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Implementation of a Multidisciplinary Team for Initiation of Extracorporeal Cardiopulmonary Resuscitation in Patients Presenting After Out-of-hospital Cardiac Arrest

Abstract Objectives Patents with out-of-hospital cardiac arrest (OHCA) are at high risk of death or poor neurologic recovery if spontaneous circulation is not rapidly restored. Emergent mechanical circulatory support with..

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Obesity and Venoarterial Extracorporeal Membrane Oxygenation Outcomes: The Plot Thickens

Abstract We read with great interest a recent article on the association between body mass index (BMI) and outcomes in patients supported by venoarterial extracorporeal membrane oxygenation (VA-ECMO). In a review..

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Use of the measurement tools of TeamSTEPPS®: a scoping review

Abstract Background TeamSTEPPS® (Team Strategies and Tools to Enhance Performance and Patient Safety) is an evidence-based program developed to train healthcare professionals working in any environment where communication and teamwork are..

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Survey of Extracorporeal Life Support Application in Lung Transplantation

Abstract Introduction Lung transplantation has been evolving since its inception in 1963. Over recent years, literature has suggested a shift in the perioperative strategy of mechanical support toward extracorporeal membrane..

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Does methylene blue improve outcomes in patients with post-cardiac surgery vasoplegic syndrome?

Abstract OBJECTIVES A best evidence topic was written according to a structured protocol described in ICVTS. The question addressed was ‘In patients with vasoplegic syndrome following cardiac surgery with cardiopulmonary bypass,..

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Application of a novel extracorporeal membrane oxygenation system in awake Hu sheep under various durations

Abstract Background Extracorporeal membrane oxygenation (ECMO) provides effective support for respiratory and circulatory functions and stands as an essential means in the management of life-threatening conditions. This study aimed to..

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Incidence of neutrophil extracellular traps (NETs) in different membrane oxygenators: pilot in vitro experiments in commercially available coated membranes

Abstract Neutrophil extracellular traps (NETs) were detected in blood samples and in cellular deposits of oxygenator membranes during extracorporeal membrane oxygenation (ECMO) therapy and may be responsible for thrombogenesis. The..

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Blood Purification Membranes Used in Liquid–Gas Environments: Artificial Lungs

Abstract Extracorporeal membrane oxygenation (ECMO), the key component of which is a membrane oxygenator, known as the artificial lung, could provide irreplaceable respiratory support for patients with cardiopulmonary failure. The..

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Anticoagulation Monitoring Strategies During Extracorporeal Membrane Oxygenation (ECMO) Therapy – Differences Between Simultaneously Obtained Coagulation Tests: A Retrospective Single-Center Cohort…

Abstract Introduction During extracorporeal membrane oxygenation (ECMO) systemic anticoagulation with unfractionated heparin (UFH) is standard-of-care. However, there is uncertainty regarding optimal anticoagulation monitoring strategies. Methods We retrospectively investigated venovenous and..

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From GPT to DeepSeek: Significant gaps remain in realizing AI in healthcare

Abstract Introduction On January 27, 2025, DeepSeek-R1, a new Generative AI model, was introduced and rapidly gained adoption, taking over the user market to become the No.1 downloaded AI app , , ...

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Daily Surveillance Blood Cultures in Children Supported With Extracorporeal Membrane Oxygenation: Single-Center, Retrospective Cohort Study, 2021–2023

Abstract Objective:  Diagnosing bloodstream infections (BSIs) in patients on extracorporeal membrane oxygenation (ECMO) can be challenging due to circuit-controlled temperature, altered hemodynamics, and questionable reliability of inflammatory markers in critically..

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Perioperative extracorporeal membrane oxygenation in neonates with transposition of the great arteries: 15 years of experience

Abstract OBJECTIVES Extracorporeal membrane oxygenation (ECMO) can act as a bridge to recovery in both pre- and postoperative patients with transposition of the great arteries (TGA). However, literature on its..

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Parallel Venovenous Extracorporeal Membrane Oxygenation Circuits During Bridge-to-Lung Transplantation

Abstract Venovenous (VV) extracorporeal membrane oxygenation (ECMO) supports end-organ oxygen delivery in patients with refractory respiratory failure. Physical therapy (PT) while on ECMO provides conceptual benefits of strength and conditioning...

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Impact of Multistage Cannula on Recirculation in Various Venovenous Extracorporeal Membrane Oxygenation Cannulation Strategies

Abstract We aimed to compare recirculation of venovenous extracorporeal membrane oxygenation (V-V ECMO) administered with various cannula placements for femoro-femoral (F-F) and femoro-jugular (F-J) configurations in patients with respiratory failure...

