Abstract Acute respiratory distress syndrome (ARDS) in pregnancy is rare but life-threatening. Extracorporeal membrane oxygenation (ECMO) has been used as rescue therapy in refractory cases, though evidence remains limited. This..
Read MoreAbstract Background Indirect calorimetry (IC) in patients receiving extracorporeal membrane oxygenation (ECMO) is complicated. This study presents a novel IC method for this population and compares energy expenditure (EE) from..
Read MoreAbstract Background Cardiac surgery with cardiopulmonary bypass (CPB) requires precise hemostasis management to limit postoperative bleeding. Fibrinogen, platelet count, and pro-coagulant factors guide transfusion decisions, yet Clauss fibrinogen measurement during..
Read MoreAbstract Background Perioperative hyperglycemia is common during cardiac surgery and has been linked to an increased risk of surgical site infections (SSIs). However, the benefits of perioperative tight glucose control..
Read MoreAbstract Background ECMO-associated coagulopathy is a common phenomenon in patients undergoing ECMO therapy. However, data on coagulation trajectories in the post ECMO decannulation period are limited. This study aimed to..
Read MoreAbstract Shear-induced platelet activation and receptor shedding in mechanical circulatory support (MCS) paradoxically increase risks of thrombosis and bleeding. Although flow cytometry commonly assesses platelet activation and receptor expression, correlations..
Read MoreAbstract Background The membrane oxygenator is a critical component of extracorporeal circulation (ECC), whose performance directly depends on its structural architecture. Differences in fiber geometry and winding patterns lead to..
Read MoreAbstract Ex situ normothermic machine perfusion (NMP) of the liver has emerged as a dynamic preservation strategy, enabling the maintenance of metabolic activity and assessment of grafts prior to transplantation. Prolonged..
Read MoreAbstract Objectives Exploratory laparotomy, when required as a treatment for abdominal complications of post–extracorporeal membrane oxygenation (ECMO) initiation, carries a high mortality rate that approaches 80% to 100%. However, studies..
Read MoreAbstract Background: Temporary mechanical circulatory support (t‑MCS) is increasingly used in fulminant myocarditis (FM), yet long‑term outcomes and risk factors remain poorly defined. Methods: From the FULLMOON international cohort..
Read MoreAbstract Objective: Extracorporeal membrane oxygenation (ECMO) has been used to provide pulmonary and circulatory support in patients with ongoing critical illness. Studies investigating whether an association exists between ECMO center-volume..
Read MoreAbstract Background: Harlequin syndrome, also referred to as differential hypoxemia or North South syndrome, is a critical yet underrecognized complication of venoarterial extracorporeal membrane oxygenation and hybrid configurations such as ECpella...
Read MoreAbstract Background The microaxial flow pump (mAFP) has demonstrated improved outcomes in selected patients with ST-segment elevation acute myocardial infarction and cardiogenic shock (STEMI-CS). However, its use has been associated..
Read MoreAbstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..
Read MoreAbstract Introduction Due to anticoagulation during Extracorporeal Membrane Oxygenation (ECMO), patients face a higher risk of bleeding. This study aimed to assess the correlation between anticoagulation assays and hemorrhage in..
Read MoreAbstract Objective To characterize in-hospital morbidity and mortality in patients undergoing cardiovascular surgery with and without cannabis use disorder (CUD) using a national database. Methods Between 2016 and 2018, 846,837..
Read MoreAbstract Background Deficiencies in non-technical skills (NTS) such as leadership and communication can lead to intraoperative inefficiency and error. However, the relationship between these skills and patient-level outcomes has yet..
Read MoreAbstract Background: Veno-venous extra-corporeal membrane oxygenation (ECMO) cannulations are mostly performed while patients are heavily sedated and mechanically ventilated. For patients with acute respiratory distress syndrome (ARDS), cannulating for ECMO while..
Read MoreAbstract Introduction Wearable sensing technologies incorporated into virtual reality (VR) headsets can provide a number of unique, previously hidden insights into individual and team learning and performance in complex environments...
Read MoreAbstract Background Hyperammonemia is a rare but serious cause of encephalopathy, commonly associated with hepatic dysfunction. However, non-hepatic hyperammonemia (NHHA) can arise due to impaired gastrointestinal transit, urease-producing organisms, and..
Read MoreAbstract Aim Erythrocytes from patients with thalassemia might be susceptible to hemolysis during recycling and washing. Therefore, autologous erythrocyte transfusion using erythrocytes from parturient women with thalassemia has been suggested..
Read MoreAbstract Objectives: Oxidative stress after cardiac surgery may disrupt the blood–brain barrier and contribute to postoperative delirium (POD). Although associations between oxidative stress and POD are recognized, whether vitamin C (VC)..
Read MoreAbstract Purpose of review Mechanical ventilation (MV) is central to the management of acute respiratory distress syndrome (ARDS). In refractory cases, veno-venous extracorporeal membrane oxygenation (VV-ECMO) can provide adequate gas..
Read MoreAbstract Background Delirium is an aetiologically nonspecific cerebral syndrome characterised by disturbances in consciousness, attention, perception, cognition, memory, psychomotor activity, emotion, and the sleep–wake cycle. It frequently occurs after cardiac..
Read MoreAbstract Background: Hemolysis, defined as the rupture of red blood cells (RBCs) with the release of hemoglobin into plasma, is a common concern during blood collection and extracorporeal circulation. Although..
Read MoreAbstract To the Editor: I wish to share the results of a retrospective observational correlation study I completed recently. While it is well established that the platelet count is negatively..
Read MoreSecuring data management systems in perfusion: A narrative review on cybersecurity and clinical risk
Abstract Background The increasing digitization of perfusion practice has led to the integration of advanced data management systems (DMS) that record and analyze intraoperative variables in real time. While these..
Read MoreAbstract Objective: Unfractionated heparin (UFH) is the most widely used anticoagulant during extracorporeal membrane oxygenation (ECMO). Optimal dosing of UFH for children undergoing ECMO is unknown, leading to suboptimal exposure...
Read MoreAbstract Microfluidic oxygenators promise to advance extracorporeal membrane oxygenation (ECMO) devices with enhanced hemodynamics and low prime volume. We are developing a silicon-based membrane oxygenator that will offer improved gas..
Read MoreAbstract Objectives: While potential risks for limb ischemia have been explored in studies of venoarterial extracorporeal membrane oxygenation (ECMO), they remain inadequately defined for patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR)...
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