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Quantification of Operational Learning in Minimal Invasive Extracorporeal Circulation

Abstract Minimal invasive extracorporeal circulation (MiECC) has initiated important new efforts within science and technology towards a more physiologic perfusion. In this study, we aim to investigate the learning curve..

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Relationship between maximum clot firmness in ROTEM® and postoperative bleeding after coronary artery bypass graft surgery in patients using clopidogrel

Abstract Background:  The aim of the present study was to investigate the relationship between maximum clot firmness (MCF) in rotational thromboelastometry (ROTEM®) and postoperative bleeding in patients on clopidogrel after..

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Facilitating technologies in minimally invasive aortic valve replacement: a propensity score analysis

Abstract OBJECTIVES Minimally invasive aortic valve replacement (MIAVR) can be technically demanding and may lead to prolonged operative time. We evaluated the intraoperative and postoperative patient outcomes following implementation of..

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Comparison of Two Major Perioperative Bleeding Scores for Cardiac Surgery Trials: Universal Definition of Perioperative Bleeding in Cardiac Surgery and…

Abstract Editor’s Perspective What We Already Know about This Topic Major bleeding can occur during cardiac surgery. Although different scoring systems exist, the assessment of bleeding can be variable, and..

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Comprehensive blood conservation program in a new congenital cardiac surgical program allows bloodless surgery for the Jehovah Witness and a…

Abstract Background: Cardiac surgery on Jehovah's Witnesses (JW) can be challenging, given the desire to avoid blood products. Establishment of a blood conservation program involving the pre-, intra- and post-operative..

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The effect of protamine dosing variation on bleeding and transfusion after heparinisation for cardiopulmonary bypass

Abstract Introduction: Accurate dosing of protamine reversal following on-pump cardiac surgical procedures is challenging, with both excessive and inadequate administration recognised to increase bleeding risk. We aimed to examine the..

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The use of acute normovolemic hemodilution in paediatric cardiac surgery

Abstract Background Acute normovolemic hemodilution (ANH) is considered safe and effective in decreasing perioperative transfusion in paediatric populations undergoing high blood‐loss surgeries. We determined the association between ANH and the..

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Safety of Perioperative Aprotinin Administration During Isolated Coronary Artery Bypass Graft Surgery: Insights From the ART (Arterial Revascularization Trial)

Abstract Background There is still uncertainty about the safety of aprotinin for coronary artery bypass graft surgery. The ART (Arterial Revascularization Trial) was designed to compare survival after bilateral versus..

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The association between borderline pre‐operative anaemia in women and outcomes after cardiac surgery: a cohort study

Summary Anaemia is common before cardiac surgery and is associated with increased morbidity and mortality. The World Health Organization (WHO) definition of anaemia is lower for women than for men..

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Transfusion and blood stream infections after coronary surgery

Abstract The aim of this study was to evaluate the impact of blood transfusion on bloodstream infections. This study included 2764 patients who underwent isolated coronary artery bypass grafting. Blood..

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Open Cardiac Surgery without Blood and Blood Products Transplantation

ABSTRACT Background: Blood transfusions are the most common type of tissue and organ transplantation. Perioperative and postoperative transfusions may cause morbidity and mortality and transfusion should based on only hematocrit values..

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Cardiopulmonary Bypass-Induced Coagulopathy in Paediatric Patients: The Role of Platelets in Postoperative Bleeding. A Preliminary Study

Abstract Introduction Paediatric patients are particularly prone to cardiopulmonary bypass (CPB)‐induced coagulopathy mainly due to haemodilution, consumption of coagulation factors and hypothermia. The aim of the present study was to..

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International consensus statement on the peri‐operative management of direct oral anticoagulants in cardiac surgery

Summary Despite current recommendations on the management of severe peri‐operative bleeding, there is no pragmatic guidance for the peri‐operative monitoring and management of cardiac surgical patients taking direct oral anticoagulants...

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Prediction of Bleeding in Pediatric Cardiac Surgery Using Clinical Characteristics and Prospective Coagulation Test Results

Abstract Bleeding caused by coagulopathy is common in children undergoing cardiac surgery and causes adverse outcomes. Coagulation testing assists selection of treatments to stop bleeding but has an uncertain role..

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A Comparison of Prothrombin Complex Concentrate and Recombinant Activated Factor VII for the Management of Bleeding With Cardiac Surgery

Abstract Bleeding following cardiac surgery that warrants transfusion of blood products is associated with significant complications, including increased mortality at 1 year following surgery. Factor concentrates, such as prothrombin complex..

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Anemia in Cardiac Surgery – Can Something Bad Get Worse?

Abstract Introduction Anemia and blood transfusion are risk factors for morbidity/mortality in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The objective of this study is to analyze the association..

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Determining Optimal Treatment to Correct Preoperative Anemia and Reduce Perioperative Allogeneic Blood Transfusions in Cardiac Surgery: A Retrospective Cohort Study

Abstract Objective Preoperative anemia management reduces red blood cell (RBC) transfusion and adverse outcomes, but how best to optimize the patient’s hemoglobin (Hgb) before cardiac surgery remains unclear. The authors..

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Exposure–Response Relationship of Tranexamic Acid in Cardiac Surgery: A Model-based Meta-analysis

Background It is unclear whether high-dose regimens of tranexamic acid in cardiac surgery (total dose, 80 to 100 mg/kg) confer a clinical advantage over low-dose regimens (total dose, approximately 20..

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Central Versus Peripheral Arterial Cannulation for Veno-Arterial Extracorporeal Membrane Oxygenation in Post-Cardiotomy Patients

Abstract Different arterial cannulation strategies are feasible for veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in postcardiotomy shock. We aimed to analyze potential benefits and safety of different arterial cannulation strategies. We..

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Managing Massive Transfusion Protocol During Cardiopulmonary Bypass in the Setting of Penetrating Traumatic Injury

Abstract A 34-year-old African American man was brought to the trauma resuscitation area with 2 gunshot wounds to his right anterior chest below his clavicle and his left back. On..

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Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury

Abstract Objective Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) serves to hemoconcentrate blood volume to avoid allogeneic blood transfusions. Previous studies have determined CUF volumes as a continuous variable are..

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Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time

Abstract Objective To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those..

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