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Thoracotomy versus sternotomy? The effect of surgical approach on outcomes after left ventricular assist device implantation: A review of the…

Abstract Background and aim Thoracotomy approaches to left ventricular assist device (LVAD) implantation may reduce surgical morbidity and, through preservation of the pericardial restraint over the right heart, may reduce..

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Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following…

Abstract Background Acute kidney injury is a severe complication following cardiopulmonary bypass (CPB) and is associated with capillary leakage and microcirculatory perfusion disturbances. CPB-induced thrombin release results in capillary hyperpermeability..

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Essence of Cardiopulmonary Bypass Circuit and Intra-Aortic Balloon Pump

Abstract The modern day CPB circuit consists of a series of tubing, pumps, oxygenator, heat exchanger, and numerous safety and electrical components that allow for complete circulatory support, regulation of..

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Intraoperative Red Blood Cell Transfusion Decision-making

Abstract Objectives:  The objective of this work was to carry out a systematic review of clinical practice guidelines (CPGs) pertaining to intraoperative red blood cell (RBC) transfusions, in terms of..

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Neonatal respiratory and cardiac ECMO in Europe

Abstract Neonatal extracorporeal membrane oxygenation (ECMO) is a life-saving procedure for critically ill neonates suffering from a potentially reversible disease, causing severe cardiac and/or respiratory failure and refractory to maximal..

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Con: Routine Use of Fresh Frozen Plasma Should Not Be Used to Prime Cardiopulmonary Bypass Circuits During Cardiac Surgery

Abstract BLEEDING is a well-documented and frequently encountered complication after cardiac surgery, affecting roughly 2%-to-10% of all patients.  Major bleeding is a known risk factor for significant morbidity and mortality..

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The Use of Artificial Neural Networks to Determine In-Hospital Mortality After Coronary Artery Bypass Surgery

Abstract Objectives The aim of this study was to present an artificial neural network (ANN) model for the accurate estimation of in-hospital mortality and to demonstrate the validity of the..

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A contemporary review of paediatric heart transplantation and mechanical circulatory support

Abstract Improvements in the care of children with cardiomyopathy, CHDs, and acquired heart disease have led to an increased number of children surviving with advanced heart failure. In addition, the..

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Effect of lung recruitment maneuver on oxygenation, physiological parameters and mortality in acute respiratory distress syndrome patients: a systematic review…

Abstract Purpose: Among acute respiratory distress syndrome (ARDS) patients in intensive care units, the efficacy of lung recruitment maneuver (LRM) use is uncertain taking into account the most recent randomized..

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Impact of hepatic steatosis on outcomes after left ventricular assist device implantation

Abstract Background This single-center, retrospective study evaluates the impact of hepatic steatosis on outcomes after continuous-flow left ventricular assist device (LVAD) implantation. Methods Adults undergoing LVAD implantation between 2004 and..

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Modular minimally invasive extracorporeal circulation ensures perfusion safety and technical feasibility in cardiac surgery; a systematic review of the literature

Abstract Introduction: Despite extensive evidence that shows clinical of superiority of MiECC, worldwide penetration remains low due to concerns regarding air handling and volume management in the context of a..

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Cerebral Oximetry Monitoring in Patients Undergoing Surgery for Stanford Type A Aortic Dissection

Abstract Objectives The aim of this study was to evaluate the prognostic impact of cerebral regional oxygen saturation (crSO2) in patients undergoing surgery for Stanford type A aortic dissection (TAAD)...

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Evaluation of the impact of HMS Plus on postoperative blood loss compared with ACT Plus in cardiac surgery

Abstract BACKGROUND: The standardized management of anticoagulation during the cardiopulmonary bypass seems inaccurate because of patients and surgeries variability. This study evaluates if an individualized management of heparin and protamine..

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The Efficacy of Resin Hemoperfusion Cartridge on Inflammatory Responses during Adult Cardiopulmonary Bypass

Abstract Aim: This study aimed to evaluate the efficacy of the resin hemoperfusion device (HA380 hemoperfusion cartridge) on inflammatory responses during adult cardiopulmonary bypass (CPB).  Methods: Sixty patients undergoing surgical valve replacement..

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Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery

Abstract Objectives The objective of this study was to identify novel serum biomarkers specific to postoperative delirium after major cardiac surgery to provide insight into the pathologic processes involved in..

