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Goal-directed Perfusion to Reduce Acute Kidney Injury After Pediatric Cardiac Operation

Abstract Background Although goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) has been discussed extensively in adult studies, no pediatric indexed oxygen delivery (Do2i) thresholds are universally accepted, and no pediatric..

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Real-time blood gas management: evaluating quantum perfusion system’s accuracy against a standard blood gas analysis in CPB

Abstract Background Continuous blood gas monitoring (CBGM) during cardiopulmonary bypass (CPB) is essential for maintaining optimal patient outcomes, enabling rapid responses to critical fluctuations in blood gas parameters. This non-inferiority..

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Outcomes of Neonatal Cardiac Surgery: A European Congenital Heart Surgeons Association Study

Abstract Background We evaluated outcomes of neonatal cardiac surgery at hospitals affiliated with the European Congenital Heart Surgeons Association (ECHSA). Methods All patients ≤30 days of life undergoing a cardiac..

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Understanding what leaders can do to facilitate healthcare workers’ feeling valued: improving our knowledge of the strongest burnout mitigator

Abstract Aim Feeling valued is a striking mitigator of burnout yet how to facilitate healthcare workers (HCWs) feeling valued has not been adequately studied. This study discovered factors relating to HCWs..

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Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery

Abstract Importance  Excessive bleeding is a common and prognostically important complication of cardiac surgery. For bleeding related to coagulation factor deficiency, frozen plasma is the most used therapy. Preliminary trials indicate..

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Exploring the Role of Immersive Virtual Reality Simulation in Health Professions Education: Thematic Analysis

Abstract Background: Although technology is rapidly advancing in immersive virtual reality (VR) simulation, there is a paucity of literature to guide its implementation into health professions education, and there are..

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Diagnosing Nosocomial Infections During Pediatric Extracorporeal Membrane Oxygenation

Abstract Nosocomial infections are one of the most frequent complications of extracorporeal membrane oxygenation (ECMO) and are associated with increased mortality (). Bloodstream infections present a particular problem because of..

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Enhancing the quality of surgical care through improved patient handover processes

Abstract Surgical handover remains a high-risk process with no gold standard for practice despite 20 years of available guidance. Variability in practice is common, and poorly performed handover poses significant,..

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Cardiac myxoma: a comprehensive review

Abstract Heart tumours are a diverse group of tumours that may present with symptoms or be discovered incidentally when a patient is being evaluated for a physical or seemingly unrelated..

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Adjunctive Fresh Frozen Plasma Versus Adjunctive Cryoprecipitate in Cardiac Surgery Patients Receiving Platelets for Perioperative Bleeding

Abstract Objective(s) This study was designed to assess the relative association between adjunctive fresh frozen plasma (FFP) or adjunctive cryoprecipitate and morbidity and mortality in cardiac surgery patients receiving platelets..

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Cerebral Hemodynamic Monitoring via Transcranial Doppler Ultrasound and Near-Infrared Spectroscopy for Risk-Stratified Pediatric Cardiac Surgery Patients

Abstract Background The objective of this study was to evaluate mean cerebral blood flow velocity, gaseous microemboli (GME) counts, regional cerebral oxygen saturation (rSO2), and clinical outcomes using multimodality neuromonitoring..

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Sepsis-Extracorporeal Membrane Oxygenation Score in Patients Receiving Extracorporeal Membrane Oxygenation Support for Sepsis

Abstract Predictive scoring systems for adult patients receiving extracorporeal membrane oxygenation (ECMO) support for sepsis have not been yet reported. Based on the Chinese Society of ExtraCorporeal Life Support (CSECLS)..

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Effect of extracorporeal circulation on structure of main components of animal plasma – ATR-IR and 2D-COS studies: Part I

Abstract Every year, more and more adults and children with severe cardiac and/or respiratory failure require connection to extracorporeal circulation (ECC). Despite a life-saving role in emergency settings, the use..

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Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry

Abstract BACKGROUND: A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated favorable outcomes in hearts recovered..

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Establishment and validation of a nomogram of postoperative delirium in patients undergoing cardiac surgery: a retrospective study of MIMIC-IV

Abstract Objective To establish a nomogram for predicting the occurrence of postoperative delirium (POD) in patients undergoing cardiac surgery. Materials and methods Data from 5379 patients were retrieved from the..

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Sex-related differences in systemic inflammatory response and outcomes after cardiac surgery and cardiopulmonary bypass

Abstract OBJECTIVES Differences in inflammatory responses between men and women may contribute to sex disparities in cardiac surgery outcomes. We investigated how sex differences influence systemic inflammatory response syndrome (SIRS)..

