Archives

thumbnail
0 comment

Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries

Abstract Background The global prevalence of congenital heart disease (CHD) is increasing. Research on patient-reported outcomes (PROs) predominantly originates from high-income countries, resulting in an incomplete understanding of the true global..

Read More
thumbnail
0 comment

The Relationship Between the Type of Microorganisms Isolated in Cultures and Outcomes in Children on Extracorporeal Membrane Oxygenation Support Following…

Abstract Objetives Extracorporeal membrane oxygenation (ECMO) after surgery for congenital heart disease (CHD) provides hemodynamic support to patients when their myocardial function is temporarily affected. Postoperative infections in children with..

Read More
thumbnail
0 comment

Circulating amino acid levels in infants undergoing congenital heart disease surgery: near global decrease following cardiopulmonary bypass and impact of…

Abstract Introduction Amino acids (AAs) serve diverse roles, and insufficient delivery is associated with worse outcomes in ill patients. In the case of congenital heart disease (CHD) surgery with cardiopulmonary..

Read More
thumbnail
0 comment

Tailored preoperative assessment in neonatal cardiac surgery: a European Congenital Heart Surgeons Association study

Abstract OBJECTIVES Current preoperative counselling in neonatal cardiac surgery is mainly focused on the primary procedure. However, other factors must be considered when evaluating the surgical risk of a neonate...

Read More
thumbnail
0 comment

Cardiac surgery-associated acute kidney injury in neonatal Norwood procedure: incidence, risk factors and impact on mortality and outcomes

Abstract OBJECTIVES Acute kidney injury commonly complicates congenital heart surgery with cardiopulmonary bypass, increasing morbidity and mortality. This study aimed to evaluate risk factors for postoperative acute kidney injury and..

Read More
thumbnail
0 comment

Long-Term Survival and Patient-Reported Outcomes After Staged Reconstructive Surgery for Hypoplastic Left Heart Syndrome

Abstract Background Survival for hypoplastic left heart syndrome (HLHS) and variants has improved over the past 4 decades; however, survival remains low compared with other forms of congenital heart disease...

Read More
thumbnail
0 comment

Adaptation mechanisms of cardiomyocytes isolated from patients with Tetralogy of Fallot to hypoxic conditions

Abstract Introduction Congenital cardiac defects disrupt circulation and oxygenation due to structural changes in the heart. Tetralogy of Fallot is the most common cyanotic congenital heart disease, accounting for 5..

Read More
thumbnail
0 comment

A rule-based clinical decision support system for detection of acute kidney injury after pediatric cardiac surgery

Abstract Background Acute kidney injury (AKI) is common in children with congenital heart disease following open-heart surgery with cardiopulmonary bypass (CPB). Early AKI detection in critically ill children requires clinician..

Read More
thumbnail
0 comment

Patient Characteristics and Extracorporeal Membrane Oxygenation Outcomes at Nelson Mandela Children’s Hospital: A South African Experience

Abstract This study aimed to describe patient characteristics, mortality, and morbidity outcomes in children at a South African extracorporeal membrane oxygenation (ECMO) center. Fifty-seven patients required ECMO from 2018 to..

Read More
thumbnail
0 comment

Evaluation of Integrated Arterial Filter Oxygenator vs. External Arterial Filters on Clinical Outcomes and Neurocognitive Function in Pediatric Cardiac Surgery:…

Abstract Background and Aims Innovative advancements in cardiopulmonary bypass (CPB) configurations, such as surface coating, blood filtration, and miniaturization, aim to reduce gaseous microemboli (GME) that contribute to embolic organ..

Read More
thumbnail
0 comment

Routine Use of an On-Table Extubation Protocol in Pediatric Cardiac Surgery—Our Experience With Life in the Fast Lane

Abstract Background We undertook this study to evaluate the efficacy of an on-table extubation protocol and to assess the magnitude of benefits when implemented as a routine practice in a..

Read More
thumbnail
0 comment

Outcomes after hospital discharge in children requiring post-cardiotomy extracorporeal membrane oxygenation: A binational retrospective cohort study

Abstract Objectives To describe longer-term survival and morbidity outcomes after hospital discharge in a binational cohort of children who required extracorporeal membrane oxygenation after cardiac surgery. Methods This was a..

Read More
thumbnail
0 comment

Effect of Dexmedetomidine on Cerebrovascular Carbon Dioxide Reactivity During Pediatric Cardiac Surgery With Cardiopulmonary Bypass

Abstract Objective To assess the effects of dexmedetomidine (DEX) on cerebrovascular autoregulation in children with congenital heart disease (CHD) using transcranial color-coded duplex sonography (TCCD). Design Randomized controlled trial. Setting..

Read More
thumbnail
0 comment

Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review

Abstract Background The human bioaccumulation of micro- and nano-plastics (MNPs) is increasingly being recognised in the aetiology and pathophysiology of human disease. Objective This systematic scoping review aims to provide..

Read More
thumbnail
0 comment

Intraoperative Assessment of Cerebral Autoregulation With Cerebral Oximetry Index in Neonates Undergoing Cardiac Surgery: A Pilot Study

Abstract Abstract Objective To investigate cerebral autoregulation impairment during neonatal cardiac surgery. Design A retrospective observational study. Setting Single-center, university teaching children’s hospital. Participants Neonates undergoing surgery for critical congenital..

