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Ethical Issues in Normothermic Regional Perfusion in Controlled Organ Donation After Determination of Death by Circulatory Criteria: A Scoping Review

Abstract Normothermic regional perfusion (NRP) is a surgical technique that can improve the quality and number of organs recovered for donation after the determination of death by circulatory criteria. Despite..

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Hemoadsorption in the Management of Septic Shock: A Systematic Review and Meta-Analysis

Abstract Background/Objectives: Septic shock remains a significant clinical challenge with consistently high mortality rates. Recent investigations have focused on the efficacy of CytoSorb® (CytoSorbents Corporation, Monmouth Junction, NJ, USA), an extracorporeal..

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Racial and Sex Disparities in Incidence, Risk Factors, and Outcomes of Neonatal Extracorporeal Life Support in the United States

Abstract The impact of race on extracorporeal life support (ECLS) availability, morbidity, and mortality remains poorly defined. We sought to define the impact of race/ethnicity, sex, and location on ECLS..

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A Novel, Interpretable Machine Learning Model to Predict Neurological Outcomes Following Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: We used machine learning models incorporating rich electronic medical record (EMR) data to predict  neurological outcomes after venoarterial extracorporeal membrane oxygenation (VA‑ECMO).   Methods: This was a retrospective..

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Continuous Kidney Replacement Therapies: Core Curriculum 2025

Abstract Critically ill patients that require kidney replacement therapy (KRT) are among the most ill and complex patients routinely encountered in the intensive care unit (ICU). Continuous KRT (CKRT) is..

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Extracorporeal membrane oxygenation after lung transplant: An ELSO registry analysis

Abstract Background The use of extracorporeal membrane oxygenation (ECMO) has expanded and is now widely applied to perioperative care in lung transplant. Respiratory failure after lung transplant is a clinical..

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Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial

Abstract Background The impact of intra-aortic balloon pump (IABP) on survival and successful bridging to heart replacement therapies (HRT) in patients with heart failure–cardiogenic shock (HF-CS) remains unclear. Objectives The..

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Evaluation of Plasma Biomarkers to Understand the Biology and Heterogeneity of Treatment Effect in Lower Tidal Volume Ventilation Facilitated by…

Abstract OBJECTIVES:  In patients with acute hypoxemic respiratory failure (AHRF), the use of lower tidal volume ventilation facilitated by veno-venous extracorporeal CO2 removal (vv-ECCO2R) does not improve clinical outcomes. The primary..

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A Retrospective Cohort Study of the Role of Palliative Care Consultation for Patients on Extracorporeal Membrane Oxygenation

Abstract Background Extracorporeal membrane oxygenation (ECMO) serves as a critical intervention for patients with severe cardiac and pulmonary dysfunction. Given the high rates of mortality and morbidity, as well as..

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Left Ventricular Unloading Is Associated With Lower Mortality in Patients With Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial recovery. The Impella unloads the left ventricle. This study aimed to..

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Differential Venous Drainage Mimicking Differential Oxygenation in Patients on Extracorporeal Life Support

Abstract This report presents a case series that introduces differential venous drainage (DVD) as an underrated complication arising from the hemodynamic impact of the extracorporeal life support (ECLS) circuit on..

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A Simulation Curriculum for Ground and Air ECMO Transport

Abstract Introduction: The use of extracorporeal membrane oxygenation (ECMO) for cardiopulmonary failure is increasing. ECMO transport teams are needed to expand patient access. Our goal was to design and implement a..

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Impact of implementing a nurse-led intraoperative cell saver service in reducing allogeneic red blood cell transfusions in Singapore General Hospital

Abstract Introduction Major perioperative blood loss often necessitates allogeneic blood transfusions, leading to adverse outcomes and straining healthcare resources. Intraoperative cell salvage (ICS) offers benefits like reduced adverse reactions, optimised blood..

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Axillary Artery Versus Femoral or Central Arterial Cannulation in Minithoracotomy Mitral Surgery: Is There a Difference in Early Outcomes?

Abstract Objective: Axillary artery cannulation techniques continue to improve and find application throughout cardiac surgery. Yet, early outcomes are poorly documented versus femoral or central arterial cannulation in right minithoracotomy..

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Staying in Place: In Vitro Comparison of Extracorporeal Membrane Oxygenation Cannula Fixation for Dislodgment Prevention

Abstract Background/Objectives: Secure large-bore cannula insertion is critical for effective extracorporeal membrane oxygenation (ECMO), as inadequate fixation can lead to complications such as infection, dislodgment, and life-threatening events. With inconsistent..