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Practical Considerations for Extracorporeal Membrane Oxygenation Use During Orthotopic Liver Transplantation

Abstract Patients undergoing liver transplantation infrequently require extracorporeal membrane oxygenation (ECMO) support. However, when ECMO is required in the peritransplant period, several key considerations are required to maximize the efficacy..

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Vasoplegia in Cardiac Surgery: A Systematic Review and Meta-analysis of Current Definitions and Their Influence on Clinical Outcomes

Abstract Objectives To identify differences in the reported vasoplegia incidence, intensive care unit (ICU) length of stay (LOS), and 30-day mortality rates as influenced by different vasoplegia definitions used in..

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Fluid management in adult patients undergoing venoarterial extracorporeal membrane oxygenation: A scoping review

Abstract Background The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) as a cardiocirculatory support has tremendously increased in critically ill patients. Although fluid therapy is an essential component of the..

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Summary of the best evidence for the management of kinesiophobia in patients after cardiac surgery

Abstract Background This study aimed to systematically search for relevant evidence on the management of kinesiophobia in patients after cardiac surgery both home and abroad. The evidence was evaluated and..

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Carboxyhemoglobin and Methemoglobin as Biomarkers of Hemolysis and Mortality in Acute Respiratory Distress Syndrome Treated by Veno-Venous Extracorporeal Membrane Oxygenation

Abstract BACKGROUND:  Critically ill patients who receive circulatory or respiratory assist using extracorporeal membrane oxygenation (ECMO) may develop hemolysis, which can complicate the delivery of supportive care and be a..

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Circular Shunt: A Loop Not to Be Ignored

Abstract A circular shunt, initially described by Shone et al. in 1962, refers to abnormal blood recirculation through complete intracardiac or intra- and extracardiac communications, bypassing the capillary beds. This..

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Left Ventricular Unloading Using Intra-aortic Entrainment Pumping Before Reperfusion Reduces Post-AMI Infarct Size

Abstract Background Anterior myocardial infarction standard of care prioritizes swift coronary reperfusion. Recent studies show left ventricular (LV) unloading with transvalvular axial flow pumps for 30 minutes before reperfusion (vs..

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Total bilirubin as a marker for hemolysis and outcome in patients with severe ARDS treated with veno-venous ECMO

Abstract Background Hemolysis is a common complication in critically ill patients with sepsis, acute respiratory distress syndrome (ARDS) or therapy with extracorporeal membrane oxygenation (ECMO). Heme degradation product bilirubin might..

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The impact of thyroid function on surgical prognosis in patients undergoing cardiac and major vascular surgeries

Abstract Objective This study aims to elucidate the relationship between thyroid function and surgical prognosis in patients undergoing cardiac and major vascular surgeries. Methods A retrospective cohort study was conducted..

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Prothrombotic Microvesicle Generation in Pediatric Cardiopulmonary Bypass: A Pilot Observational Study

Abstract Over 10% of children develop thrombosis after cardiac surgery for congenital heart disease. Children with a single ventricle physiology have the highest risk of thrombosis associated with increased length..

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Prevalence, Risk Factors, and Outcomes of Hospital-Acquired Infections in Children After Congenital Heart Surgery

Abstract Background Hospital-acquired infections (HAIs) are associated with morbidity and mortality in children following congenital cardiac surgery. Our center performs approximately 200 congenital surgeries a year, but infection rates and..

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Assay of cardiopulmonary bypass system for porcine alveolar macrophages removing GFP-E. coli from erythrocyte surfaces

Abstract While it is established that complement receptor molecules on the surface of erythrocytes are crucial for the clearance of immune complexes in the body, the molecular mechanisms underlying the..

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Awake veno-venous extracorporeal membrane oxygenation: practical aspects and considerations

Abstract Veno-venous extracorporeal membrane oxygenation (ECMO) is a life-saving technique in the armamentarium of critical care medicine. It involves extracorporeal blood circulation outside the body, providing temporary respiratory support while..

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Association of carboxyhemoglobin and methemoglobin levels with hemolysis during extracorporeal membrane oxygenation

Abstract Introduction: Hemolysis, characterized by increased carboxyhemoglobin (COHb) and methemoglobin (MetHb) levels, is a complication of extracorporeal membrane oxygenation (ECMO). Methods: This prospective single-center study aimed to investigate the correlation..

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