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Neuromonitoring and Neurocognitive Outcomes in Cardiac Surgery: A Narrative Review

Abstract Neurocognitive dysfunction after cardiac surgery can present with diverse clinical phenotypes, which include , postoperative , and stroke, and it presents a significant healthcare burden for both patients and providers. Neurologic..

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Assessments of microvascular function in organ systems

Abstract Microvascular disease plays critical roles in the dysfunction of all organ systems, and there are many methods available to assess the microvasculature. These methods can either assess the target..

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Perioperative Quality Initiative and Enhanced Recovery After Surgery-Cardiac Society Consensus Statement on the Management of Preoperative Anemia and Iron Deficiency…

Abstract Preoperative anemia is common in patients presenting for cardiac surgery, with a prevalence of approximately 1 in 4, and has been associated with worse outcomes including increased risk of..

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The Use of Cerebral Oximetry in Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Abstract Objective The evidence on the use of cerebral  during surgery to minimize postoperative  remains uncertain in the literature. The present authors aimed to assess the value of cerebral  in the..

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Serious hazards of transfusion: evaluating the dangers of a wrong patient autologous salvaged blood in cardiac surgery

Abstract Background The past half century has seen the near eradication of transfusion-associated hazards. Intraoperative cell salvage while widely used still poses significant risks and hazards due to human error...

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Microplegia in paediatric hearts

Abstract Introduction A basic prerequisite for a good surgical outcome in heart surgery is optimal myocardial protection. However, cardioplegia strategies used in adult cardiac surgery are not directly transferable to..

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Use of two parallel oxygenators during veno-venous extracorporeal membrane oxygenation in a patient with severe obesity and COVID-19 pneumonia

Abstract Background: Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) is one effective treatment for COVID-19 pneumonia, but controversy regarding VV-ECMO management in obese patients still exists. In this report, we described a case..

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Superior restoration of left ventricular performance after prolonged single-dose del Nido cardioplegia in conjunction with terminal warm blood cardioplegic reperfusion

Abstract Objectives An incomplete restoration of  after del Nido  was noted in our recent study. This study tested the hypothesis that terminal warm blood  promotes a prompt restoration of  after a prolonged single-dose del..

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Risk factors for postoperative delirium on oxygen delivery-guided perfusion

Abstract Background Studies have demonstrated the efficacy of oxygen delivery-guided perfusion (ODGP) in preventing postoperative acute kidney injury, but the benefit of ODGP for delirium has not been confirmed. We..

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Critical Preoperative Hemoglobin Value to Predict Anemia-Related Complications After Cardiac Surgery

Abstract Objectives Preoperative anemia is frequent in patients undergoing cardiac surgery and is associated with increased postoperative complications.  Design A retrospective observational cohort study. Setting A tertiary-care medical center from..

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Extracorporeal Support for Acute Respiratory Distress Syndrome in Adults

Abstract There is a subset of patients who develop severe ARDS for whom supportive care with mechanical ventilation is insufficient or possibly injurious. The use of ECMO as an adjunct..

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One-Year Mental and Physical Health Assessment in Survivors After ECMO for COVID-19-related ARDS

Abstract Rational. Long-term outcomes of patients with COVID-19-related acute respiratory distress syndrome (ARDS) treated with extracorporeal membrane oxygenation (ECMO) are unknown. Methods. Multicenter, prospective study in patients who received ECMO..

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Hemolysis during Pediatric Extracorporeal Membrane Oxygenation: Associations with Circuitry, Complications, and Mortality

Abstract Objective: To describe factors associated with hemolysis during pediatric extracorporeal membrane oxygenation (ECMO), and the relationships between hemolysis, complications and mortality. Design: Secondary analysis of data collected prospectively by..

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Comparison of del Nido and histidine-tryptophan-ketoglutarate cardioplegic solutions in minimally invasive cardiac surgery

Abstract Objective We examined the safety and efficacy of del Nido  compared with histidine-tryptophan-ketoglutarate  in . Methods Patients who underwent  using del Nido or histidine-tryptophan-ketoglutarate from 2015 to 2019 were enrolled. Various clinical outcomes..

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Early MCS with Impella® and V-A ECMO in Refractory Cardiogenic Shock

  Jörn Tongers, MD, discusses his recently published paper evaluating the efficacy and safety of early combined mechanical circulatory support (MCS) with an Impella® heart pump and venoarterial extracorporeal membrane..