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Volatile anaesthetics and PFAS forever chemicals: A critical gap in environmental impact assessments

Abstract The environmental impact of volatile anaesthetics has traditionally been evaluated primarily in terms of their greenhouse gas contributions. This review broadens the discourse by exploring the ecological ramifications of..

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Patent foramen ovale: A variant of normal or a true congenital heart disease?

Abstract Foramen ovale plays a key role in foetal circulation, however it may remain patent after birth throughout the life. Its patency is so frequent in healthy people (27-35 %),..

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Essential principles for blood centrifugation

Abstract Currently, autologous platelet concentrates (APCs) are frequently used for soft- and hard-tissue regeneration, not only within the oral cavity, but also extra-orally including chronic wounds, burns, joints, dermatological conditions,..

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Direct Reinfusion of Unwashed Shed Autologous Blood During Thoracoabdominal Aortic Aneurysm Repair: A Retrospective Analysis

Abstract BACKGROUND:  This study’s purpose was to assess whether larger volumes of reinfused unwashed shed autologous blood (SAB) were associated with adverse events within 30 days for patients undergoing open..

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Practical prognostic tools to predict the risk of postoperative delirium in older patients undergoing cardiac surgery: visual and dynamic nomograms

Abstract Purpose Postoperative Delirium (POD) has an incidence of up to 65% in older patients undergoing cardiac surgery. We aimed to develop two dynamic nomograms to predict the risk of..

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Effects and trend of steroid dosage reduction during cardiac surgery: A three-year retrospective analysis at a tertiary medical center

Abstract Background Current adult cardiac surgery guidelines recommend against the routine use of prophylactic intravenous corticosteroids during cardiopulmonary bypass (CPB) due to concerns about myocardial injury, despite their potential to..

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A clinical comparison of the effects of six disposable cardiopulmonary bypass circuits on bleeding and coagulation: a quality assurance project

Abstract Purpose Cardiac surgery requiring cardiopulmonary bypass (CPB) is frequently complicated by excessive bleeding because of coagulopathy. Contact of blood with the CPB circuit is a major contributor. While several..

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Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes: A Prospective Clinical Study With 4-year…

Abstract Study design Prospective Clinical Study. Objective Allogeneic blood transfusion (ABT) is the current standard of blood replenishment for metastatic spine tumour surgery (MSTS) despite known complications. Salvaged blood transfusion..

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Industry payments and implicit bias in cardiothoracic surgery: Difference in industry payments to cardiothoracic surgeons by gender

Abstract Objective Industry payments, as sources of revenue and prestige, may contribute to gender implicit bias. We examined industry payments to cardiothoracic surgeons to determine differences with respect to gender..

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How we would use Cardiac Enhanced Recovery After Surgery: What we would do for ourselves across the perioperative period during…

Abstract Enhanced Recovery After Cardiac Surgery (ERACS) programs have grown from their humble beginnings as a ‘Fast-track recovery’ pathway which was first described in 1994, and have now evolved into..

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Development and validation of a checklist for cardiopulmonary bypass

Abstract Introduction: Risk prevention protocols related to patient care have been developed to reduce the incidence of adverse events in health care services. Cardiopulmonary bypass (CPB) can trigger several complications,..

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Insights from autopsy-initiated pathological studies of the pathogenesis and clinical manifestations of atherosclerosis and ischemic heart disease: Part I. Atherosclerosis

Abstract Context Ischemic heart disease (IHD) due to coronary atherosclerosis constitutes the leading cause of morbidity and mortality worldwide. This review was undertaken to document the historical basis for our..

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Monitoring Hemostatic Function during Cardiac Surgery with Point-of-Care Viscoelastic Assays: A Narrative Review

Abstract Bleeding is a well-known and severe complication of cardiac surgery. Cardiopulmonary bypass, along with heparinization and hemodilution, is thought to affect all pathways of the hemostatic process, leading to..

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In Silico Analysis of Pulsatile Flow Veno-Arterial Extracorporeal Membrane Oxygenation on Human Aorta Model

Abstract Electrocardiogram (ECG)—synchronized pulsatile veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is a recent development in extracorporeal therapy for patients with severe cardiogenic shock. Although preclinical studies have shown benefits of..

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Scavenger endothelial cells alleviate tissue damage by engulfing toxic molecules derived from hemolysis

Abstract Hemolysis induces tissue damage by releasing cellular contents into the plasma. It is widely accepted that hemolysis-derived toxic molecules are cleared by macrophages or metabolized in hepatocytes. In zebrafish,..

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