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Risk factors for allogeneic red blood cell transfusion in adult spinal deformity surgery

Abstract Study Design Retrospective study. Purpose To investigate the risk factors for allogeneic red blood cell (RBC) transfusion in adult spinal deformity (ASD) surgery. Overview of Literature Studies have not..

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The Role of Veno-Arterial Extracorporeal Membrane Oxygenation in Amniotic Fluid Embolism: A Case Report

Abstract Introduction: Amniotic fluid embolism (AFE) is a catastrophic complication of pregnancy with high mortality rate. It is an inflammatory response leading to cardiovascular collapse. We present a case of successful..

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Factors associated with acute kidney injury after on-pump coronary artery bypass grafting

Abstract Background Acute kidney injury (AKI) frequently occurs as a complication of cardiac surgery and cardiopulmonary bypass (CPB). Its prevalence and severity are determined by various preoperative and intraoperative factors...

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Comprehensive perioperative blood management in patients undergoing elective bypass cardiac surgery: Benefit effect of health care education and systematic correction…

Abstract Study objective The aim of this study was to investigate the efficacy of a two-step patient blood management (PBM) program in red blood cell (RBC) transfusion requirements among patients..

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Evaluation of Point-of-Care-Directed Coagulation Management in Pediatric Cardiac Surgery

Abstract Background Coagulatory alterations are common after pediatric cardiac surgery and can be addressed with point-of-care (POC) coagulation analysis. The aim of the present study is to evaluate a preventive..

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Use of colloids and crystalloids for perioperative clinical infusion management in cardiac surgery patients and postoperative outcomes: a meta-analysis

Abstract Background The optimal fluid management strategy for patients undergoing cardiac surgery was controversial regarding fluid volume and intraoperative fluid types. This study aimed to assess the correlation between colloids..

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Effect of preoperative autologous platelet-rich plasmapheresis on postoperative bleeding in patients undergoing heart valve surgery

Abstract Background: Cardiovascular surgeries often require deep hypothermic circulatory arrest and cardiopulmonary bypass (CPB), which can disrupt blood clotting and lead to excessive bleeding. Traditional treatments involve transfusing blood and blood..

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Is it time for the death knell of single-unit plasma?

Abstract Background and Objectives A plasma transfusion dose should be weight-based (10–20 mL/kg), which equates to three to four units in an average-sized adult; therefore, the transfusion of single units under..

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Associations Between Nonanemic Iron Deficiency and Postoperative Outcomes in Cardiac Surgery: A Systematic Review and Meta-Analysis

Abstract BACKGROUND: Preoperative screening for iron deficiency is a part of patient blood management protocols. This systematic review, meta-analysis, and meta-regression reviews the association between nonanemic iron deficiency and postoperative..

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A clinical comparison of glycol and water-based heater-cooler systems for cardiopulmonary bypass

Abstract Introduction While newer heater-cooler technologies using ethylene glycol-based (GB) solutions during cardiothoracic surgery have become commercially available, there is a paucity of clinical data describing their effectiveness during cardiopulmonary..

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Antepartum hemorrhage due to placenta previa with autologous transfusion: A case report

Abstract Introduction and importance Bleeding during pregnancy or during  can cause significant morbidity and mortality for the mother and baby, this can be overcome by performing a  (C-section) and . Although blood transfusions..

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In vitro protamine addition for coagulation assessment using TEG 6s system during cardiopulmonary bypass: a pilot study

Abstract Objective Systemic heparinization during cardiopulmonary bypass (CPB) can significantly affect thromboelastography (TEG). This study investigated the feasibility of adding protamine in vitro to allow assessment of coagulation status using the..

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The Relationship Between Transfusion in Cardiac Surgery Patients and Adverse Outcomes

Abstract Objectives To understand if red blood cell (RBC) transfusions are independently associated with a risk of mortality, prolonged , or infectious, cardiac, or renal morbid outcomes. Design A retrospective review...

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Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

Abstract Background Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of..

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Impact of a cell salvage device on blood transfusions to dogs undergoing surgery at a referral veterinary hospital

Abstract Objective To determine the number of homologous blood transfusions received by canine surgical patients after introducing a cell salvage device (CSD), trends in surgeries requiring blood transfusion, and the..

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Effects of Fibrinogen Concentrate Supplementation on Postoperative Bleeding in Infants Undergoing Complex Cardiac Surgery

Abstract The use of allogeneic blood products to restore hemostasis during pediatric cardiac surgery is associated with major risks. Consequently, there has been a growing interest in new patient blood..

