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A derived and validated score to predict prolonged mechanical ventilation in patients undergoing cardiac surgery

Abstract Objectives Prolonged  after cardiac surgery imposes a significant burden on the patient in terms of morbidity as well as a financial burden on the hospital. We undertook a retrospective analysis..

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Intra-Aortic Balloon Pump Counterpulsation in the Post-Resuscitation Period is Associated with Improved Functional Outcomes in Patients Surviving an Out-of-Hospital Cardiac…

Abstract Background Despite advances in cardiopulmonary resuscitation, functional survival remains low after  (OOHCA).  (IABP) therapy has recently been shown to augment cerebral blood flow. Whether  therapy in the post-resuscitation period improves functional outcomes..

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Transition of intestinal fatty acid-binding protein on hypothermic circulatory arrest with cardiopulmonary bypass

Abstract Introduction: Intestinal fatty acid-binding protein (I-FABP) is increasingly employed as a highly specific marker of intestinal necrosis. However, the value of this marker associated with cardiovascular surgery with hypothermic..

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Hemiarch: The Real Operation for Ascending Aortic Aneurysm

Abstract The extent and technique of resection for ascending aortopathies remains debated. The 2 main camps are divided into those who believe in the hemiarch resection utilizing hypothermic circulatory arrest..

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Prolonged pulmonary support after cardiac surgery: incidence, risk factors and outcomes: a retrospective cohort study

Abstract Background Post–cardiac surgery pulmonary dysfunction may be underreported. Therefore, we evaluated associated risk factors for prolonged pulmonary support after cardiac surgery. Methods and materials We conducted a retrospective, observational..

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A Novel Anti-Pollution Filter for Volatile Agents During Cardiopulmonary Bypass: Preliminary Tests

Abstract Objective Concerns regarding pollution of the operating room by  and effects on atmospheric ozone depletion exist.  commonly are used during  to provide  independent of any supposed myocardial protective effects. The authors’ aim was..

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Protamine reduces whole blood platelet aggregation after cardiopulmonary bypass

Abstract Objectives: Platelet dysfunction is an important cause of postoperative bleeding after cardiac surgery. Protamine is routinely used for reversal of heparin after cardiopulmonary bypass (CBP), but may affect platelet..

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The Munich Lung Transplant Group: Intraoperative Extracorporeal Circulation in Lung Transplantation

Abstract Background This retrospective single-center study aimed to analyze transfusion requirements, coagulation parameters, and outcome parameters in patients undergoing lung transplantation (LuTx) with intraoperative extracorporeal circulatory support, comparing cardiopulmonary bypass..

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Concomitant atrial fibrillation surgery for people undergoing cardiac surgery

Abstract Background People with atrial fibrillation (AF) often undergo cardiac surgery for other underlying reasons and are frequently offered concomitant AF surgery to reduce the frequency of short‐ and long‐term..

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Outcome Comparison in Children Undergoing Extracorporeal Life Support Initiated at a Local Hospital by a Mobile Cardiorespiratory Assistance Unit or…

Abstract Purpose:  To compare characteristics and outcome in children undergoing extracorporeal life support initiated in an extracorporeal life support center or at the patient’s bedside in a local hospital, by..

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Potential identification of a claudicant group vulnerable to acute kidney injury

Abstract This observational study aimed to investigate the relationship between renal injury, endothelial function and oxidative stress in claudicants undergoing maximal treadmill exercise. Twenty patients with claudication were identified in..

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Effects of circuit albumin coating on coagulation and inflammatory response for patients receiving aortic arch replacement: a randomized controlled trial

Abstract Objective: To investigate whether human serum albumin coating before cardiopulmonary bypass (CPB) could improve platelet function and hemostasis and mitigate the inflammatory response among patients receiving aortic arch replacement..

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New mobile cardiac program extends reach of lifesaving treatment

While ECMO can work miracles, restoring life and health to patients whose hearts have ceased to function, the technology can only help if a patient can be connected to the..

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Dynamic Predictive Scores for Cardiac Surgery–Associated Acute Kidney Injury

Abstract Background Cardiac surgery–associated acute kidney injury (CSA‐AKI) is a common complication with a poor prognosis. In order to identify modifiable perioperative risk factors for AKI, which existing risk scores are..