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The first case of central Y–Y extra-corporeal membrane oxygenation system in a pediatric patient

Abstract The mechanical circulatory support (MCS) for pediatric patients with severe acute heart failure and poor pulmonary conditions is challenging. Herein, we report the first pediatric case of successfully treated..

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ECMO for the pregnant and peripartum patient: A practical review of indications, unique management considerations, and an approach framework

Abstract The use of extracorporeal membrane oxygenation (ECMO) to support the pregnant patient and fetus requires a complex decision-making process. Peripartum ECMO requires coordinated and informed decision-making between an interdisciplinary..

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Treatment time limit for successful weaning from veno‐arterial extracorporeal membrane oxygenation in cardiogenic shock

Abstract Aims Knowing the upper time limit for successful weaning from temporary mechanical circulatory support in cardiogenic shock will help with decision‐making regarding advanced heart failure (HF) therapy or considering..

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Impact of Cannulation Strategy and Extracorporeal Blood Flow on Recirculation During Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Introduction Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is increasingly used in the treatment of severe respiratory failure. Despite a significant increase in the worldwide use of extracorporeal lung assist..

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Implementation of Bundled Interventions to Reduce Surgical Site Infections in Pediatric Patients Undergoing Cardiothoracic Surgery: A Quality Improvement Project

Abstract Pediatric patients undergoing cardiothoracic surgery are at increased risk for health care–associated infections, especially surgical site infections (SSIs). Delayed sternal closures are associated with prolonged lengths of stay and..

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Normothermic Crystalloid Polarizing Cardioplegia Improves Systolic and Diastolic Function in a Porcine Model of Cardiopulmonary Bypass

Abstract Background/Objectives: Previously, we showed that blood-based polarizing cardioplegia exerted beneficial cardioprotection during hypothermic ischemia; however, these positive effects of blood-based polarizing cardioplegia were reduced during normothermic ischemia compared to..

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The effects of changes in thrombocyte indices, on-on-pump time on prognosis in open heart surgery

Abstract Extracorporeal perfusion systems utilized in open-heart surgeries with cardiopulmonary bypass can affect multiple body systems. The primary adverse effects of Extracorporeal Perfusion Systems (EPS) on the hematological system include..

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Extracorporeal membrane oxygenation in pregnancy and the post-partum period: a systematic review and meta-analysis

Abstract Objective There is an increase in the application data of Extracorporeal Membrane Oxygenation (ECMO) in perinatal women, particularly since the outbreak of coronavirus disease 2019. Therefore, we reviewed publications..

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Developing active learning activities for didactic perfusion courses

Abstract Background In the world of academia, traditional lecturing has been the most common pedagogical approach for centuries. However, it can create an environment for students to be passive learners..

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Congenital cardiac surgical simulation: bridging global workforce gaps and optimizing outcomes

Abstract Reaching competency in congenital heart surgery (CHS) requires lengthy and rigorous training. Due to patient safety, time limitations, and procedural complexity, the intraoperative setting is not ideal for technical..

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Advances in understanding the effects of cardiopulmonary bypass on gut microbiota during cardiac surgery

Abstract Cardiopulmonary bypass (CPB) is an indispensable technique in cardiac surgery; however, its impact on gut microbiota and metabolites remains insufficiently studied. CPB may disrupt the intestinal mucosal barrier, altering..

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Effects of noradrenaline and phenylephrine on cerebral oxygen saturation during cardiopulmonary bypass in cardiac surgery

Abstract Cardiopulmonary bypass (CPB) in cardiac surgery is associated with a high risk of postoperative neurological complications. Perioperative use of vasopressors is common to counteract arterial hypotension in this setting...

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The influence of cardiopulmonary bypass residual volume processing technique on blood management in cardiac surgical patients

Abstract Background: Post-cardiopulmonary bypass (CPB) blood processing is an important component of blood management during cardiac surgery.    Purpose: The purpose of this study is to evaluate several methods of processing post-CPB..

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Acute aortic dissection during minimally invasive cardiac surgery: a case report

Abstract Background Management of acute aortic dissection (AAD) caused by retrograde perfusion through the femoral artery during minimally invasive cardiac surgery (MICS) remains controversial. We present a case of AAD..

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Direct Axillary Artery Cannulation as Standard Perfusion Strategy in Minimally Invasive Coronary Artery Bypass Grafting

Abstract Objective: Cardiopulmonary bypass (CPB) via the right axillary artery (RAA) has become an alternative perfusion strategy, especially in complex aortic procedures. This study delineates our technique and outcome with..

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Anti-platelet Factor 4 Antibody-Mediated Disorders: An Updated Narrative Review

Abstract Anti-platelet factor 4 (PF4) antibody-mediated disorders are a heterogeneous group of diseases characterized by the presence of highly pathogenic immunoglobulins G directed against PF4 and/or PF4/heparin complexes. These antibodies..

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