Abstract Introduction Femoral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is used as an ultima ratio to maintain circulation in patients with refractory cardiorespiratory failure, but is also associated with vascular and..
Read MoreAbstract Extreme prematurity carries a high burden of morbidity and mortality. The artificial placenta is an emerging therapy that has the potential to improve outcomes in these patients. However, current..
Read MoreAbstract Objectives Systemic inflammatory response syndrome (SIRS) is a common complication following cardiopulmonary bypass (CPB), associated with increased mortality. We assessed the relationship between indexed oxygen delivery (DO2i) during CPB..
Read MoreAbstract Objective Overdiagnosis occurs when abnormalities meeting diagnostic criteria would remain asymptomatic if undiagnosed. Cases initially identified through digital diagnostic tools but later recognised as overdiagnosis are referred to as..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) is utilized in critically ill neonates with severe cardiopulmonary failure. Hemolysis is a potential complication and is associated with significantly increased morbidity and mortality...
Read MoreAbstract Background Active mechanical circulatory support (MCS) is associated with high complication rates. Reducing device-related complications may improve outcomes in patients with infarct-related cardiogenic shock (AMI-CS). This study aims to..
Read MoreAbstract Venovenous extracorporeal membrane oxygenation (VV ECMO) has become an increasingly preferred modality for respiratory support in neonates and infants under 10 kg, driven by a growing recognition of its..
Read MoreAbstract Objectives To compare effectiveness and safety of rescue therapy approach with recombinant Factor VII activated (rFVIIa) for refractory bleeding in cardiac surgery compared with a propensity-score-matched control group at..
Read MoreAbstract Background Venovenous extracorporeal membrane oxygenation (VV-ECMO) is often used for lung rest in critically ill patients, including pregnant patients. Objectives We aimed to determine how pregnant and non-pregnant patients..
Read MoreAbstract Extracorporeal Membrane Oxygenation (ECMO) is a life-saving cardiopulmonary support for patients with acute heart failure. However, the process of weaning from veno-arterial (V-A) ECMO remains complex and risky. We..
Read MoreSimulation-Based Education for Extracorporeal Membrane Oxygenation and Strategies for Implementation
Abstract Simulation-based education (SBE) in health care is expanding in both scope and relevance. As on-the-job training is challenging in extracorporeal membrane oxygenation (ECMO), SBE features strongly in its curricula,..
Read MoreAbstract Background Intra-aortic balloon pump (IABP) implantation in the perioperative period of cardiac surgery is an auxiliary treatment for cardiogenic shock. However, there is a lack of effective prediction models..
Read MoreAbstract Objectives To evaluate the effectiveness of levosimendan in promoting weaning from veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with refractory cardiogenic shock through a meta-analysis of clinical trials. Design Systematic review..
Read MoreAbstract Objective:This study aimed to evaluate school-age neurodevelopmental outcomes among children with single ventricle heart disease who underwent neonatal Norwood operation with regional cerebral perfusion compared to deep hypothermic circulatory..
Read MoreAbstract Objective To determine the relationship between intraoperative decreased renal and cerebral oxygen saturation, as measured using near-infrared spectroscopy (NIRS), and cardiac surgery-associated acute kidney injury (CSA-AKI) in adults. Methods..
Read MoreAbstract This study analyzed the outcomes of neonates undergoing a second run of extracorporeal membrane oxygenation (ECMO) to determine whether there is a benefit to a repeated run. We used..
Read MoreAbstract This review examines the clinical data and basic science research to evaluate the potential of the Selective Cytopheretic Device (SCD) in mitigating Extracorporeal Membrane Oxygenation (ECMO)-associated inflammation. In brief,..
Read MoreAbstract Allogeneic red blood cells (RBCs) are commonly used for cardiopulmonary bypass (CPB) circuit priming in congenital heart surgery. While convection-based pre-bypass ultrafiltration (PBUF) corrects acid–base, electrolyte, and metabolite imbalances,..
Read MoreAbstract The COVID-19 pandemic has revealed that the impact of SARS-CoV-2 infection extends well beyond the acute phase, with long-term sequelae affecting multiple organ systems, most notably, the cardiovascular system...
Read MoreAbstract BACKGROUND: Major bleeding after cardiac surgery is still a relatively common complication, requiring red blood cell (RBC) transfusions and use of procoagulants. The existing guidelines recommend a bleeding management..
Read MoreAbstract Background Maintaining adequate oxygen delivery during cardiopulmonary bypass (CPB)-assisted cardiac surgery is crucial, but hyperoxia has been suggested to cause organ injury. We compared the effects of restrictive vs liberal oxygenation..
Read MoreAbstract Decisions regarding veno-venous extracorporeal membrane oxygenation (vv-ECMO) in patients with acute respiratory distress syndrome (ARDS) are often based solely on clinical and physiological parameters, which may insufficiently reflect severity..
Read MoreAbstract The demand for homologous blood transfusions has reached an unprecedented level, driven by a declining donor population and the ever-increasing need for blood products. While significant advancements have been..
Read MoreAbstract Objectives: To evaluate the relationship between the duration of pre-extracorporeal membrane oxygenation (ECMO) mechanical ventilation and mortality in acute respiratory distress syndrome (ARDS) patients undergoing venovenous ECMO. Design: Retrospective..
Read MoreAbstract Cardiac surgery, particularly procedures involving cardiopulmonary bypass (CPB), is associated with a high risk of postoperative complications, including systemic inflammatory response syndrome (SIRS), postoperative atrial fibrillation (POAF), and infection...
Read MoreAbstract Objective To evaluate the robustness of randomized controlled trials (RCTs) investigating acute normovolemic hemodilution (ANH), a blood conservation strategy designed to reduce transfusion requirements, in cardiac surgery using the..
Read MoreAbstract Perioperative hyperglycemia is associated with increased morbidity and mortality. We report the findings of our quality improvement project on the use of an electronic insulin dosing calculator (EIC) to..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) supports patients with severe refractory cardiac or respiratory failure but managing residual circuit blood after weaning lacks consensus. After decannulation, the oxygenator and circuit retain..
Read MoreAbstract Introduction Limb loss after combat injury is a major factor for morbidity in combat casualties. Although tourniquets clearly save lives, they can result in prolonged ischemia in large scale..
Read MoreAbstract In humans, the transfer of respiratory gases between the atmosphere and living cells depends on their diffusion between lungs, blood, and cells, as well as their advective transport by..
Read More

















