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Impaired Blood Flow? Tension Pneumothorax on Extracorporeal Support

Abstract A 55-year-old patient experiencing severe coronavirus disease 19 (COVID-19) related acute refractory respiratory failure requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) support, with femoro-femoral approach, suddenly developed both signs of..

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Persistent Hypoxemia in COVID-19 Patients on ECMO: Keep Your Eyes on the Prize

Abstract Venovenous extracorporeal membrane oxygenation (VV-ECMO) has been used during the COVID-19 pandemic to support patients with the most severe cases of COVID-19 acute respiratory distress syndrome (ARDS). The earliest..

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Myocardial Protection With Different Cardioplegia in Adult Cardiac Surgery: A Network Meta-Analysis

Abstract Aim Cardioplegia is one of the most studied fields of myocardial protection during cardiac surgery. However, the most effective cardioplegia for protection in adult cardiac surgery remains unknown. Method PubMed and other..

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Our 10-Point ECMO Checklist

How do you know when it’s time to take your ECMO program to the next level? Though COVID-19 cases may be dropping for the time being, the need for ECMO..

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Temporary mechanical circulatory support for COVID-19 patients: A systematic review of literature

Abstract Objective Myocardial damage occurs in up to 25% of coronavirus disease 2019 (COVID-19) cases. While veno-venous extracorporeal life support (V-V ECLS) is used as respiratory support, mechanical circulatory support..

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Cardiac Surgery and Blood-Saving Techniques: An Update

Abstract Cardiac surgery is typically attributed with a significant risk of intraoperative blood loss and allogeneic blood transfusions. Intraoperative blood loss, allogenic blood transfusions, high dose anticoagulation requirement, and interactions..

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Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study

Abstract Objective To estimate the effect of extracorporeal membrane oxygenation (ECMO) compared with conventional mechanical ventilation on outcomes of patients with covid-19 associated respiratory failure. Design Observational study. Setting 30 countries across five..

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Development of Survey Scales for Measuring Exposure and Behavioral Responses to Disruptive Intraoperative Behavior

Abstract Objectives  Disruptive intraoperative behavior has detrimental effects to clinicians, institutions, and patients. How clinicians respond to this behavior can either exacerbate or attenuate its effects. Previous investigations of disruptive..

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Intraoperative Hypotension and Acute Kidney Injury, Stroke, and Mortality during and outside Cardiopulmonary Bypass: A Retrospective Observational Cohort Study

Abstract Background In cardiac surgery, the association between hypotension during specific intraoperative phases or vasopressor-inotropes with adverse outcomes remains unclear. This study’s hypothesis was that intraoperative hypotension duration throughout the..

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Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial

Abstract Background: Cardiac surgery often represents the only treatment option in patients with infective endocarditis (IE). However, IE surgery may lead to a sudden release of inflammatory mediators, which is..

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Risk Factors for Acute Kidney Injury Following Cardiac Surgery and Performance of Leicester Score in a Spanish Cohort

Abstract The incidence of acute kidney injury following cardiac surgery (CSA-AKI) is up to 30%, and it places patients at an increased risk of death. The Leicester score (LS) is..

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Prothrombin Complex Concentrates to Treat Coagulation Disturbances: An Overview With a Focus on Use in Infants and Children

Abstract Various factors may lead to coagulation disturbances following cardiopulmonary bypass and surgery for congenital heart disease. In addition to the risks associated with the administration of allogeneic blood products,..

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Predictors of Survival and Favorable Neurologic Outcome in Patients Treated with eCPR: a Systematic Review and Meta-analysis

Abstract Extracorporeal cardiopulmonary resuscitation (eCPR) can improve survival in selected patients with cardiac arrest (CA). In this meta-analysis, we evaluated factors associated with short-term survival and favorable neurologic outcome (FNO)..

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Cerebrum and Cardiac Protection with Allopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL):…

Abstract Background Neonates with critical congenital heart disease (CCHD) undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at risk of brain injury that may result in adverse neurodevelopment. To date,..

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Early Use of Methylene Blue in Vasoplegic Syndrome: A 10-Year Propensity Score-Matched Cohort Study

Abstract Background: Vasoplegic syndrome is associated with increased morbidity and mortality in patients undergoing cardiac surgery. This retrospective, single-center study aimed to evaluate the effect of early use of methylene..