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Prediction of acute kidney injury risk after cardiac surgery: using a hybrid machine learning algorithm

Abstract Background Acute kidney injury (AKI) is a serious complication after cardiac surgery. We derived and internally validated a Machine Learning preoperative model to predict cardiac surgery-associated AKI of any severity and..

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Unilateral versus bilateral anterograde cerebral perfusion in acute type A aortic dissection repair: A systematic review and meta-analysis

Abstract Objectives: The aim of the study is to compare the safety and efficacy of unilateral anterograde cerebral perfusion (UACP) and bilateral anterograde cerebral perfusion (BACP) for acute type A..

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Impact of gender differences on hemostasis in patients after coronary artery bypass grafts surgeries in the context of tranexamic acid…

Abstract Background Sex differences present in the blood management of patients after coronary artery bypass grafts (CABG) surgeries. Tranexamic acid (TXA) performed well in maintaining hemostasis during and after surgeries...

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Management of Patients at Risk for and With Left Ventricular Thrombus: A Scientific Statement From the American Heart Association

Abstract Despite the many advances in cardiovascular medicine, decisions concerning the diagnosis, prevention, and treatment of left ventricular (LV) thrombus often remain challenging. There are only limited organizational guideline recommendations..

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Red Blood Cell Transfusion and Postoperative Infection in Patients Having Coronary Artery Bypass Grafting Surgery: An Analysis of the Society…

Abstract BACKGROUND:  Coronary artery bypass grafting (CABG) is the most common cardiac surgical procedure in the world and up to one-third of patients are transfused red blood cells (RBCs). RBC..

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In vitro elimination of gaseous microemboli utilizing hypobaric oxygenation in the Terumo® FX15 oxygenator

Abstract Background: This study examines the efficacy of hypobaric oxygenation as it relates to the elimination of gaseous microemboli (GME) at designated flow, pressure and temperature combinations. Methods: Hypobaric oxygenation..

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Assessment of Perioperative Outcomes Among Surgeons Who Operated the Night Before

Abstract Importance  The association between physician fatigue and patient outcomes is important to understand but has been difficult to examine given methodological and data limitations. Surgeons frequently perform urgent procedures overnight..

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Doxycycline can reduce glycocalyx shedding by inhibiting matrix metalloproteinases in patients undergoing cardiopulmonary bypass: A randomized controlled trial

Abstract Background Cardiopulmonary bypass (CPB) leads to shedding of the glycocalyx of endothelial cells, resulting in a series of complications such as tissue edema and coagulatory and microcirculatory dysfunctions. Matrix..

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Predictors of health-related quality of life after cardiac surgery: a systematic review

Abstract Background Health-related quality of life (HRQoL) is important in determining surgical success, particularly from the patients’ perspective. Aims To identify predictors for HRQoL outcome after cardiac surgery in order..

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Anomalous inferior vena cava drainage in a patient undergoing cardiac surgery

Abstract Congenital anomalies of the inferior vena cava are rare but if unidentified may create a risk for complications during surgery. In cardiac surgery, identifying such anomalies is crucial as..

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Autotransfusion in low-resource settings: a scoping review

Abstract Introduction Globally, haemorrhage is the leading cause of both maternal mortality and preventable trauma death. For patients suffering from haemorrhage, prompt blood transfusion can be life-saving; however, safe and sufficient..

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Modified Branch-first Open Repair of Thoracoabdominal aortic aneurysm- A technical Description

Abstract The current conventional open TAAA repairs are performed by select centers around the world with good outcomes. However, lesser experienced centers often encounter difficulties in replicating similar results of..

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Effect of Hemadsorption Therapy in Critically Ill Patients with COVID-19 (CYTOCOV-19): A Prospective Randomized Controlled Pilot Trial

Abstract Introduction: Immunomodulatory therapies have shown beneficial effects in patients with severe COVID-19. Patients with hypercytokinemia might benefit from the removal of inflammatory mediators via hemadsorption. Methods: Single-center prospective randomized trial at..

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Complications Associated With Venovenous Extracorporeal Membrane Oxygenation—What Can Go Wrong?

Abstract Objectives:  Despite increasing use and promising outcomes, venovenous extracorporeal membrane oxygenation (V-V ECMO) introduces the risk of a number of complications across the spectrum of ECMO care. This narrative review describes..

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Clinical and echocardiographic predictors of the anterior mitral leaflet repair failure

Abstract Background Anterior mitral leaflet prolapse repair is a highly effective procedure, but despite excellent operative results still has an inferior long-term durability when compared to posterior leaflet repair. Methods..

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