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Fluid resuscitation after cardiac surgery in the intensive care unit: A bi-national survey of clinician practice. (The FRACS-ICU clinician survey)

Abstract Context and Aims: To describe current fluid and vasopressor practices after cardiac surgery in Australia and New Zealand cardiothoracic intensive care units (ICU).  Design and Setting: This web-based survey was conducted..

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Renal function and inflammatory response in neonates undergoing cardiac surgery with or without antegrade cerebral perfusion—a post hoc analysis

Abstract Background: Cardiopulmonary bypass (CPB) may lead to tissue hypoxia, inflammatory response, and risk for acute kidney injury (AKI). We evaluated the prevalence of AKI and inflammatory response in neonates undergoing..

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Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation

Abstract Introduction: Many donor organs contain significant leukocyte reservoirs which upon transplantation activate recipient leukocytes to initiate acute rejection. We aimed to assess whether non-ischemic heart preservation via ex vivo perfusion promotes immunodepletion..

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Effect of Cardiac Surgery on One-Year Patient-Reported Outcomes: A Prospective Cohort Study

Abstract Background Current cardiac surgery risk algorithms and quality measures focus on perioperative outcomes. However, delivering high-value, patient-centered cardiac care will require a better understanding of long-term patient-reported quality of..

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Direct Versus Side Graft Cannulation From the Right Axillary Artery in Thoracic Aortic Surgery

Abstract Background The  can be cannulated for antegrade  directly or by employing a prosthetic  anastomosed to the artery. Methods From 2008 until 2019, 688 patients underwent axillary artery . Of those, 287 underwent direct..

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Perioperative Coronavirus Vaccination—Timing and Implications: A Guidance Document

Abstract Executive Summary  surgical patients are at risk of increased  disease severity. Several important factors influence the administration of the coronavirus disease vaccine in the . This guidance statement outlines current information..

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Education of Children With Cyanotic Congenital Heart Disease After Neonatal Cardiac Surgery

Abstract Background The aim of the study was to evaluate the educational achievement of patients diagnosed with  physiology (UVHP) or transposition of the  (TGA) after neonatal cardiac surgery. Methods An exploratory online..

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Human factors in ECLS – A keystone for safety and quality – A narrative review for ECLS providers

Abstract Introduction Although the technology used for extracorporeal life support (ECLS) has improved greatly in recent years, the application of these devices to the patient is quite complex and requires..

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Impact of Corticosteroids on Cardiopulmonary Bypass Induced Inflammation in Children: A Meta-Analysis

Abstract Background Corticosteroids suppress the inflammatory response to  in children undergoing cardiac surgery. What is less clear is the impact of corticosteroids on the postoperative course. Methods A systematic review and..

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Miniaturized Fontan Circulation Assist Device: Chronic In Vivo Evaluation

Abstract We have miniaturized and optimized our implantable rotary blood pump developed to provide long-term mechanical right heart support for patients who have failing Fontan circulation. The objective of this..

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Antithrombin Dose Optimization in Extracorporeal Membrane Oxygenation in Infants

Abstract Anticoagulation in extracorporeal membrane oxygenation (ECMO) is challenging, with significant morbidity and mortality associated with thrombotic complications. Unfractionated heparin (UFH) is commonly used, which depends on native antithrombin (AT)..

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Comparison of ECMO vs ECpella in patients with non post-pericardiotomy cardiogenic shock: An updated meta-analysis

Abstract Introduction The impact of Impella and ECMO (ECPELLA) in  (CS) remains to be defined. The aim of this meta-analysis is to evaluate the benefit of ECPELLA compared to VA-ECMO in..

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IMPACT OF PULSE PRESSURE ON CLINICAL OUTCOME IN EXTRACORPOREAL CARDIOPULMONARY RESUSCITATION PATIENTS

Abstract The researchers realized that more than half a million people in America suffer cardiac arrest each year. In Europe, more that quarter a million people suffer out of hospital..

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Cardiac injury in COVID-19

Abstract Patients with coronavirus disease 2019 (COVID-19) can present with a large panel of cardiac manifestations, including myocardial infarction with (type 1) or without (type 2) obstructive coronary artery disease,..

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Low Mean Arterial Pressure During Cardiopulmonary Bypass and the Risk of Acute Kidney Injury: A Propensity Score Matched Observational Study

Abstract Introduction Low mean arterial pressure (MAP) periods occur frequently during cardiopulmonary bypass (CPB), and their management remains controversial. Our aim was to correlate MAP during CPB with the occurrence..

