Abstract Background Variability in transfusion outcomes and excessive postoperative bleeding represents a significant problem in cardiac surgery. The effort to reduce bleeding complications and transfusion outcomes is desirable. Our study..
Read MoreAbstract Objective To explore whether pre-cannulation international normalized ratio (INR) is associated with in-hospital mortality in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) patients. Design Retrospective observational cohort study. Setting Quaternary care..
Read MoreAbstract Objective Currently, several near-infrared spectroscopy oximetry devices are used for detecting cerebral ischemia during cardiopulmonary bypass (CPB) surgery. We investigated whether two different models of near-infrared spectroscopy oximetry devices..
Read MoreAbstract Introduction Multiple studies have shown a decrease in the inflammatory response with minimized bypass circuits leading to less complications and mortality rate. On the other hand, some other studies..
Read MoreAbstract Background The dose of protamine required following cardiopulmonary bypass (CPB) is often determined by the dose of heparin required pre-CPB, expressed as a fixed ratio. Dosing based on mathematical..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has been used with increasing frequency to support patients with acute respiratory failure, most commonly, and severe forms of acute respiratory distress syndrome (ARDS). The..
Read MoreAbstract Purpose of review The collection of shed blood and its reinfusion has been termed ‘cell salvage’ or ‘autotransfusion’. This review will summarize the historical foundation of cell salvage and summarize recent..
Read MoreAbstract Purpose: This studywas designed to optimize the latestgeneration venovenous (vv)-extra-corporeal membrane oxygenation(ECMO)-circuit configuration andsettings based on the evaluation ofblood oxygenation and CO 2 removaldeterminants in patients with severeacute respiratory..
Read MoreBlood transfusion is a critical and life-saving facet of the care for cardiothoracic surgery patients. Inherent to the transfusing of blood is the understanding of the preservation of blood as..
Read MoreAbstract Patients with inherited anemia and hemoglobinopathies (such as sickle cell disease and β-thalassemia) are treated with red blood cell (RBC) transfusions to alleviate their symptoms. Some of these patients..
Read MoreAbstract Acute respiratory distress syndrome (ARDS) after cardiac surgery is reported with a widely variable incidence (from 0.4%-8.1%). Cardiac surgery patients usually are affected by several comorbidities, and the development..
Read MoreAbstract Patient blood management (PBM) has been proposed as a standard of care in modern . PBM-related interventions usually are implemented as bundles, but randomized controlled trials on the implementation of..
Read MoreAbstract Background Approximately 20% to 30% of patients awaiting cardiac surgery are anemic. Anemia increases the likelihood of requiring a red cell transfusion and is associated with increased complications, intensive care,..
Read MoreAbstract Emerging evidence suggests surgical outcomes of patients undergoing cardiovascular surgery that refuse autologous transfusion is comparable to those who accept whole blood product transfusions. There are several methods that..
Read MoreAbstract Background The latest basic studies and clinical evidence have confirmed the safety and efficacy of intraoperative autologous blood cell transfusion in cardiac surgery and orthopaedics. However, in caesarean section,..
Read MoreAbstract OBJECTIVES: Extracorporeal membrane oxygenation is a life-sustaining therapy for severe respiratory failure. Extracorporeal membrane oxygenation circuits require systemic anticoagulation that creates a delicate balance between circuit-related thrombosis and bleeding-related..
Read MoreAbstract CARDIAC SURGERY is inherently complex and is associated with a high risk of perioperative bleeding. As such, it is responsible for a disproportionate percentage of annual blood product usage..
Read MoreAbstract Postoperative coagulopathic bleeding is common in cardiac surgery and is associated with increased morbidity and mortality. Ideally, real-time information on in-vivo coagulation should be available. However, up to now..
Read MoreAbstract Background: Due to the substantial improvement in survival among pediatric patients undergoing congenital heart surgery, reducing early and long-term morbidity is becoming the major focus of care. Blood transfusion is..
Read MoreAbstract Systemic hypertension (HTN) is a recognized complication of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in children. We sought to determine the prevalence and associated features of HTN in a..
Read MoreAbstract Introduction: Minimally invasive aortic valve replacement (MIAVR) requires changes in cannulation strategy and cardiopulmonary bypass (CPB) management when compared to the conventional approach (CAVR). We aimed at evaluating if..
Read MoreAbstract Despite increasing improvement in extracorporeal membrane oxygenation (ECMO) technology and knowledge, thrombocytopenia and impaired platelet function are usual findings in ECMO patients and the underlying mechanisms are only partially..
Read MoreAbstract Study objective To describe and compare patient blood management (PBM) practices in cardiac surgery in nine European countries and identify the main risk factors for bleeding or transfusion according..
Read MoreAbstract Purpose Intravascular fluids are a necessary and universal component of cardiac surgical patient care. Both crystalloids and colloids are used to maintain or restore circulating plasma volume and ensure..
Read MoreAbstract Background: Delirium is a frequent complication after cardiac surgery and is associated with a higher incidence of morbidity and mortality and a prolonged hospital stay. However, knowledge of the variables..
Read MoreAbstract Background Myocardial protection is crucial for successful revascularization; multiple doses mixtures have been the cornerstone in adults. Del Nido cardioplegia (DLN CP) is used in pediatric population and in..
Read MoreAbstract Objective Isolated tricuspid surgery through median sternotomy can be associated with a high morbidity and mortality. Reports of minimally invasive isolated tricuspid valve operations are rare, but the outcomes..
Read MoreAbstract Objectives The reduction of postoperative acute kidney injury in patients undergoing cardiopulmonary bypass surgery using an oxygen delivery-guided perfusion strategy (oxygen delivery strategy) for cardiopulmonary bypass management compared with..
Read MoreAbstract Bleeding and thrombosis-related complications are common in pediatric cardiac patients supported by extracorporeal membrane oxygenation (ECMO) and are associated with morbidity and mortality. The purpose of this study was..
Read MoreAbstract Millions of blood components including red blood cells, platelets, and granulocytes are transfused each year in the United States. The transfusion of these blood products may be associated with..
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