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Initial experience with minimally invasive extracorporeal circulation in coronary artery bypass graft reoperations

Abstract AIMS OF THE STUDY: Minimally invasive extracorporeal circulation (MiECC) is an established alternative to conventional extracorporeal circulation (CECC) in coronary artery bypass graft surgery (CABG), but data on its use in cardiac reoperations..

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Impact of the inspiratory oxygen fraction on the cardiac output during jugulo-femoral venoarterial extracorporeal membrane oxygenation in the rat

Abstract Background Venoarterial extracorporeal membrane oxygenation (V-A ECMO) with femoral access has gained wide acceptance in the treatment of critically ill patients. Since the patient´s cardiac output (CO) can compete..

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Stone heart syndrome after prolonged cardioplegia induced cardiac arrest in open-heart surgery – a pilot study on pigs

Abstract OBJECTIVES : To investigate Stone Heart Syndrome (SHS) as consequence of prolonged ischemic arrest in an experimental study on pigs in regards to onset of SHS and pathological changes...

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Waitlist Outcomes for Children With Congenital Heart Disease: Lessons Learned From Over 5000 Heart Transplant Listings in the United States

Abstract Background We evaluated the impact of pediatric heart-allocation policy changes over time and the approval of the Berlin ventricular assist device (VAD) on waitlist (WL) outcomes for children with..

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Management of Circuit Air in Extracorporeal Membrane Oxygenation: A Single Center Experience

Abstract Air in circuit in patients receiving extracorporeal membrane oxygenation (ECMO) is an emergency. Different protocols have been suggested to deal with this rare but fatal complication, but their efficacies..

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Veno-Venous Extracorporeal Rewarming Using Dual-Lumen Cannula in Accidental Hypothermia

Abstract Accidental hypothermia with a core temperature below 28°C is associated with an increased risk of hemodynamic instability. It is difficult to predict which patients will survive with a favorable..

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Routine Neuroimaging: Understanding Brain Injury in Pediatric Extracorporeal Membrane Oxygenation*

Abstract OBJECTIVES:  This project aims to describe brain injuries on routine neuroimaging in a large single-center neonatal and pediatric cohort supported by extracorporeal membrane oxygenation. The study also aims to..

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Discrete responses of erythrocytes, platelets, and von Willebrand factor to shear

Abstract Despite decades of technological advancements in blood-contacting medical devices, complications related to shear flow-induced blood trauma are still frequently observed in clinic. Blood trauma includes , , and degradation of High..

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A Theoretical Model of Flow Disruptions for the Anesthesia Team During Cardiovascular Surgery

Abstract Objectives  This investigation explores flow disruptions observed during cardiothoracic surgery and how they serve to disconnect anesthesia providers from their primary task. We can improve our understanding of this..

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Extracorporeal Membrane Oxygenation Cannulae-related Infection: Diagnostic Difficulties and Potential Prevention

Abstract We read with interest the recently-published article by Winiszewski et al. detailing the prevalence and risk factors associated with extracorporeal membrane oxygenation (ECMO) cannulae-related infections (CRIs). Winiszewski highlights a number of..

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Is bivalirudin an alternative anticoagulant for extracorporeal membrane oxygenation (ECMO) patients? A systematic review and meta-analysis

Abstract Background Anticoagulation is important for extracorporeal membrane oxygenation (ECMO). Heparin is widely used; however, in some cases, it is not suitable for patients. Bivalirudin has been recently proposed for..

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Using machine learning to predict perfusionists’ critical decision-making during cardiac surgery

Abstract The cardiac surgery operating room is a high-risk and complex environment in which multiple experts work as a team to provide safe and excellent care to patients. During the..

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Efficacy of Del Nido Cardioplegia in Adult Cardiac Procedures with Prolonged Aortic Cross Clamp Time

Abstract Purpose Equivalent myocardial protection and clinical outcomes have been demonstrated with the use of del Nido (DC) when compared to blood cardioplegia (BC) in adult isolated CABG and valve..

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PATHOBIOLOGY OF MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY

Abstract This review presents an integrated approach to the analysis of myocardial ischemia and reperfusion injury and the modulating influence of myocardial conditioning during the evolution of acute myocardial infarction..

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