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Modulating the Inflammatory Response With Hemadsorption (CytoSorb) in Patients Undergoing Major Aortic Surgery

This retrospective pilot study was undertaken to evaluate the effect of hemadsorption (HA) with CytoSorb (CytoSorbents Corporation, Monmouth Junction, NJ) on changes in inflammatory markers in patients undergoing aortic surgery...

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Incidental Detection of Factor XII Deficiency Following Coronary Artery Bypass Grafting

Abstract Coagulation Factor XII (fXII), the Hageman factor, is a procoagulant 80kDa glycoprotein with a plasma concentration of about 40 µg/mL (approximately 500 nmol/L). Plasma fXII is mainly synthesized in..

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Pitfalls of Commonly Used Anticoagulation Monitoring Techniques in Antiphospholipid Syndrome During Cardiopulmonary Bypass

Abstract Antiphospholipid Syndrome (APS) is an immunologic disorder that causes a state of hypercoagulability that can result in recurrent venous and arterial thromboses. Patients who experience APS may develop cardiac..

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Activated Clotting Time (ACT) for Monitoring of Low-Dose Heparin: Performance Characteristics in Healthy Adults and Critically Ill Patients

Abstract Dose adjustment of unfractionated heparin (UFH) anticoagulation is an important factor to reduce hemorrhagic events. High doses of heparin can be monitored by Activated Clotting Time (ACT). Because of..

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Prothrombin Complex Concentrate vs. Fresh Frozen Plasma in Adult Patients Undergoing Heart Surgery – A Pilot Randomised Controlled Trial (PROPHESY…

Summary There is equipoise regarding the use of prothrombin complex concentrate vs. fresh frozen plasma in bleeding patients undergoing cardiac surgery. We performed a pilot randomised controlled trial to determine..

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