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The Role of Multimodality Imaging in Athlete’s Heart Diagnosis: Current Status and Future Directions

Abstract “Athlete’s heart” is a spectrum of morphological and functional changes which occur in the heart of people who practice physical activity. When athlete’s heart occurs with its most marked..

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Postoperative Hematocrit and Adverse Outcomes in Pediatric Cardiac Surgery Patients: A Cross-Sectional Study From the Society of Thoracic Surgeons and…

Abstract BACKGROUND:  We sought to examine potential associations between pediatric postcardiac surgical hematocrit values and postoperative complications or mortality. METHODS:  A retrospective, cross-sectional study from the Society of Thoracic Surgeons..

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Preoperative Anemia and Risk for Perioperative Neurocognitive Dysfunction in Cardiac Surgery Patients: A Retrospective Analysis

Abstract Objectives To evaluate whether there is a relationship between preoperative anemia and domain-specific cognitive performance in patients undergoing cardiac surgery. Design Retrospective analysis of data collected from a randomized..

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Improvement of predicted hematocrit values after the initiation of cardiopulmonary bypass in cardiovascular surgery

Abstract Hematocrit (Hct) values after the initiation of cardiopulmonary bypass (CPB) must be maintained appropriately to avoid perioperative complications. Therefore, an accurate prediction is required. However, the standard prediction equation..

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Modified ultrafiltration reduces postoperative blood loss and transfusions in adult cardiac surgery: a meta-analysis of randomized controlled trials

Abstract   OBJECTIVES Cardiopulmonary bypass in cardiac surgery has been associated with several deleterious effects including haemodilution and systemic inflammation. Modified ultrafiltration (MUF) has been well established in paediatric cardiac..

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Outcomes of Pediatric Patients With Sepsis Related to Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus Infections Requiring Extracorporeal Life Support: An…

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is increasingly utilized for pediatric sepsis unresponsive to steroids and inotropic support. Outcomes of children with sepsis are influenced by the type of pathogen causing..

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Epinephrine administration in venoarterial extracorporeal membrane oxygenation patients is associated with mortality: a retrospective cohort study

Abstract Aims Knowledge about the impact of epinephrine on the outcome in venoarterial (VA) extracorporeal membrane oxygenation (ECMO) patients is limited, and existing data are conflicting. Methods and results We..

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Comparison of Bivalirudin Versus Unfractionated Heparin for Anticoagulation in Adult Patients on Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) contributes to coagulopathy, necessitating systemic anticoagulation to prevent thrombosis. Traditionally, unfractionated heparin (UFH) has been the anticoagulant of choice, however, due to many inadequacies new evidence suggests..

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Retrograde autologous priming method reduces plasma free hemoglobin level in aortic surgery

Abstract Background:  Although conventional cardiopulmonary bypass (cCPB) is still the most widely used method in open heart surgery, methods such as retrograde autologous priming (RAP) are increasingly popular in terms..

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Association Between Exogenous Nitric Oxide Given During Cardiopulmonary Bypass and the Incidence of Postoperative Kidney Injury in Children.

Abstract Objective To compare the incidence and severity of acute kidney injury following open heart surgery with cardiopulmonary bypass in children after administration of exogenous nitric oxide. Design Retrospective cohort..

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Les soldats du cœur - Ecmo Paris

Abstract Une unité spéciale de médecins pratique des opérations cardiaques au plus près des malades, sur les trottoirs de… Paris ! De la médecine "de guerre" en temps de paix. Un..

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A pumpless artificial lung without systemic anticoagulation: The Nitric Oxide Surface Anticoagulation system

Abstract Background Artificial lungs have the potential to serve as a bridge to transplantation or recovery for children with end-stage lung disease dependent on extracorporeal life support, but such devices..

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A Uniform and Robust Bioinspired Zwitterion Coating for Use in Blood-Contacting Catheters with Improved Anti-Inflammatory and Antithrombotic Properties

Abstract Inflammation and thrombosis are two major complications of blood-contacting catheters that are used as extracorporeal circuits for hemodialysis and life-support systems. In clinical applications, complications can lead to increased..

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Use of laboratory testing for prediction of postoperative bleeding volume in cardiovascular surgery

Abstract Background Coagulopathy and following massive bleeding are complications of cardiovascular surgery, particularly occurring after procedures requiring prolonged cardiopulmonary bypass (CPB). Reliable and rapid tests for coagulopathy are desirable for..

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