (AT-III) for this purpose has been..

Read More
thumbnail
0 comment

Does severe hyperlactatemia during cardiopulmonary bypass predict a worse outcome?

Abstract Introduction The aim of the current study was to evaluate the impact of increased blood lactate levels during cardiopulmonary bypass (CPB) on immediate results in patients who underwent open..

Read More
thumbnail
0 comment

Near-infrared spectroscopy for perioperative assessment and neonatal interventions

Abstract Perioperative applications of near-infrared spectroscopy (NIRS) to monitor regional tissue oxygenation and perfusion in cardiac and noncardiac surgery are of increasing interest in neonatal care. Complex neonatal surgery can..

Read More
thumbnail
0 comment

How Dose Body Water Composition Change Around Cardiopulmonary Bypass Surgery of Children with Congenital Heart Disease? -Assessing by Bioelectrical Impedance…

Abstract Introduction: Although the management of body water balance on cardiac surgery with cardiopulmonary bypass (CPB), especially in children, is essential, little is known how body water composition changes around CPB...

Read More
thumbnail
0 comment

Vasoplegic syndrome after cardiovascular surgery: A review of pathophysiology and outcome-oriented therapeutic management

Abstract Background: Vasoplegic syndrome (VPS) is defined as systemic hypotension due to profound vasodilatation and loss of systemic vascular resistance (SVR), despite normal or increased cardiac index, and characterized by..

Read More
thumbnail
0 comment

The Anesthesiologist’s Perspective and Experience in Global Congenital Cardiac Surgery: Results of a Survey of the Congenital Cardiac Anesthesia Society…

Abstract Anesthesiologists are important components of volunteer teams which perform congenital cardiac surgery in low-resource settings throughout the world, but limited data exist to characterize the nature and breadth of..

Read More
thumbnail
0 comment

Protamine-Induced Coronary Graft Thrombosis: A Review

Abstract Perioperative myocardial infarction is a serious complication affecting a significant portion of patients undergoing coronary artery bypass graft surgery. This may arise due to coronary graft thrombosis, a rare..

Read More
thumbnail
0 comment

Ex Vivo Allograft Perfusion for Complex Pediatric Heart Transplant Recipients

Abstract Background Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo allograft perfusion with the..

Read More
thumbnail
0 comment

Spectrum Medical Quantum or Terumo CDI 500: Which Device Measures Hemoglobin and Oxygen Saturation Most Accurately When Compared to a…

Abstract To examine the accuracy between analyzers, the Terumo CDI 500 and the Spectrum Medical Quantum were compared to each other and to the ABL90 FLEX benchtop blood analyzer. Patients..

Read More
thumbnail
0 comment

Education of Children With Cyanotic Congenital Heart Disease After Neonatal Cardiac Surgery

Abstract Background The aim of the study was to evaluate the educational achievement of patients diagnosed with  physiology (UVHP) or transposition of the  (TGA) after neonatal cardiac surgery. Methods An exploratory online..

Read More
thumbnail
0 comment

Impact of Corticosteroids on Cardiopulmonary Bypass Induced Inflammation in Children: A Meta-Analysis

Abstract Background Corticosteroids suppress the inflammatory response to  in children undergoing cardiac surgery. What is less clear is the impact of corticosteroids on the postoperative course. Methods A systematic review and..

Read More
thumbnail
0 comment

Postoperative Hematocrit and Adverse Outcomes in Pediatric Cardiac Surgery Patients: A Cross-Sectional Study From the Society of Thoracic Surgeons and…

Abstract BACKGROUND:  We sought to examine potential associations between pediatric postcardiac surgical hematocrit values and postoperative complications or mortality. METHODS:  A retrospective, cross-sectional study from the Society of Thoracic Surgeons..

