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Rationale and design of the intravenous iron for treatment of anemia before cardiac surgery trial

Abstract Background Approximately 20% to 30% of patients awaiting cardiac surgery are anemic. Anemia increases the likelihood of requiring a red cell transfusion and is associated with increased complications, intensive care,..

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Optimising bloodless cardiovascular surgery for Jehovah’s Witnesses and beyond

Abstract Emerging evidence suggests surgical outcomes of patients undergoing cardiovascular surgery that refuse autologous transfusion is comparable to those who accept whole blood product transfusions. There are several methods that..

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Intraoperative cell salvage for obstetrics: a prospective randomized controlled clinical trial

Abstract Background The latest basic studies and clinical evidence have confirmed the safety and efficacy of intraoperative autologous blood cell transfusion in cardiac surgery and orthopaedics. However, in caesarean section,..

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Comparison of Anticoagulation Strategies in Patients Requiring Venovenous Extracorporeal Membrane Oxygenation: Heparin Versus Bivalirudin

Abstract OBJECTIVES:  Extracorporeal membrane oxygenation is a life-sustaining therapy for severe respiratory failure. Extracorporeal membrane oxygenation circuits require systemic anticoagulation that creates a delicate balance between circuit-related thrombosis and bleeding-related..

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Pro: Priming the Cardiopulmonary Bypass Circuit With Fresh Frozen Plasma Reduces Bleeding in Complex Cardiac Surgery

Abstract CARDIAC SURGERY is inherently complex and is associated with a high risk of perioperative bleeding. As such, it is responsible for a disproportionate percentage of annual blood product usage..

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Association of Plasma Fibrinogen and Thromboelastography With Blood Loss in Complex Cardiac Surgery

Abstract Postoperative coagulopathic bleeding is common in cardiac surgery and is associated with increased morbidity and mortality. Ideally, real-time information on in-vivo coagulation should be available. However, up to now..

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Randomized Pilot Trial of Acute Normovolemic Hemodilution in Pediatric Cardiac Surgery Patients

Abstract Background: Due to the substantial improvement in survival among pediatric patients undergoing congenital heart surgery, reducing early and long-term morbidity is becoming the major focus of care. Blood transfusion is..

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Systemic Hypertension in Pediatric Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Systemic hypertension (HTN) is a recognized complication of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in children. We sought to determine the prevalence and associated features of HTN in a..

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Influence of cardiopulmonary bypass set-up and management on clinical outcomes after minimally invasive aortic valve surgery

Abstract Introduction: Minimally invasive aortic valve replacement (MIAVR) requires changes in cannulation strategy and cardiopulmonary bypass (CPB) management when compared to the conventional approach (CAVR). We aimed at evaluating if..

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Platelets and extra-corporeal membrane oxygenation in adult patients: a systematic review and meta-analysis

Abstract Despite increasing improvement in extracorporeal membrane oxygenation (ECMO) technology and knowledge, thrombocytopenia and impaired platelet function are usual findings in ECMO patients and the underlying mechanisms are only partially..

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A survey of patient blood management for patients undergoing cardiac surgery in nine European countries

Abstract Study objective To describe and compare patient blood management (PBM) practices in cardiac surgery in nine European countries and identify the main risk factors for bleeding or transfusion according..

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Albumin in adult cardiac surgery: a narrative review

Abstract Purpose Intravascular fluids are a necessary and universal component of cardiac surgical patient care. Both crystalloids and colloids are used to maintain or restore circulating plasma volume and ensure..

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Factors associated with delirium after cardiac surgery: A prospective cohort study

Abstract Background: Delirium is a frequent complication after cardiac surgery and is associated with a higher incidence of morbidity and mortality and a prolonged hospital stay. However, knowledge of the variables..

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Novel cardiac protocols among adults intervened in the caribbean

Abstract Background Myocardial protection is crucial for successful revascularization; multiple doses mixtures have been the cornerstone in adults. Del Nido cardioplegia (DLN CP) is used in pediatric population and in..

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Endoscopic Tricuspid Valve Surgery is a Safe and Effective Option

Abstract Objective Isolated tricuspid surgery through median sternotomy can be associated with a high morbidity and mortality. Reports of minimally invasive isolated tricuspid valve operations are rare, but the outcomes..