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Effect of Oxygenator Size on Air Removal Characteristics: A Clinical Evaluation

Abstract During cardiopulmonary bypass (CPB), gaseous microemboli (GME) are released into the patients’ arterial bloodstream. Gaseous microemboli may contribute to the adverse outcome after cardiac surgery. Recently, two oxygenator models..

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Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients

Abstract BACKGROUND:  The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest..

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Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial

Abstract Purpose Postoperative cognitive dysfunction (POCD) occurs frequently after cardiac surgery. The pathophysiology of POCD remains elusive, but previous work showed that intravenous lidocaine may be protective against POCD, possibly..

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Efficacy of the RemoweLL cardiotomy reservoir for fat and leucocyte removal from shed mediastinal blood: a randomized controlled trial

Abstract Introduction: Re-transfusion of lipid particles and activated leucocytes with shed mediastinal blood (SMB) can aggravate cardiopulmonary bypass-associated inflammation and increase the embolic load. This study evaluated the fat and..

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Percutaneous mechanical circulatory support: current concepts and future directions

Abstract Introduction Percutaneous mechanical circulatory support (MCS) strategies have been in the clinical arena for approximately half a century, with the main aim of providing adequate systemic tissue perfusion, while..

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Extracorporeal Membrane Oxygenation for Pediatric Respiratory Failure: Risk Factors Associated With Center Volume and Mortality*

Abstract Objectives:  Recent analyses show higher mortality at low-volume centers providing extracorporeal membrane oxygenation. We sought to identify factors associated with center volume and mortality to explain survival differences and..

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Establishment of reference intervals and transfusion criterion for Sonoclot analysis

Abstract Sonoclot analyzer has been widely used in many countries. But the reference intervals provided by the manufacturer were derived from only 45 participants, and there was no cut-off value..

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A BMI >35 does not protect patients undergoing cardiac bypass surgery from red blood cell transfusion

Abstract The effect of obesity on allogeneic intraoperative blood product transfusion in patients undergoing coronary artery bypass graft surgery (CABG) is poorly understood. We analyzed the influence of obesity on..

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Preoperative hemostatic testing and the risk of postoperative bleeding in coronary artery bypass surgery patients

Abstract BACKGROUND We sought to assess predictability of excessive bleeding using thrombelastography (TEG), multiplate impedance aggregometry, and conventional coagulation tests including fibrinogen in patients undergoing coronary artery bypass graft (CABG)..

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Clinical equivalency of cardiopulmonary bypass and extracorporeal membrane oxygenation support for pediatric tracheal reconstruction

Abstract Objective Pediatric surgery for congenital tracheal stenosis continues to be a therapeutic challenge, and it often requires cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO) for intra-operative extracorporeal cardiorespiratory..

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Bivalirudin for Alternative Anticoagulation in Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract Background: Extracorporeal membrane oxygenation (ECMO) offers therapeutic options in refractory respiratory and/or cardiac failure. Systemic anticoagulation with heparin is routinely administered. However, in patients with heparin-induced thrombocytopenia or heparin..

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Single crossclamp: Safe training tool for coronary artery bypass grafting

Abstract Objective The single-crossclamp technique for coronary artery bypass grafting is recognized to reduce manipulation of the ascending aorta, and thereby improve neurological outcomes. However, there is a perceived disadvantage..

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Bleeding, transfusion and the risk of stroke after coronary surgery: A prospective cohort study of 2357 patients

Abstract Introduction This study was planned to investigate the impact of severe bleeding and  on the development of stroke after . Methods This  includes 2357 patients undergoing isolated CABG from the prospective European  (E-CABG)..

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Timing of adding blood to prime affects inflammatory response to neonatal cardiopulmonary bypass

Abstract Complications from systemic inflammation are reported in neonates following exposure to cardiopulmonary bypass. Although the use of asanguinous primes can reduce these complications, in neonates, this can result in..

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Beneficial effects of levosimendan on survival in patients undergoing extracorporeal membrane oxygenation after cardiovascular surgery

Abstract Background The impact of levosimendan treatment on clinical outcome in patients undergoing extracorporeal membrane oxygenation (ECMO) support after cardiovascular surgery is unknown. We hypothesized that the beneficial effects of..

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Short-term and longer-term survival after veno-arterial extracorporeal membrane oxygenation in an adult patient population: does older age matter?

Abstract Background: Veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) is increasingly being used for patients with refractory cardiopulmonary failure. This study evaluates the short-term (to discharge) and longer-term (1 year) survival..

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