Read More
thumbnail
0 comment

A Year of Advances in Cardiac Surgery, Transplantation, and Anesthetic Management

Introduction Superlatives and acronyms abound in this year’s edition of annual noteworthy literature for Seminars in Cardiothoracic and Vascular Anesthesia. By the numbers, over 22 000 publications from 2024 were screened, and approximately..

Read More
thumbnail
0 comment

A Machine Learning-Based Clustering Analysis to Explore Bisphenol A and Phthalate Exposure from Medical Devices in Infants with Congenital Heart…

Abstract Background: Plastic-containing medical devices are commonly used in critical care units and other patient care settings. Patients are often exposed to xenobiotic agents that are leached out from plastic-containing..

Read More
thumbnail
0 comment

Near-infrared spectroscopy to monitor cerebral and renal oxygen saturation during cardiopulmonary bypass surgery for paediatric congenital heart disease: study protocol…

Abstract Background Current indicators for monitoring intraoperative organ function remain predominantly indirect, delayed and non-specific, particularly in paediatric populations undergoing congenital heart surgery, where multifactorial influences further complicate functional assessments. Emerging..

Read More
thumbnail
0 comment

Humoral and Cellular Immune Response to SARS-CoV-2 in Children Undergoing Cardiac Surgery

Abstract Evaluating the impact of cardiac surgery on humoral and cellular immunity in pediatric congenital heart disease patients with prior Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection or vaccination..

Read More
thumbnail
0 comment

Perioperative Normoxia versus Hyperoxia in Neonates with Cyanotic Heart Disease Undergoing Cardiac Surgery: A Randomized Controlled Trial

Abstract BACKGROUND Exposure to supra-physiologic levels of oxygen has been associated with end-organ damage and worse outcomes across multiple populations related to oxidative stress and inflammation. There is limited evidence..

Read More
thumbnail
0 comment

Extracorporeal Membrane Oxygenation in Pediatric Patients With Congenital Heart Disease: Surgical Considerations

Abstract The use of extracorporeal membrane oxygenation (ECMO) in the paediatric population has increased over time, with the ability to rescue pulmonary and cardiovascular deterioration. ECMO can be utilised by..

Read More
thumbnail
0 comment

Over 3,000 Minimally Invasive Thoracotomies From the European Congenital Heart Surgeons Association for Quality Repairs of the Most Common Congenital…

Abstract Background Minimally invasive thoracotomies to repair selected congenital heart defects are considered only a cosmetic alternative approach by many; however, they represent the routine alternative in centers of expertise...

Read More
thumbnail
0 comment

Is altitude friend or foe in unrepaired congenital heart disease? A case report

Abstract Background Some unrestrictive congenital shunts put patients at high risk for developing irreversible pulmonary vascular disease if not closed in the first year of life. Living at high altitude..

Read More
thumbnail
0 comment

Minimally invasive cardiac surgery in congenital heart diseases: the new horizon

Abstract Introduction Sternotomy has been the most common approach for the correction of congenital cardiac defects, and questions arise surrounding the safety, feasibility, and cost-effectiveness of implementing minimally invasive techniques..

Read More
thumbnail
0 comment

Red blood cell transfusion management for people undergoing cardiac surgery for congenital heart disease

Abstract Background Congenital heart disease is the most common neonatal congenital condition. Surgery is often necessary. Patients with congenital heart disease are potentially exposed to red cell transfusion preoperatively, intraoperatively..

Read More
thumbnail
0 comment

Outcomes of Neonatal Cardiac Surgery: A European Congenital Heart Surgeons Association Study

Abstract Background We evaluated outcomes of neonatal cardiac surgery at hospitals affiliated with the European Congenital Heart Surgeons Association (ECHSA). Methods All patients ≤30 days of life undergoing a cardiac..

Read More
thumbnail
0 comment

Cerebral Hemodynamic Monitoring via Transcranial Doppler Ultrasound and Near-Infrared Spectroscopy for Risk-Stratified Pediatric Cardiac Surgery Patients

Abstract Background The objective of this study was to evaluate mean cerebral blood flow velocity, gaseous microemboli (GME) counts, regional cerebral oxygen saturation (rSO2), and clinical outcomes using multimodality neuromonitoring..

Read More
thumbnail
0 comment

Circular Shunt: A Loop Not to Be Ignored

Abstract A circular shunt, initially described by Shone et al. in 1962, refers to abnormal blood recirculation through complete intracardiac or intra- and extracardiac communications, bypassing the capillary beds. This..

Read More
thumbnail
0 comment

Prothrombotic Microvesicle Generation in Pediatric Cardiopulmonary Bypass: A Pilot Observational Study

Abstract Over 10% of children develop thrombosis after cardiac surgery for congenital heart disease. Children with a single ventricle physiology have the highest risk of thrombosis associated with increased length..

Read More
thumbnail
0 comment

Prevalence, Risk Factors, and Outcomes of Hospital-Acquired Infections in Children After Congenital Heart Surgery

Abstract Background Hospital-acquired infections (HAIs) are associated with morbidity and mortality in children following congenital cardiac surgery. Our center performs approximately 200 congenital surgeries a year, but infection rates and..

Read More