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Basics of extra corporeal membrane oxygenation: a pediatric intensivist’s perspective

Abstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external..

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Testing for Coronary Microvascular Dysfunction

Abstract Coronary microvascular dysfunction refers to abnormal dilation and constriction of the small blood vessels in the heart.   What Is Coronary Microvascular Dysfunction? The small blood vessels in the heart,..

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Eosinophilic Myocarditis in a Patient with Sickle Cell Disease

Abstract A 23-year-old man with sickle cell disease treated with splenectomy and allogenic stem cell transplantation presented with recurrent chest pain, elevated cardiac enzymes, and unremarkable electrocardiography. His work-up revealed..

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The Safe Addition of Nitric Oxide into the Sweep Gas of the Extracorporeal Circuit during Cardiopulmonary Bypass and Extracorporeal Life…

Abstract Low cardiac output syndrome and the systemic inflammatory response are consequences of the cardiac surgical perioperative course. The mechanisms responsible are multifactorial, but recent studies have shown that nitric..

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Fetal circulation

The blood that flows through the fetus is actually more complicated than after the baby is born (). This is because the mother (the placenta) is doing the work that..

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Efficacy and cost-effectiveness of cell saver usage in the repair of thoracic aortic aneurysms and dissections

Abstract Introduction: A substantial amount of blood loss occurs during the open repair of aortic aneurysms or dissections. The aim of the present study is to determine the efficacy and..

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Timeout procedure in paediatric surgery: effective tool or lip service? A randomised prospective observational study

Abstract Background  For over a decade, the preoperative timeout procedure has been implemented in most paediatric surgery units. However, the impact of this intervention has not been systematically studied. This..

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Perioperative Cryoprecipitate Waste Reduction

Abstract Improvement of operating room efficiency regarding perioperative blood product transfusion is fundamental for surgical patients. The aim of this study was to 1) assess the use of cryoprecipitate in..

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Extracellular Vesicles in Autologous Cell Salvaged Blood in Orthopedic Surgery

  Abstract Background: Cell salvage is highly recommended in orthopedic surgery to avoid allogeneic transfusions. Preparational steps during cell salvage may induce extracellular vesicle (EV) formation with potential thrombogenic activity...

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Safety and Efficacy of Vasopressin After Fontan Completion: A Randomized Pilot Study

Take Home Points:    Vasopressin infusion after Fontan completion was associated with reduced transpulmonary gradient and chest tube drainage in the early postoperative period. A larger multi-institutional study will be..

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Acute kidney injury post‐heart transplant: An analysis of peri‐operative risk factors

Abstract Acute kidney injury is a common complication following heart transplantation, and the factors contributing to acute kidney injury are not well understood. We conducted a retrospective cohort study evaluating..

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Hematologic evaluation of cardiopulmonary bypass circuits prepared with a novel block copolymer

Abstract Background. To decrease the complications associated with cardiopulmonary bypass, novel biomaterials have been introduced that may be less thrombogenic than standard synthetic surfaces.   Methods. Thirty-four patients undergoing coronary..

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mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease

Take Home Points: modified Dixon (mDixon) 3D cardiovascular magnetic resonance angiography (CMRA) demonstrates reduced artefact burden and better delineation of head and neck vessels as well as pulmonary veins compared..

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Une première pour le CHU : un cœur qui bat, hors de tout corps

  De battre le cœur a continué. Le 26 mars 2021, les équipes de chirurgie cardiaque et d’anesthésie-réanimation du CHU de Rennes ont réalisé une transplantation cardiaque d’un genre nouveau..

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A cardiopulmonary bypass strategy to support a patient with vein of Galen malformation

Abstract We present a dissection of the patent ductus arteriosus and pulmonary artery for surgical repair utilising cardiopulmonary bypass in the setting of vein of Galen malformation. Several strategies were..

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The Effect of Priming Solutions and Storage Time on Plasticizer Migration in Different PVC Tubing Types—Implications for Wet Storage of…

Abstract The wet priming of extracorporeal membrane oxygenation systems and storage of these systems for rapid deployment is common practice in many clinical centers. This storage policy is, however, seen..

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Long‐term renal function after venoarterial extracorporeal membrane oxygenation

Abstract Background The utilization of venoarterial extracorporeal membrane oxygenation (VA‐ECMO) as a life‐supporting therapy has increased exponentially over the last decade. As more patients receive and survive ECMO, there are..

