Archives

thumbnail
0 comment

Changes in Coagulation and Fibrinolysis Systems During the Perioperative Period of Acute Type A Aortic Dissection

Abstract Background: Acute type A aortic dissection (ATAAD) has a high risk of perioperative bleeding and often requires extensive blood product infusions. Analysis of the changes in coagulation and fibrinolysis..

Read More
thumbnail
0 comment

Establish a Nomogram of Cardiac Postoperative Cognitive Dysfunction

Abstract Objectives: Cardiac postoperative cognitive dysfunction (c-POCD) is a common complication. This article established a nomogram by analyzing preoperative and intraoperative data to help identify high-risk patients and take effective..

Read More
thumbnail
0 comment

Impact of CytoSorb on kinetics of vancomycin and bivalirudin in critically ill patients

Abstract CytoSorb is a promising tool to treat severe inflammatory status with multiple mechanisms in the acute care setting. Its effect on drugs is, however, poorly documented in vivo, although..

Read More
thumbnail
0 comment

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis

Abstract Objectives:  Several studies have reported prone positioning of nonintubated patients with coronavirus diseases 2019–related hypoxemic respiratory failure. This systematic review and meta-analysis evaluated the impact of prone positioning on..

Read More
thumbnail
0 comment

Impact of chronic kidney disease in 29 893 patients undergoing transcatheter or surgical aortic valve replacement from the German Aortic…

Abstract OBJECTIVES Chronic kidney disease (CKD) is a key risk factor in patients undergoing transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR). We analysed the impact of..

Read More
thumbnail
0 comment

The Right Ventricle in COVID-19 Lung Injury: Proposed Mechanisms, Management, and Research Gaps

Abstract CORONAVIRUS DISEASE 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is a complex multisystem disorder primarily characterized by pulmonary involvement.  Although lung injury leading to..

Read More
thumbnail
0 comment

Bedside angiography of distal perfusion catheter for veno-arterial extracorporeal membrane oxygenation

Abstract Background: The aim of this study was to evaluate the ipsilateral lower extremity (ILE) outcomes of patients who underwent bedside angiography via the distal perfusion catheter while on femoral..

Read More
thumbnail
0 comment

The heart of the ageing endurance athlete: the role of chronic coronary stress

Abstract Moderate physical exercise is associated with an irrefutable reduction in cardiac morbidity and mortality. The current guidelines recommend at least 150 min of moderate exercise or 75 min of..

Read More
thumbnail
0 comment

Axial flow ventricular assist devices in cardiogenic shock complicating acute myocardial infarction

Abstract Cardiogenic shock (CS) remains the leading cause of death in patients hospitalised with acute myocardial infarction with mortality as high as 40%–50% prior to hospital discharge. The failure of..

Read More
thumbnail
0 comment

Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy: A Word of Endorsement

Abstract Twenty years after the introduction of alcohol septal ablation (ASA) for the treatment of obstructive hypertrophic cardiomyopathy, the arrhythmogenicity of the ablation scar appears to be overemphasized. When systematically..

Read More
thumbnail
0 comment

Therapeutic Manipulation of Myocardial Metabolism: JACC State-of-the-Art Review

Abstract The mechanisms responsible for the positive and unexpected cardiovascular effects of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes remain to be defined...

Read More
thumbnail
0 comment

ST Segment Elevation in a Patient With Myocardial Metastases

Abstract A man in his 70s with a history of multiple prior ST-segment elevation myocardial infarctions (STEMIs) and squamous cell carcinoma of the lung with metastatic disease to the brain..

Read More
thumbnail
0 comment

Paediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic

Abstract The coronavirus disease 2019 (COVID-19) pandemic has impacted people of all ages. Although children have been largely spared from the direct impact of the pandemic and only a minority..

Read More
thumbnail
0 comment

How to help a weak heart

Abstract In this interview, the renowned cardiac surgeon Thierry Carrel explains what happens when the heart becomes weak, what the different treatment options are and why the new approach from..

Read More
thumbnail
0 comment

Superior Myocardial Protection Using “Polarizing” Adenosine, Lidocaine, and Mg2+ Cardioplegia in Humans

Abstract  with current methods of  is still incomplete , , . Several studies have shown that hyperkalemic solution may lead to cell injury , . Adenosine-lidocaine-magnesium (ALM) is a new normokalemic, “polarizing” method of cardioplegia that..