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Oxygen delivery-guided perfusion for the prevention of acute kidney injury: A randomized controlled trial

Abstract Objectives The reduction of postoperative acute kidney injury in patients undergoing cardiopulmonary bypass surgery using an oxygen delivery-guided perfusion strategy (oxygen delivery strategy) for cardiopulmonary bypass management compared with..

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The Use of Extracorporeal Circulation in Suspected Brain Dead Organ Donors with Cardiopulmonary Collapse

Abstract Bleeding and thrombosis-related complications are common in pediatric cardiac patients supported by extracorporeal membrane oxygenation (ECMO) and are associated with morbidity and mortality. The purpose of this study was..

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Traditional and emerging technologies for washing and volume reducing blood products

Abstract Millions of blood components including red blood cells, platelets, and granulocytes are transfused each year in the United States. The transfusion of these blood products may be associated with..

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Intraoperative Cell Saving: Is the Solution the Actual Problem?

Abstract Allogenic blood is a scarce, precious, and expensive resource that is not always available on demand. After termination of cardiopulmonary bypass, a large amount of residual pump blood remains..

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Myocardial Protection in Adult Cardiac Surgery With del Nido Versus Blood Cardioplegia: A Systematic Review and Meta-Analysis

Abstract Background  in adult cardiac surgery is commonly achieved with either multidose blood  or single-dose del Nido crystalloid cardioplegia. Aim The aim of this systematic review and meta-analysis was to compare..

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Preoperative Intra-Aortic Balloon Pumps in Cardiac Surgery: A Propensity Score Analysis

Abstract Introduction The role of intra-aortic balloon pumps (IABP) in high-risk patients undergoing  (CABG) surgery remains controversial. We report the 5-year experience from a new Australian centre. Methods We retrospectively analysed..

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Comparison of 4-Factor Prothrombin Complex Concentrate With Frozen Plasma for Management of Hemorrhage During and After Cardiac Surgery

Abstract Importance  Approximately 15% of patients undergoing cardiac surgery receive frozen plasma (FP) for bleeding. Four-factor prothrombin complex concentrates (PCCs) have logistical and safety advantages over FP and may be a..

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Minimally Invasive Versus Sternotomy for Mitral Surgery in the Elderly: A Systematic Review and Meta-Analysis

Abstract Objective The safety of minimally invasive mitral valve surgery (MIMVS) in elderly patients is still debated. Our objective was to perform a systematic review and meta-analysis of studies comparing..

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Efficacy and cost-effectiveness of cell saver usage in the repair of thoracic aortic aneurysms and dissections

Abstract Introduction: A substantial amount of blood loss occurs during the open repair of aortic aneurysms or dissections. The aim of the present study is to determine the efficacy and..

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Perioperative Cryoprecipitate Waste Reduction

Abstract Improvement of operating room efficiency regarding perioperative blood product transfusion is fundamental for surgical patients. The aim of this study was to 1) assess the use of cryoprecipitate in..

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Extracellular Vesicles in Autologous Cell Salvaged Blood in Orthopedic Surgery

  Abstract Background: Cell salvage is highly recommended in orthopedic surgery to avoid allogeneic transfusions. Preparational steps during cell salvage may induce extracellular vesicle (EV) formation with potential thrombogenic activity...

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The risk factors for delayed recovery in patients with cardiopulmonary bypass

Abstract Cardiopulmonary bypass (CPB) is very commonly performed among the cardiovascular surgeries, and delayed recovery (DR) is a kind of serious complications in patients with CPB. It is necessary to..

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The failure of retrograde autologous priming of the cardiopulmonary bypass circuit to reduce blood use after cardiac surgical procedures.

Abstract UNLABELLED:Hemodilution during cardiopulmonary bypass (CPB) is a primary risk factor for blood transfusion in cardiac surgical patients. Priming of the CPB circuit with the patients' own blood (retrograde autologous..

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Hematic Antegrade Repriming: A Reproducible Method to Decrease the Cardiopulmonary Bypass Insult.

Abstract The current practice of cardiopulmonary bypass (CPB) requires a preoperative priming of the circuit that is frequently performed with crystalloid solutions. Crystalloid priming avoids massive embolism but is unable..

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Minimally Invasive Extracorporeal Technologies Perspective in Pediatric Cardiac Surgery

Abstract Minimally invasive extracorporeal technologies (MiECT) are in great expansion in the literature and have an impact in adult cardiac surgery, however, a future challenge will be to expand MiECT..

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