Archives

Perfusfind S.L.

Abstract Over half a century ago, modelling and simulation of human cardiopulmonary physiology emerged as a research methodology, comparable to laboratory experiments and clinical studies. However, teaching fundamental physiological modelling..

Perfusfind S.L.

Abstract Background: Pediatric cardiac surgery requiring cardiopulmonary bypass (CPB) is associated with high transfusion rates. While transfusions increase risks of adverse events, existing evidence cannot differentiate whether risks arise from..

Perfusfind S.L.

Abstract Background Neurological complications are among the most serious adverse events in patients receiving extracorporeal membrane oxygenation (ECMO). Brain injury during ECMO is associated with increased mortality, long-term neurological deficits..

Perfusfind S.L.

Abstract Objectives To evaluate whether an activated clotting time (ACT)-guided, formula-based anticoagulation strategy supported by viscoelastic coagulation monitoring (ROTEM) improves perioperative coagulation management and reduces bleeding compared with standard weight-based..

Perfusfind S.L.

Abstract Objective To describe the application of a cell saver device (CSD) to manage blood loss in dogs and cats. Study design Retrospective study. Animals A total of 102 client-owned..

Perfusfind S.L.

Abstract Background Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) (VV-ECMO) and Veno-Artial Extracorporeal Membrane Oxygenation (VA-ECMO) have become evidence-based therapy options for patients with most severe heart and/or lung failure. Cannulas continue..

Perfusfind S.L.

Abstract Objectives: To describe the rate, characteristics, and outcomes of pediatric extracorporeal cardiopulmonary resuscitation (ECPR) for in-hospital cardiac arrest (IHCA) in Japan and evaluate temporal trends. Design: Retrospective cohort using..

Perfusfind S.L.

Abstract Operating room personnel are exposed to biological hazards such as needlestick injuries and blood and body fluid exposure, which pose risks of bloodborne infections. However, many of these incidents..

Perfusfind S.L.

Abstract Background Postcardiopulmonary bypass (CPB) bleeding is partly driven by impaired thrombin generation. Recent trials suggest differing clinical effects of fresh frozen plasma (FFP) and prothrombin complex concentrate (PCC), but..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) is an invaluable tool in cardiac surgery. In pediatric patients, it is almost exclusively deployed by congenital cardiac surgeons who are sufficiently trained. Pediatric ECMO..

Perfusfind S.L.

Abstract Support with veno-venous extracorporeal membrane oxygenation (VV-ECMO) can be considered for patients with severe (combined) hypoxemia and hypercapnia. By adjusting sweep gas flow (SGF), blood oxygenation and correction of..

Perfusfind S.L.

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is often combined with other temporary mechanical circulatory support (tMCS) in cardiogenic shock, yet combination-specific outcomes remain poorly defined. We compared temporal trends,..

Perfusfind S.L.

Abstract Donation following the confirmation of death based on circulatory criteria has proven to be a valuable strategy for increasing the availability of organs for transplantation. However, the standard super-rapid..

Perfusfind S.L.

Abstract Background: Myocardial ischemia–reperfusion during cardiac surgery is associated with complex metabolic alterations that reflect both myocardial injury and recovery. This prospective study aimed to characterize intraoperative lactate, pH, and..

Perfusfind S.L.

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) candidacy decisions are made under substantial uncertainty and are inconsistent. With a team including economist decision-scientists, we applied Regret Theory to hypothesize..

Perfusfind S.L.

Abstract Background Survivors of extracorporeal membrane oxygenation (ECMO) may experience persistent physical, cognitive, psychological, social, and quality-of-life impairments after intensive care unit (ICU) discharge. However, the core components of early..

Perfusfind S.L.

Abstract Objectives To compare clinical outcomes of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) combined with mechanical thrombectomy (MT) versus VA-ECMO alone in high-risk pulmonary embolism (PE). Design Systematic review and..

Perfusfind S.L.

Abstract Background/Objectives: Postoperative bleeding remains a major complication following coronary artery bypass grafting (CABG), contributing to transfusion requirements, reintervention, and morbidity. The objective of this study was to assess the..

Perfusfind S.L.

Abstract Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respiratory failure refractory to conventional measures. Its application has broadened across a wide spectrum..

Perfusfind S.L.

Abstract Objective To determine whether colloid choice within the cardiopulmonary bypass (CPB) priming strategy independently modifies the perioperative acid-base trajectory. Design Preplanned analysis of a single-center, double-blind, 3-arm randomized controlled..

Perfusfind S.L.

Abstract Plastics serve multiple functions in an industrialized society, including major applications in all aspects of healthcare such as single use syringes, coatings and implantable devices. Plastics break down into..

Perfusfind S.L.

Abstract Unmeasured anions are commonly detected in critically ill patients, yet their nature remains unclear. We examined whether endothelial glycocalyx degradation may be related to this unexplained anionic burden through..

Perfusfind S.L.

Abstract A 37-year-old patient (gravida 10, para 0–1–8-0) with class III obesity, obstructive sleep apnoea requiring continuous positive airway pressure and previous pulmonary emboli presented at 19 + 6 weeks' gestation with severe..

Perfusfind S.L.

Abstract Objectives To evaluate whether furosemide administration before cardiopulmonary bypass (CPB) is associated with altered intraoperative urinary oxygen tension (PuO₂) and early postoperative renal outcomes in patients undergoing elective on-pump..

Perfusfind S.L.

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an established therapy for severe respiratory failure; however, few studies have examined the validity of and prognostic factors for VV-ECMO implementation in..

Perfusfind S.L.

Abstract Increasingly, more neonatal respiratory extracorporeal membrane oxygenation (ECMO) patients in the Extracorporeal Life Support Organization (ELSO) registry have a primary diagnosis of Other. These patients, in addition to those..

Perfusfind S.L.

Abstract Objective: To evaluate the response of various oxygenation indices to the oxygen challenge test (OCT), prior to decannulation, in neonates supported with VA ECMO for respiratory indications, and to..

Perfusfind S.L.

Abstract Background Pulmonary complications occur frequently after cardiac surgery. Various intraoperative and perioperative mechanical ventilation strategies were investigated to reduce postoperative lung injury. Evidence of their benefits remains inconclusive. Methods..

Perfusfind S.L.

Abstract The application of cardiopulmonary bypass (CPB) has significantly advanced cardiovascular surgery. However, CPB-associated brain injury remains a critical complication that affects patient prognosis and quality of life. Overt stroke..

Perfusfind S.L.

Abstract The optimal timing for transitioning from noninvasive respiratory support to invasive mechanical ventilation and extracorporeal membrane oxygenation (ECMO) in severe acute respiratory distress syndrome (ARDS) remains controversial. PubMed and..