Read More
thumbnail
0 comment

Interrelations of Intraoperative Changes in Cerebral Tissue Oxygen Saturation with Brain Volumes and Neurodevelopment Outcome After the Comprehensive Stage II…

Abstract Objectives The monitoring of cerebral tissue oxygen saturation by near-infrared spectroscopy (ScerebO2) is used widely in pediatric cardiac anesthesia. However, little information is available on the effects of changes..

Read More
thumbnail
0 comment

Risk Factors of Venoarterial Extracorporeal Membrane Oxygenation–Related Intracranial Hemorrhage in Children with Congenital Heart Disease

Abstract To analyze the risk factors for intracranial hemorrhage (ICH) in congenital heart disease (CHD) patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO). We performed a retrospective analysis of VA ECMO patients..

Read More
thumbnail
0 comment

Impact of Cardiopulmonary Bypass on Neurogenesis and Cortical Maturation

Abstract Objective Neurodevelopmental delays and frontal lobe cortical dysmaturation are widespread among children with congenital heart disease (CHD). The subventricular zone (SVZ) is the largest pool of neural stem/progenitor cells..

Read More
thumbnail
0 comment

Reduced Systemic Nitric Oxide Bioavailability Parallels Microvascular Endothelial Dysfunction during Cardiopulmonary Bypass

Abstract Introduction Cardiopulmonary bypass (CPB) is currently performed in infants and newborns for surgical correction of congenital heart diseases (CHDs).1 CPB exposes the body to extreme, nonphysiologic conditions that initiate a..

Read More
thumbnail
0 comment

Early biochemical markers in the assessment of acute kidney injury in children after cardiac surgery

Abstract Our aim was to evaluate biochemical markers in plasma (NGAL, CysC) and urine (NGAL, KIM-1) in children's early onset of acute kidney injury after congenital heart defect surgery using..

Read More
thumbnail
0 comment

Support with extracorporeal membrane oxygenation for over 1 year duration as a bridge to cardiac transplantation: a case report and…

Abstract We present the case of a 13-year-old male with a complex congenital cardiac history who was supported with extracorporeal membrane oxygenation for 394 days while awaiting cardiac transplantation. The..

Read More
thumbnail
0 comment

Methylprednisolone Plasma Concentrations During Cardiac Surgery With Cardiopulmonary Bypass in Pediatric Patients

Abstract Introduction: To our knowledge, methylprednisolone pharmacokinetics and plasma concentrations have not been comprehensively investigated in children with congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass. It is unknown whether..

Read More
thumbnail
0 comment

Timing of congenital cardiac surgery in children who turned COVID-19 positive

Abstract We report a series of four patients with CHD who tested positive for COVID-19, got treated, and underwent cardiac surgery in the same sitting. All had an uneventful perioperative..

Read More
thumbnail
0 comment

Safety and utility of modified ultrafiltration in pediatric cardiac surgery

Abstract Introduction: Modified ultrafiltration (MUF) is employed at the termination of cardiopulmonary bypass (CPB) in pediatric and neonatal patients undergoing congenital heart surgery to reduce the accumulation of total body..

Read More
thumbnail
0 comment

Atrial septal defect in adulthood: a new paradigm for congenital heart disease

Abstract Atrial septal defects (ASDs) represent the most common congenital heart defect diagnosed in adulthood. Although considered a simple defect, challenges in optimal diagnostic and treatment options still exist due..

Read More
thumbnail
0 comment

Early motor outcomes in infants with critical congenital heart disease are related to neonatal brain development and brain injury

Abstract Aim To assess the relationship between neonatal brain development and injury with early motor outcomes in infants with critical congenital heart disease (CCHD). Method Neonatal brain magnetic resonance imaging..

Read More
thumbnail
0 comment

The role of three-dimensional printed cardiac models in the management of complex congenital heart diseases

Abstract Background Three-dimensional printing is a process enabling computer-assisted conversion of imaging data from patients into physical “printed” replicas. This has been extrapolated to reconstructing patient-specific cardiac models in . The..

Read More