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Temporary mechanical circulatory support devices: practical considerations for all stakeholders

Abstract Originally intended for life-saving salvage therapy, the use of temporary mechanical circulatory support (MCS) devices has become increasingly widespread in a variety of clinical settings in the contemporary era...

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Ventricular morphology of single ventricle hearts has a significant impact on outcomes after Fontan palliation. A meta-analysis

Abstract Objectives A conclusive interpretation of the role of ventricular dominance in outcomes after Fontan palliation has not been formulated yet. We conducted a systematic review and meta-analysis of scientific..

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Continuous-Flow Ventricular Assist Device Support in Adult Congenital Heart Disease: A 15-Year, Multicenter Experience of Temporary and Durable Support

Abstract Heart failure (HF) is common in adult congenital heart disease (ACHD) patients; however, use of continuous-flow ventricular assist devices (CF-VADs) remains rare. We reviewed outcomes of patients with congenital heart..

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Timing of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

Abstract Objectives:  To assess the association of timing to prone positioning (PP) during venovenous extracorporeal membrane oxygenation (V-V ECMO) with the probability of being discharged alive from the ICU at..

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Sequestration of Antimicrobial Agents in Xcoating and Heparin-Coated Extracorporeal Membrane Oxygenation Circuits: An In Vitro Study

Abstract Limited data exist to guide antimicrobial therapy commonly prescribed to patients undergoing extracorporeal membrane oxygenation (ECMO). This study aimed to describe the kinetics of the cefazolin, doripenem, daptomycin, and levofloxacin in..

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Controversies in extracorporeal membrane oxygenation: Immediate versus watchful waiting for venoarterial extracorporeal membrane oxygenation venting

Abstract In patients in cardiogenic shock (CS), mechanical circulatory support (MCS) may improve systemic perfusion without increasing myocardial work. Restoration of oxygen delivery with reduced myocardial oxygen demand favors myocardial..

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Unloading the left ventricle in venoarterial extracorporeal life support: The urgent need of speaking the same language!

Abstract We have read the review article entitled “Controversies in ECMO: Immediate versus Watchful Waiting for VA-ECMO Venting” by Cavayas and colleagues, published in the Special Issue of Invited Presentations:..

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CytoSorb haemoadsorption for removal of apixaban—A proof-of-concept pilot case for a randomized controlled trial

Abstract What is known and objective Emergent cardiac surgery in patients under anticoagulant therapy is still a major point of concern. Recently approved reversal agents are often not available or..

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The Effects of Targeted Changes in Systemic Blood Flow and Mean Arterial Pressure on Urine Oximetry During Cardiopulmonary Bypass

Abstract Objectives Poor medullary oxygenation is implicated in the evolution of acute kidney injury. The authors sought to determine if increasing systemic flow and mean arterial pressure could improve urine..

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‘You can’t do quality between surgical cases and tea time’: barriers to surgeon engagement in quality improvement

Abstract Much has been written about the challenges of surgeon engagement in quality and safety improvement work. In Taitz and colleagues’ 2011 seminal work, one interviewee alluded to the difficulties..

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A nomogram to predict nosocomial infection in patients on venoarterial extracorporeal membrane oxygenation after cardiac surgery

Abstract Introduction After cardiac surgery, patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) have a higher risk of nosocomial infection in the intensive care unit (ICU). We aimed to establish an..

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Retrograde cerebral perfusion for intracardiac air embolism in Fontan procedure

Abstract We report the case of a 5-year-old boy who suffered from an intracardiac air influx with suspected cerebral air embolism during the Fontan procedure. We immediately transformed the cardiopulmonary..

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Right axillary artery cannulation in acute type A aortic dissection with involvement of the right axillary artery

Abstract Objective Right axillary artery is currently recommended for arterial cannulation in surgery for acute type A aortic dissection. However, the feasibility of cannulation on a dissected right axillary artery..

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SynCardia Temporary Total Artificial Heart: Single-Center Experience at a Children’s Hospital

Abstract The SynCardia temporary total artificial heart (TAH-t) is a pneumatically driven pulsatile device that replaces a patient’s ventricles and all four valves. It is now available in two sizes..

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Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: Results of the ECMO-CS Randomized Clinical Trial

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly being used for circulatory support in cardiogenic shock patients, although the evidence supporting its use in this context remains insufficient. The aim..

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Vasoplegia is Predicted by Preoperative Platelet-Leucocyte conglomerate Indices in Cardiac Surgery (VASOPLEGICS): A retrospective single-center study

Abstract Background: Post-cardiotomy vasoplegia syndrome (VS) is often linked to an exaggerated inflammatory response to cardiopulmonary bypass (CPB). At the same time, the prognostic role of platelet-leucocyte indices (PLIs) and leucocyte..

