Abstract Objectives: This study aimed to measure the incidence of postoperative delirium (POD) after aortic arch surgery with hypothermic circulatory arrest (HCA), compare it to cardiac surgeries not requiring HCA, and..
Read MoreAbstract Background Immediate initiation of extracorporeal membrane oxygenation (ECMO) has not demonstrated benefit in individuals diagnosed with cardiogenic shock based on the presence of hypotension. The relationship between other hemodynamic..
Read MoreAbstract Midazolam is a commonly used sedative for patients on extracorporeal membrane oxygenation (ECMO). However, its long context-sensitive half-life is of concern. Remimazolam may be a suitable alternative. This study..
Read MoreAbstract Importance Acute kidney injury (AKI) after cardiac surgery is a common and serious complication. Protein loading appears nephroprotective; thus, continuous hyperoncotic albumin infusion may impact AKI following high-risk cardiac surgery...
Read MoreAbstract Solutions to reduce the need for systemic anticoagulation during extracorporeal life support would improve safety and utility. The study objective was to evaluate the safety and efficacy of a..
Read MoreAbstract BACKGROUND Cardiopulmonary bypass (CPB) is a life-support technology widely used in surgery. Review articles reflect research advances in a certain topic or field within a certain period of time...
Read MoreAbstract Introduction Cardiac surgery in infants often triggers a severe inflammatory response. The role of biomarkers in predicting clinical outcomes in this group of patients has been debated in the..
Read MoreAbstract Objective To investigate the impact of body mass index (BMI) on neurologic outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) Design Retrospective observational study Setting Single center Participants Adults Interventions..
Read MoreAbstract OBJECTIVES Chronic kidney disease can develop as a long-term complication after cardiac surgery—a condition associated with increased risk of new cardiovascular events, readmissions and mortality. Diagnosis is often delayed,..
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged as a promising intervention for refractory cardiac arrest, with potential benefits in survival and neurological outcomes. However, the impact of ECPR’s rapid,..
Read MoreAbstract OBJECTIVES Acute kidney injury commonly complicates congenital heart surgery with cardiopulmonary bypass, increasing morbidity and mortality. This study aimed to evaluate risk factors for postoperative acute kidney injury and..
Read MoreAbstract Background: Population pharmacokinetics (PK) models could provide specific references for the formulation of personal drug delivery protocols, however, there is no population PK study of tranexamic acid (TXA) have been..
Read MoreAbstract Background Survival for hypoplastic left heart syndrome (HLHS) and variants has improved over the past 4 decades; however, survival remains low compared with other forms of congenital heart disease...
Read MoreAbstract Objectives Age is the main determinant for mortality in patients requiring postcardiotomy extracorporeal membrane oxygenation (PC-ECMO), but strategies to reverse this trend are unknown. This study investigates PC-ECMO outcomes..
Read MoreAbstract Introduction: Indexed oxygen delivery (DO₂i) is a critical parameter in cardiopulmonary bypass (CPB) management. Traditional goal-directed perfusion (GDP) protocols use fixed DO₂i thresholds, typically derived from normothermic conditions. However,..
Read MoreAbstract Background The microaxial flow pump (mAFP) improves survival in selected patients with ST-segment elevation myocardial infarction–induced cardiogenic shock (STEMI-CS). Understanding the impact on cardiac output (CO), cardiac power output..
Read MoreAbstract Background Recent studies demonstrated satisfactory results of del Nido cardioplegia in minimally invasive cardiac surgery (MICS). We aimed to evaluate the efficacy of our modified “bloodless” del Nido cardioplegia..
Read MoreAbstract Regional cerebral oxygen saturation (rSO2) is used to monitor cerebral perfusion with emerging evidence that optimization of rSO2 may improve neurological and non-neurological outcomes. To manipulate rSO2 an understanding of the..
Read MoreAbstract OBJECTIVES This study determines the microplastic (MP) levels, dimension, shape, and chemical composition generated from conventional cardiopulmonary bypass and minimally invasive extracorporeal circulation (MiECC) circuits. METHODS In vitro conventional and..
Read MoreAbstract Purpose The purpose of this systematic review was to identify the efficacy of cell salvage in adult and pediatric spinal surgery. Methods A comprehensive systematic review of four biomedical..
Read MoreAbstract Microstructural imaging enables researchers to visualise changes in the arterial wall, allowing for (i) a deeper understanding of the role of specific components in arterial mechanics, (ii) the observation..
Read MoreAbstract Background Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic hemodilution [ANH]) is a blood-conservation technique..
Read MoreAbstract After cardiac arrest, restoration of circulation is the first step toward survivorship. Extracorporeal CPR (ECPR), the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) to restore circulation, is increasingly being..
Read MoreAbstract Purpose Clinicians presume a relationship between the management of blood pressure during cardiac surgery and postoperative morbidity and mortality. With limited evidence to inform practice, we surveyed Canadian cardiac..
Read MoreAbstract Aim To identify the factors associated with postoperative complications within the first 24 h among individuals who have undergone open-heart surgery. Design A cross-sectional study. Methods The participants were 192..
Read MoreAbstract Acute kidney injury (AKI) is a frequent and severe problem following heart surgery, particularly in procedures involving cardiopulmonary bypass (CPB). This research investigates the Randomized Controlled Trial (RCT) on..
Read MoreAbstract We investigated echocardiographic and hemodynamic effects of intraaortic balloon pump (IABP) in 26 patients with cardiogenic shock on veno-arterial membrane oxygenation (VA ECMO). Our study demonstrated an 8.1% increase..
Read MoreAbstract Introduction Prolonged extracorporeal circulation time is known to cause intraoperative and postoperative bleeding, but the underlying mechanism is not fully understood. In this study, we analyzed the effects of..
Read MoreAbstract Bleeding and transfusion during cardiac surgery are major sources of complications. Surgery and cardiopulmonary bypass can induce coagulopathy, including platelet dysfunction. Desmopressin has been shown to reduce bleeding and..
Read MoreReport of the Portable Ex Vivo Organ Perfusion Workforce Survey: Staffing Models and Clinical Trends
Abstract Historically, organs recovered for transplant have been transported using static cold preservation. However, newer portable ex vivo organ perfusion (PEVOP) strategies allow warm organ perfusion during transport. Although PEVOP is a..
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