Read More
thumbnail
0 comment

Comparison of 4-Factor Prothrombin Complex Concentrate With Frozen Plasma for Management of Hemorrhage During and After Cardiac Surgery

Abstract Importance  Approximately 15% of patients undergoing cardiac surgery receive frozen plasma (FP) for bleeding. Four-factor prothrombin complex concentrates (PCCs) have logistical and safety advantages over FP and may be a..

Read More
thumbnail
0 comment

Minimally Invasive Versus Sternotomy for Mitral Surgery in the Elderly: A Systematic Review and Meta-Analysis

Abstract Objective The safety of minimally invasive mitral valve surgery (MIMVS) in elderly patients is still debated. Our objective was to perform a systematic review and meta-analysis of studies comparing..

Read More
thumbnail
0 comment

Extubate Before Venovenous Extracorporeal Membranous Oxygenation Decannulation or Decannulate While Remaining on the Ventilator? The EuroELSO 2019 Weaning Survey

Abstract Patients who receive venovenous extracorporeal membrane oxygenation (VV ECMO) support upon failure of invasive mechanical ventilation (IMV) and other adjuncts, including low tidal volume, prone positioning, adjusted positive end-expiratory pressure, and..

Read More
thumbnail
0 comment

We Asked the Experts: Autotransfusion for the Provision of Blood in Lower-and-Middle-Income Countries

Abstract Space travel is often touted as the pinnacle of human progress, with the current missions to Mars an example thereof []. For those living in Lower-and-Middle-Income Countries (LMICs), this..

Read More
thumbnail
0 comment

Basics of extra corporeal membrane oxygenation: a pediatric intensivist’s perspective

Abstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external..

Read More
thumbnail
0 comment

Testing for Coronary Microvascular Dysfunction

Abstract Coronary microvascular dysfunction refers to abnormal dilation and constriction of the small blood vessels in the heart.   What Is Coronary Microvascular Dysfunction? The small blood vessels in the heart,..

Read More
thumbnail
0 comment

Eosinophilic Myocarditis in a Patient with Sickle Cell Disease

Abstract A 23-year-old man with sickle cell disease treated with splenectomy and allogenic stem cell transplantation presented with recurrent chest pain, elevated cardiac enzymes, and unremarkable electrocardiography. His work-up revealed..

Read More
thumbnail
0 comment

The Safe Addition of Nitric Oxide into the Sweep Gas of the Extracorporeal Circuit during Cardiopulmonary Bypass and Extracorporeal Life…

Abstract Low cardiac output syndrome and the systemic inflammatory response are consequences of the cardiac surgical perioperative course. The mechanisms responsible are multifactorial, but recent studies have shown that nitric..

Read More
thumbnail
0 comment

Fetal circulation

The blood that flows through the fetus is actually more complicated than after the baby is born (). This is because the mother (the placenta) is doing the work that..

Read More
thumbnail
0 comment

Efficacy and cost-effectiveness of cell saver usage in the repair of thoracic aortic aneurysms and dissections

Abstract Introduction: A substantial amount of blood loss occurs during the open repair of aortic aneurysms or dissections. The aim of the present study is to determine the efficacy and..

Read More
thumbnail
0 comment

Timeout procedure in paediatric surgery: effective tool or lip service? A randomised prospective observational study

Abstract Background  For over a decade, the preoperative timeout procedure has been implemented in most paediatric surgery units. However, the impact of this intervention has not been systematically studied. This..

Read More
thumbnail
0 comment

Perioperative Cryoprecipitate Waste Reduction

Abstract Improvement of operating room efficiency regarding perioperative blood product transfusion is fundamental for surgical patients. The aim of this study was to 1) assess the use of cryoprecipitate in..

Read More
thumbnail
0 comment

Extracellular Vesicles in Autologous Cell Salvaged Blood in Orthopedic Surgery

  Abstract Background: Cell salvage is highly recommended in orthopedic surgery to avoid allogeneic transfusions. Preparational steps during cell salvage may induce extracellular vesicle (EV) formation with potential thrombogenic activity...

Read More
thumbnail
0 comment

Safety and Efficacy of Vasopressin After Fontan Completion: A Randomized Pilot Study

Take Home Points:    Vasopressin infusion after Fontan completion was associated with reduced transpulmonary gradient and chest tube drainage in the early postoperative period. A larger multi-institutional study will be..

Read More
thumbnail
0 comment

Acute kidney injury post‐heart transplant: An analysis of peri‐operative risk factors

Abstract Acute kidney injury is a common complication following heart transplantation, and the factors contributing to acute kidney injury are not well understood. We conducted a retrospective cohort study evaluating..

Read More