Abstract Evaluate the utility of whole-body computed tomography (WBCT) imaging in detecting clinically significant findings in patients who have undergone extracorporeal membrane oxygenation (ECMO) cannulation for cardiac arrest (extracorporeal cardiopulmonary..
Read MoreAbstract Severely hypothermic patients, especially suffering cardiac arrest, require highly specialized treatment. The most common problems affecting the recognition and treatment seem to be awareness, logistics, and proper planning. In..
Read MoreAbstract Objective To explore whether pre-cannulation international normalized ratio (INR) is associated with in-hospital mortality in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) patients. Design Retrospective observational cohort study. Setting Quaternary care..
Read MoreAbstract Prone position quickly imposed as a cornerstone in the management of patients with acute respiratory distress syndrome (ARDS) induced by coronavirus disease 2019 (COVID-19) [1, 2]. The response to..
Read MoreAbstract Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only affects acute morbidity and mortality, but also a patient’s long-term prognosis. In this narrative review,..
Read MoreAbstract Objective Currently, several near-infrared spectroscopy oximetry devices are used for detecting cerebral ischemia during cardiopulmonary bypass (CPB) surgery. We investigated whether two different models of near-infrared spectroscopy oximetry devices..
Read MoreAbstract Purpose: Invasive pulmonary aspergillosis (IPA) is increasingly reported in patients with severe coronavirus disease 2019 (COVID‑19) admitted to the intensive care unit (ICU). Diagnosis and management of COVID‑19 associated..
Read MoreAbstract Delirium is an important public health problem. It is independently associated with worse clinical outcomes, including persistent cognitive impairment, increased mortality, and greater risk of institutionalization [1]. The prevalence..
Read MoreAbstract Background has become accepted as a rescue therapy for cardiopulmonary shock, and there have been over 100,000 (ECMO) cases since 1987. Rapid growth has presented ethical challenges and concerns. Here, we discuss..
Read MoreAbstract Background is an unrecognized risk factor for after cardiac surgery. We sought to study the prevalence of preoperative hyponatremia and its impact on short-term and long-term outcomes after cardiac surgery...
Read MoreAbstract Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, more than 153 million cases have been confirmed, and more than 3.20 million individuals have died worldwide. The strategies..
Read MoreAbstract Objective: Exposure to cerebral emboli is ubiquitous and may be harmful in cardiac surgery utilizing cardiopulmonary bypass. This was a prospective observational study aiming to compare emboli exposure in..
Read MoreAbstract Objective: To study the correlation between the mean arterial pressure (MAP) level in the first 6 hours of extracorporeal cardiopulmonary resuscitation (ECPR) and patients’ neurological outcomes. Methods: Sex, age, basic..
Read MoreAbstract Purpose: Extracorporeal membrane oxygenation (ECMO) use for severe coronavirus disease 2019 (COVID‑19) patients has increased during the course of the pandemic. As uncertainty existed regarding patient’s outcomes, early guidelines..
Read MoreAbstract Introduction Multiple studies have shown a decrease in the inflammatory response with minimized bypass circuits leading to less complications and mortality rate. On the other hand, some other studies..
Read MoreAbstract Background Aortic arch repair for aortic dissection is still associated with a high mortality rate. Providing adequate means of neuromonitoring to guide cerebral hemodynamics is advantageous, especially during selective anterior..
Read MoreAbstract Postcardiotomy shock (PCS) has historically been associated with substantial morbidity and mortality. Mortality at discharge is reportedly more than 60%. We investigated the outcomes of our standardized approach to..
Read MoreAbstract Background: Cardiac surgery with extracorporeal circulation (ECC) requires the administration of anticoagulant drugs to maintain ACT ranges 400–600 seconds, which requires exhaustive coagulation monitoring for which various point-of-care devices..
Read MoreAbstract Background The dose of protamine required following cardiopulmonary bypass (CPB) is often determined by the dose of heparin required pre-CPB, expressed as a fixed ratio. Dosing based on mathematical..
Read MoreAbstract Objectives after cardiac surgery remains of uncertain clinical significance. Therefore, we investigated the relationship of severity across urine output and creatinine domains with the risk for major adverse kidney events..
Read MoreAbstract Cardioplegic solutions are used in cardiac surgery to achieve controlled cardiac arrest during operations, making surgery safer. Cardioplegia can either be blood or crystalloid based, with perceived pros and..
Read MoreCyclosporine A-enhanced cardioplegia preserves mitochondrial basal respiration after ischemic arrest
Abstract Background: Mitochondrial permeability transition pore (mPTP) opening plays a crucial role in cell death during ischemia-reperfusion injury (IRI). Cyclosporine A (CsA) inhibits mPTP opening. This study aimed to investigate..
Read MoreAbstract Venovenous extracorporeal membrane oxygenation (VV-ECMO) has been used as a rescue therapy for patients with refractory coronavirus disease (COVID-19)–associated severe acute respiratory distress syndrome (ARDS) with survival rates similar..
Read MoreAbstract We report a successful pediatric bridge to transplant following application of the ProTekDuo Cannula to provide right ventricular support in a 12-year-old child with biventricular cardiomyopathy and on left..
Read MoreAbstract In patients with Fontan palliation, the systemic and pulmonary circulation is in series and supported by a single ventricle, resulting in fragile hemodynamics. Cardiac output is driven by low..
Read MoreAbstract The vast majority of children with congenital heart disease (CHD) in high-income countries survive into adulthood. Further, paediatric cardiac services have expanded in middle-income countries. Both evolutions have resulted..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has been used with increasing frequency to support patients with acute respiratory failure, most commonly, and severe forms of acute respiratory distress syndrome (ARDS). The..
Read MoreAbstract In SARS-CoV-2 patients with severe acute respiratory distress syndrome (ARDS), Veno-Venous Extracorporeal Membrane Oxygenation (V-V ECMO) was shown to provide valuable treatment with reasonable survival in large multi-centre investigations...
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