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Vasoplegic Syndrome after Cardiopulmonary Bypass in Cardiovascular Surgery: Pathophysiology and Management in Critical Care

Abstract Vasoplegic syndrome (VS) is a common complication following cardiovascular surgery with cardiopulmonary bypass (CPB), and its incidence varies from 5 to 44%. It is defined as a distributive form..

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Effect of Hypoxemia on Outcome in Respiratory Failure Supported With Extracorporeal Membrane Oxygenation: A Cardinality Matched Cohort Study

Abstract Venovenous extracorporeal membrane oxygenation (ECMO) is recommended in adult patients with refractory acute respiratory failure (ARF), but there is limited evidence for its use in patients with less severe..

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Associations of cephalad drainage in neonatal veno-venous ECMO – A mixed-effects, propensity score adjusted retrospective analysis of 20 years of…

Abstract Background Neurologic complications can occur during neonatal Veno-Venous (VV) ECMO. The addition of a cephalad drainage cannula (i.e., VVDL+V) to dual lumen cannulation (i.e., VVDL) has been advocated to..

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Cor triatriatum sinister: Long-term surgical outcomes in children and a proposal for a new classification

Abstract Background: Cor Triatriatum Sinister (CTS) is a rare congenital anomaly with an estimated incidence of 0.4%, resulting from abnormal left atrial septation. It may present in isolation or in association..

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Hemostatic alterations during extracorporeal membrane oxygenation in ovine veno-venous and veno-arterial models

Abstract Background Extracorporeal membrane oxygenation (ECMO) has salvaged many people's life during global pandemics. However, ECMO is associated with a high incidence of hemostatic complications. This study aims to explore..

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Considerations for Reoperative Heart Valve Surgery

Abstract Reoperative valve surgery is being performed with increasing frequency in the last decades. This is mainly due to the increasing use of bioprosthetic valves, a growing population of patients..

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'Enhanced Lung Rest' with CytoSorb and ECMO Achieves High Survival in 100 Critically Ill COVID-19 Patients with Refractory Lung Failure…

Abstract PRINCETON, N.J., Nov. 2, 2022 /PRNewswire/ -- CytoSorbents Corporation (NASDAQ: ), a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery using its CytoSorb® blood purification technology,..

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Association Between Early Change in Arterial Carbon Dioxide Tension and Outcomes in Neonates Treated by Extracorporeal Membrane Oxygenation

Abstract The primary objective was to investigate the association between partial pressure of carbon dioxide (PaCO2) change after extracorporeal membrane oxygenation (ECMO) initiation and neurologic outcome in neonates treated for respiratory..

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Extracorporeal versus conventional cardiopulmonary resuscitation for refractory out‑of‑hospital cardiac arrest: a secondary analysis of the Prague OHCA trial

Abstract Background: Survival rates in refractory out-of-hospital cardiac arrest (OHCA) remain low with conventional advanced cardiac life support (ACLS). Extracorporeal life support (ECLS) implantation during ongoing resuscitation, a method called..

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Single-Center Experience With a Self-Expandable Venous Cannula During Minimally Invasive Cardiac Surgery

Abstract Objective: Venous drainage is often problematic in minimally invasive cardiac surgery (MICS). Here, we describe our experience with a self-expandable stent cannula designed to optimize venous drainage. Methods: The smart canula® was used..

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Continuous field flooding versus final one-shot CO2 insufflation in minimally invasive mitral valve repair

Abstract Background Insufflation of carbon dioxide (CO2) into the operative field to prevent cerebral or myocardial damage by air embolism is a well known strategy in open-heart surgery. However, here..

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The arresting LVAD patient: A review of the updated recommendations

By Stephanie Louka, MD Case scenario: Paramedics are called to the home of a 59-year-old male patient with an LVAD who was found unconscious and unresponsive by family members. He..

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Pump up the volume

Abstract Assessment and treatment of a patient with a  (VAD) is slightly different than what is expected in any other patient out there. Let’s look at what we need to know..

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Higher Mean Arterial Pressure during Cardiopulmonary Bypass May Not Prevent Acute Kidney Injury in Elderly Patients Undergoing Cardiac Surgery

Abstract We aimed to evaluate the role of higher mean arterial pressure (MAP) during cardiopulmonary bypass (CPB) in preventing development of acute kidney injury (AKI).  Methods. We evaluated a population..

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