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Volatile and Intravenous Anesthetics for Brain Protection in Cardiac Surgery: Does the Choice of Anesthesia Matter?

Abstract Postoperative neurologic complications have a significant effect on morbidity, mortality, and long-term disability in patients undergoing cardiac surgery. The etiology of brain injury in patients undergoing cardiac surgery is..

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Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID‐19

Abstract Both antiviral treatment with remdesivir and hemoadsorption using a CytoSorb® adsorption device are applied in the treatment of severe COVID‐19. The CytoSorb® adsorber consists of porous polymer beads that adsorb a..

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Hypercoagulopathy, acquired coagulation disorders and anticoagulation before, during and after extracorporeal membrane oxygenation in COVID-19: a case series.

Abstract Background: Thromboembolism and bleeding contribute to Coronavirus disease 2019 (COVID-19)’s morbidity and mortality and are also frequent complications of venovenous extracorporeal membrane oxygenation (vvECMO). As the interaction of the..

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Fraction of expired oxygen: an additional safety approach to monitor oxygen delivery to the heart lung machine oxygenator.

Abstract Background: Monitoring oxygen delivery to the oxygenator of a heart lung machine (HLM) is typically accomplished with an O2 analyzer connected to the gas inflow line. It is assumed when..

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Heparin-Free Lung Transplantation on Venovenous Extracorporeal Membrane Oxygenation Bridge.

Abstract Extracorporeal membrane oxygenation (ECMO) bridge to lung transplantation (LuTX) exposes the patients to a high risk of perioperative bleeding secondary to systemic anticoagulation and coagulation factors deficiency. With this..

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Cardiac surgery outcome during the COVID-19 pandemic: a retrospective review of the early experience in nine UK centres.

Abstract Background Early studies conclude patients with Covid-19 have a high risk of death, but no studies specifically explore cardiac surgery outcome. We investigate UK cardiac surgery outcomes during the..

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Modern practice and outcomes of reoperative cardiac surgery.

Abstract Objectives To evaluate recent practice and outcomes of reoperative cardiac surgery via re-sternotomy. Use of early versus late institution of cardiopulmonary bypass (CPB) before sternal re-entry was of particular..

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Different mechanisms of oxygenator failure and high plasma von Willebrand factor antigen influence success and survival of venovenous extracorporeal membrane…

Abstract Objective Failure of membrane oxygenator (MO) function of venovenous extracorporeal membrane oxygenators (VV ECMO) remains problematic. The development of device-induced coagulation disorder (COD) or worsened gas transfer (WGT) necessitates..

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Prognostic Utility of KDIGO Urine Output Criteria After Cardiac Surgery

Abstract Objectives Kidney Disease: Improving Global Outcomes (KDIGO) guidelines include assessment of creatinine and urine output to identify acute kidney injury (AKI). Whether urine output is an accurate indicator of..

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Neurological complications during veno-venous extracorporeal membrane oxygenation: Does the configuration matter? A retrospective analysis of the ELSO database

Abstract Background Single- (SL) and double-lumen (DL) catheters are used in clinical practice for veno-venous extracorporeal membrane oxygenation (V-V ECMO) therapy. However, information is lacking regarding the effects of the..

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Cerebrovascular autoregulation and arterial carbon dioxide in patients with acute respiratory distress syndrome: a prospective observational cohort study

Abstract Background Early hypercapnia is common in patients with acute respiratory distress syndrome (ARDS) and is associated with increased mortality. Fluctuations of carbon dioxide have been associated with adverse neurological..

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Determining Thresholds for Three Indices of Autoregulation to Identify the Lower Limit of Autoregulation During Cardiac Surgery

Abstract OBJECTIVES:  Monitoring cerebral autoregulation may help identify the lower limit of autoregulation in individual patients. Mean arterial blood pressure below lower limit of autoregulation appears to be a risk..

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Successful treatment of neonatal atrial flutter by synchronized cardioversion: case report and literature review

Abstract Background Atrial flutter (AFL) is a supraventricular tachyarrhythmia. In the ECG tracing, it is marked by a fast, irregular atrial activity of 280–500 beats per minute. AFL is known..

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