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Evaluation of staged autologous blood transfusion during extracorporeal membrane oxygenation decannulation: A retrospective study

Abstract Background Clinical blood resources are scarce and autologous blood transfusion for extracorporeal membrane oxygenation (ECMO) withdrawal is less studied. Objectives To assess the use of staged  during  decannulation. Methods The study..

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Comparison of red blood cell transfusions and hemostatic transfusions and their relation to thromboses in pediatric patients receiving extracorporeal membrane…

Abstract Objective To evaluate the association of RBC transfusions with thrombosis in pediatric patients on extracorporeal membrane oxygenation (ECMO) and compare this with the transfusion of other blood products and..

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Blood Management: A Current Opportunity in Perioperative Medicine

Abstract The purpose of this viewpoint is to provide awareness of the current opportunities to enhance a high-value care approach to blood product transfusion. It provides a historical context to..

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Non-invasive prediction of massive transfusion during surgery using intraoperative hemodynamic monitoring data

Abstract Objective Failure to receive prompt  leads to severe complications if massive  occurs during surgery. For the timely preparation of blood products, predicting the possibility of massive transfusion (MT) is essential to..

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Outcomes associated with absent blood product utilization in Jehovah’s witness patients compared to the standard of care in cardiac surgery:…

Abstract Introduction For Jehovah’s Witness (JW) patients requiring cardiac surgery, various strategies such as preoperative use of erythropoietin stimulating agents (ESAs), intravenous iron (IVI), and non-pharmacologic interventions have emerged to..

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The Association of Oxygen Delivery and Transfusion on Cardiopulmonary Bypass with Acute Kidney Injury

Abstract Objectives To estimate whether the association of transfusion and acute kidney injury (AKI) has a threshold of oxygen delivery below which transfusion is beneficial but above which it is..

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Impact of a bundle of care (intravenous iron, erythropoietin and transfusion metabolic adjustment) on post-operative transfusion incidence in cardiac surgery:…

Abstract Background Red blood cell (RBC) transfusions are frequent in patients after cardiac surgery. This study assessed whether a bundle of care including pre-operative and post-operative administration of  (EPO) with intravenous..

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Delayed cold-stored vs. room temperature stored platelet transfusions in bleeding adult cardiac surgery patients—a randomized multicentre pilot study (PLTS-1)

Abstract Background Platelets stored at 1–6 °C are hypothesized to be more hemostatically active than standard room temperature platelets (RTP) stored at 20–24 °C. Recent studies suggest converting RTP to cold-stored platelets..

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Antithrombin restriction in extracorporeal membrane oxygenation support (ARES): A multidisciplinary approach

Abstract Background:   Antithrombin (AT) replacement is occasionally utilized in the setting of extracorporeal membrane oxygenation (ECMO)-associated heparin resistance. Although past studies emphasized the high costs and limited clinical benefit..

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A precise blood transfusion evaluation model for aortic surgery: a single-center retrospective study

Abstract Cardiac aortic surgery is an extremely complicated procedure that often requires large volume blood transfusions during the operation. Currently, it is not possible to accurately estimate the intraoperative blood..

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Factor Eight Inhibitor Bypassing Activity as First-line Therapy for Coagulopathy in Cardiac Surgery

Abstract Objectives To compare the outcomes of factor eight inhibitor bypassing activity (FEIBA) versus fresh frozen plasma (FFP) as the primary treatment for postoperative coagulopathy in patients undergoing cardiac surgery...

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Platelet-Rich Plasma Sequestration in Cardiac Surgery in a Jehovah's Witness

Abstract JEHOVAH'S WITNESSES (JW) refuse allogeneic blood transfusions because of their religious beliefs, a situation that poses significant challenges in the context of cardiac surgery, given that bleeding-related complications may..

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Acute normovolemic hemodilution in cardiac surgery: Rationale and design of a multicenter randomized trial

Abstract Background Minimizing the use of blood component can reduce known and unknown  risks, preserve blood bank resources, and decrease healthcare costs. Red Blood Cell (RBC) transfusion is common after cardiac..

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Conventional versus minimally invasive extra-corporeal circulation in patients undergoing cardiac surgery: A randomized controlled trial (COMICS)

Abstract Introduction The trial hypothesized that minimally invasive extra-corporeal circulation (MiECC) reduces the risk of serious adverse events (SAEs) after cardiac surgery operations requiring extra-corporeal circulation without circulatory arrest. Methods..

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