Abstract Background Recurrent observation of clot in the cardiopulmonary bypass circuit after the administration of a protamine test dose (PTD) prompted concern over the effects of PTDs on patient activated..
Read MoreAbstract Systemic hypertension (HTN) is a recognized complication of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in children. We sought to determine the prevalence and associated features of HTN in a..
Read MoreAbstract A prospective, observational single-center study was carried out. Pediatric patients undergoing congenital heart defect surgery were evaluated before, during, and after surgery. At each time point, sublingual microcirculation and..
Read MoreAbstract Introduction: Neurologic complications of open thoracic aortic surgery are devastating problems in patients with severely diseased aortas. This study aimed to clarify whether directing the aortic cannula tip toward..
Read MoreAbstract Objective Custodiol-HTK (Custodiol-HTK Koheler Chemie, GmbH, Bensheim, Germany) causes fluctuations in serum sodium levels, , and is associated with postoperative seizures. We investigated the influence of scavenging right atrial effluent during..
Read MoreAbstract Objective: The aim of this study was to evaluate outcome measures between our standard multidose cardioplegia protocol and a del Nido cardioplegia protocol in congenital heart surgery patients. Methods:..
Read MoreAbstract Objective after cardiac surgery can be difficult to assess, often requiring invasive measurements. Bioelectrical impedance vector analysis (BIVA) is based on patterns of resistance (R) and reactance (Xc), corrected..
Read MoreAbstract Introduction: Minimally invasive aortic valve replacement (MIAVR) requires changes in cannulation strategy and cardiopulmonary bypass (CPB) management when compared to the conventional approach (CAVR). We aimed at evaluating if..
Read MoreAbstract In vitro hemolysis testing is commonly used to determine hemocompatibility of ExtraCorporeal Membrane Oxygenation (ECMO). However, poor reproducibility remains a challenging problem, due to several unidentified influencing factors. The..
Read MoreAbstract A substantial part of COVID-19-patients suffers from multi-organ failure (MOF). We report on an 80-year old patient with pulmonary, renal, circulatory, and hepatic failure. We decided against the use..
Read MoreAbstract Hemoadsorption was used in a 59-year-old patient with an acute type A aortic dissection, who was on rivaroxaban and dual antiplatelet therapy with clopidogrel and acetylsalicylic acid. Our aim..
Read MoreAbstract Objectives: A new congenital heart surgery database (CKCV) with real-time online reporting function was recently developed in Turkey. All standard international parameters were used, but Aristotle Comprehensive Complexity score..
Read MoreAim The aim of this study was to compare (MI) and (MS) in terms of post-procedure health-related quality of life (HRQoL) and functional outcome. Method We conducted a multicentre prospective cohort study..
Read MoreAbstract Despite increasing improvement in extracorporeal membrane oxygenation (ECMO) technology and knowledge, thrombocytopenia and impaired platelet function are usual findings in ECMO patients and the underlying mechanisms are only partially..
Read MoreAbstract Study objective To describe and compare patient blood management (PBM) practices in cardiac surgery in nine European countries and identify the main risk factors for bleeding or transfusion according..
Read MoreAbstract Background: Extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest has improved mortality in post-cardiac surgery patients; however, loss of neurologic function remains one of the main and devastating complications...
Read MoreAbstract Objectives: The Japan Cardiovascular Surgery Database–Congenital section (JCVSD-Congenital) and the European Congenital Heart Surgeons Association (ECHSA) Congenital Heart Surgery Database (CHSD) share the same nomenclature. We aimed at comparing..
Read MoreAbstract Coagulation factor XII (fXII) is a plasma serine protease which belongs to the contact activation complex responsible for initiating the intrinsic coagulation pathway. fXII deficiency is a rare congenital..
Read MoreAbstract The role of extracorporeal membrane oxygenation (ECMO) in the management of severely ill patients with coronavirus disease 2019 (COVID-19) continues to evolve. The purpose of this study is to..
Read MoreAbstract Currently, lactate (Lac) is used to evaluate (MP) of hearts, donated after circulatory death (DCD). We hypothesize that monitoring of myocardial (mLDP) by Laser-Doppler-Perfusion is superior to Lac to evaluate perfusion..
Read MoreAbstract Extracorporeal membrane oxygenation is a life-saving intervention, but bleeding complications are frequent. Given that the combination of platelet loss and dysfunction is a major contributor to this acquired bleeding..
Read MoreAbstract Microcirculatory disturbances are commonplace after cardiopulmonary bypass. Postoperative atrial fibrillation (POAF) occurs in nearly 30% of patients undergoing conventional cardiac surgery. Landiolol, a short-acting i.v. beta blocker, could reduce..
Read MoreAbstract Patients with the coronavirus disease 2019 (COVID-19) sometimes develop refractory respiratory failure and may require venovenous extracorporeal membrane oxygenation (VV-ECMO). It is known that the severe acute respiratory syndrome..
Read MoreAbstract In this issue of BMJ Quality and Safety, Jorro-Barón and colleagues report the findings of a stepped-wedge cluster randomised trial (SW-CRT) to evaluate the implementation of the I-PASS handover system among..
Read MoreAbstract Introduction: The superiority of pulsatile perfusion during cardiopulmonary bypass remains controversial. We analyzed the frequency-domain characteristics and organ protection of pulsatile and nonpulsatile flow in adult patients with valvular..
Read MoreAbstract Objective: Mesenchymal stromal cells have important immunomodulatory and neuroprotective properties. The aim of this study was to evaluate the feasibility of mesenchymal stromal cell administration into a cardiopulmonary bypass..
Read MoreAbstract Systemic inflammatory responses in patients undergoing extracorporeal membrane oxygenation (ECMO) contribute significantly to ECMO-associated morbidity and mortality. In recent years, the number of type 2 diabetes mellitus patients has..
Read MoreAbstract Clotting, anticoagulation, platelet consumption, and poor platelet function are major factors in clinical extracorporeal circulation (ECC). We have shown that nitric oxide-releasing (NOReL) coatings prevent thrombosis in a rabbit..
Read MoreProne positioning (PP) has shown benefits in patients with refractory hypoxemia from acute respiratory distress syndrome (ARDS).1 The EOLIA trial demonstrated extracorporeal membrane oxygenation (ECMO) can be used for patients with..
Read MoreAbstract Background Cardiomyopathies in advanced stages and highly complex congenital heart disease may not be amenable to therapy or surgical correction thus being indicated pediatric heart transplant. In this study,..
Read More

