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CTCs detection from intraoperative salvaged blood in RCC–IVC thrombus patients by negative enrichment and iFISH identification: a preliminary study

Abstract Background Intra-operative cell salvage (IOCS) and leukocyte-depleted filter (LDF) are widely used and effective in saving blood. However, the safety issue concerning reinfusion of IOCS–LDF processed blood to renal..

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Novel autologous, high concentrated fibrin as advanced hemostatic agent for coronary surgery

Abstract Background Variability in transfusion outcomes and excessive postoperative bleeding represents a significant problem in cardiac surgery. The effort to reduce bleeding complications and transfusion outcomes is desirable. Our study..

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Subzero balance - simple modified ultrafiltration (SBUF-SMUF) technique for pediatric cardiopulmonary bypass

Abstract The use of cardiopulmonary bypass (CPB) can be associated with significant hemodilution, coagulopathy and a systemic inflammatory response for infants and children undergoing cardiac surgery. Intra-operative ultrafiltration has been..

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Comparison of Clinical Scoring Tools to Predict Heparin-Induced Thrombocytopenia in Cardiac Surgery

Abstract The 4Ts and HIT-Expert Probability (HEP) scoring tools for heparin-induced thrombocytopenia (HIT) have not been validated in cardiac surgery patients, and the reported sensitivity and specificity of the Post-Cardiopulmonary..

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Protocolized Whole-Body Computed Tomography Imaging After Extracorporeal Membrane Oxygenation (ECMO) Cannulation for Cardiac Arrest

Abstract Evaluate the utility of whole-body computed tomography (WBCT) imaging in detecting clinically significant findings in patients who have undergone extracorporeal membrane oxygenation (ECMO) cannulation for cardiac arrest (extracorporeal cardiopulmonary..

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Extracorporeal Life Support in Accidental Hypothermia with Cardiac Arrest—A Narrative Review

Abstract Severely hypothermic patients, especially suffering cardiac arrest, require highly specialized treatment. The most common problems affecting the recognition and treatment seem to be awareness, logistics, and proper planning. In..

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Pre-cannulation international normalized ratio is independently associated with mortality in veno-arterial extracorporeal membrane oxygenation

Abstract Objective  To explore whether pre-cannulation international normalized ratio (INR) is associated with in-hospital mortality in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) patients. Design Retrospective observational cohort study. Setting Quaternary care..

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Differential effects of prone position in COVID‑19‑related ARDS in low and high recruiters

Abstract Prone position quickly imposed as a cornerstone in the management of patients with acute respiratory distress syndrome (ARDS) induced by coronavirus disease 2019 (COVID-19) [1, 2]. The response to..

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Acute kidney injury in the critically ill: an updated review on pathophysiology and management

Abstract Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only affects acute morbidity and mortality, but also a patient’s long-term prognosis. In this narrative review,..

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Near-infrared spectroscopy device selection affects intervention management for cerebral desaturation during cardiopulmonary bypass surgery

Abstract Objective Currently, several near-infrared spectroscopy oximetry devices are used for detecting cerebral ischemia during cardiopulmonary bypass (CPB) surgery. We investigated whether two different models of near-infrared spectroscopy oximetry devices..

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Taskforce report on the diagnosis and clinical management of COVID‑19 associated pulmonary aspergillosis

Abstract Purpose: Invasive pulmonary aspergillosis (IPA) is increasingly reported in patients with severe coronavirus disease 2019 (COVID‑19) admitted to the intensive care unit (ICU). Diagnosis and management of COVID‑19 associated..

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Delirium in COVID‑19: can we make the unknowns knowns?

Abstract Delirium is an important public health problem. It is independently associated with worse clinical outcomes, including persistent cognitive impairment, increased mortality, and greater risk of institutionalization [1]. The prevalence..

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The Ethics of Extracorporeal Membrane Oxygenation: Revisiting the Principles of Clinical Bioethics

Abstract Background  has become accepted as a rescue therapy for cardiopulmonary shock, and there have been over 100,000  (ECMO) cases since 1987. Rapid growth has presented ethical challenges and concerns. Here, we discuss..

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Hyponatremia: An Overlooked Risk Factor Associated With Adverse Outcomes After Cardiac Surgery

Abstract Background  is an unrecognized risk factor for  after cardiac surgery. We sought to study the prevalence of preoperative hyponatremia and its impact on short-term and long-term outcomes after cardiac surgery...

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Critical care after the COVID‑19 outbreak in China: lessons and renaissance

Abstract Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, more than 153 million cases have been confirmed, and more than 3.20 million individuals have died worldwide. The strategies..

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