Abstract Introduction Blood transfusion is associated with adverse events and should be prevented. Preoperative identification of patients at risk is necessary and makes subsequent preventive intervention possible. Many risk models..
Read MoreAbstract Objective: To create and verify a model that predicts the risk of stress hyperglycemia (SHG) in patients without diabetes after cardiac surgery. Design: Retrospective analysis. Methods: This retrospective analysis analyzed patients without..
Read MoreAbstract Background Cardiac surgery on cardiopulmonary bypass (CPB) may alter platelet (PLT) function causing bleeding. The goal of this study is to evaluate the hemostatic effect of PRT-PLTs compared to..
Read MoreAbstract Background Evidence for the effectiveness of the Sonoclot analyzer in improving clinical outcomes in disseminated intravascular coagulation (DIC) is lacking. Objective To evaluate the effectiveness of an algorithm based..
Read MoreAbstract Background Cancer surgery patients are among those most at high risk of perioperative anemia. Allogeneic transfusions are linked to adverse effects, including increased cancer recurrence and mortality. Intraoperative cell..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) supports severe cardiorespiratory failure but carries a significant bleeding risk. This systematic review aims to report bleeding definitions in studies involving neonates and children treated..
Read MoreAbstract Background: Transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO) are leading causes of transfusion-related morbidity and mortality. Soluble factors in red blood cell (RBC) supernatant may increase..
Read MoreAbstract Background: The objective of this study was to describe thrombin generation in children undergoing cardiac surgery with cardiopulmonary bypass (CPB). Change in the endogenous thrombin potential (ETP) across three..
Read MoreAbstract Evaluating the impact of cardiac surgery on humoral and cellular immunity in pediatric congenital heart disease patients with prior Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection or vaccination..
Read MoreAbstract Objectives Intraoperative cell salvage (ICS) is broadly used in high-risk surgical procedures to facilitate rapid autologous red blood cell transfusion, minimizing the need for allogeneic blood and its associated..
Read MoreAbstract Background: Postoperative Acute kidney injury (AKI) is a significant concern for cardiac surgery patients with chronic kidney disease (CKD). Effective pharmacological interventions to mitigate these risks are urgently needed...
Read MoreAbstract Objective Hemoconcentration and cell saver use are blood conservation techniques that are often used in cardiac surgery to salvage the patient's own blood to reduce autologous transfusion. The purpose..
Read MoreAbstract Perioperative pulmonary arterial hypertension (PAH) is a common complication of chest surgery with cardiopulmonary bypass (CPB) and its etiology is multifactorial. Patients undergoing this surgery often have underlying conditions,..
Read MoreAbstract Objectives To study the association between bleeding and acute kidney injury (AKI). Design Post-hoc study of a randomized trial of 4% albumin versus Ringer's acetate for cardiopulmonary bypass priming..
Read MoreAbstract OBJECTIVES The question whether minimally invasive extracorporeal circulation (MiECC) represents the optimal perfusion strategy in cardiac surgery remains unanswered. We sought to systematically review the entire literature and thoroughly..
Read MoreAbstract Background There remains significant variability in the use of intraoperative mechanical circulatory support in lung transplantation. This report details our outcomes using elective cardiopulmonary bypass (CPB) in lung transplantation...
Read MoreAbstract Background Congenital heart disease is the most common neonatal congenital condition. Surgery is often necessary. Patients with congenital heart disease are potentially exposed to red cell transfusion preoperatively, intraoperatively..
Read MoreAbstract Importance Excessive bleeding is a common and prognostically important complication of cardiac surgery. For bleeding related to coagulation factor deficiency, frozen plasma is the most used therapy. Preliminary trials indicate..
Read MoreAbstract Objective(s) This study was designed to assess the relative association between adjunctive fresh frozen plasma (FFP) or adjunctive cryoprecipitate and morbidity and mortality in cardiac surgery patients receiving platelets..
Read MoreAbstract Objectives Severe perioperative bleeding occurs in over 30 % of patients on ticagrelor undergoing isolated coronary artery bypass grafting (i-CABG) before completing the recommended 3-day washout. Intraoperative ticagrelor removal with..
Read MoreAbstract Objectives: Previous studies have demonstrated an association between transfusion and increased organ dysfunction. We sought to determine the association between transfusion of blood components (red blood cell [RBC], plasma, platelet,..
Read MoreAbstract BACKGROUND: Postoperative anemia is a common complication after cardiac surgery, often persisting for months and substantially affecting patient recovery. Despite its prevalence, optimal treatment strategies are lacking. We aimed..
Read MoreAbstract Following cardiopulmonary bypass (CPB) surgery, patients may experience vasoplegic or vasogenic shock syndrome. This condition has a variable incidence, reaching up to 44% in high-risk patients, with mortality rates..
Read MoreAbstract Background The optimal fluid management strategy for patients undergoing on-pump cardiac surgery was controversial regarding the fluid types. This study aimed to compare the impact of hydroxyethyl starch (HES)..
Read MoreAbstract Introduction Cardiac surgery is fraught with increased consumption of blood and blood products. Various strategies for blood conservation have been described. Our aim was to study the impact of..
Read MoreAbstract Background Hemolysis, variably defined in mechanical circulatory support (MCS), is understudied in percutaneous left ventricular assist devices. We characterize hemolytic sequelae of Impella 5.5-supported patients in the largest series..
Read MoreAbstract Background Previously, two international surveys have addressed the wider application of platelet collection by apheresis technology and practical issues of platelet transfusion. Study design and methods A questionnaire was..
Read MoreAbstract Introduction Major perioperative blood loss often necessitates allogeneic blood transfusions, leading to adverse outcomes and straining healthcare resources. Intraoperative cell salvage (ICS) offers benefits like reduced adverse reactions, optimised blood..
Read MoreAbstract Objective: Axillary artery cannulation techniques continue to improve and find application throughout cardiac surgery. Yet, early outcomes are poorly documented versus femoral or central arterial cannulation in right minithoracotomy..
Read MoreAbstract BACKGROUND: This study’s purpose was to assess whether larger volumes of reinfused unwashed shed autologous blood (SAB) were associated with adverse events within 30 days for patients undergoing open..
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