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Real-Time Evaluation of Cerebral Autoregulation Based on Near-Infrared Spectroscopy to Predict Clinical Outcome after Bypass Surgery in Moyamoya Disease

Abstract Impaired cerebral autoregulation (CA) can cause negative outcomes in neurological conditions. Real-time CA monitoring can predict and thereby help prevent postoperative complications for neurosurgery patients, especially those suffering from..

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Aortic arch replacement with simultaneous antegrade cerebral and systemic perfusion using a single centrifugal pump driven ‘split arterial line’ extracorporeal…

Abstract The ability to provide antegrade cerebral and systemic perfusion simultaneously may negate the requirement for any prolonged period of circulatory arrest during complex aortic arch reconstruction procedures, depending on..

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Association Between Plasma Fibrinogen Concentration After Cardiopulmonary Bypass and Postoperative Blood Loss in Children Undergoing Cardiac Surgery: A Retrospective Cohort…

Abstract Background Intraoperative hypofibrinogenemia is a major factor associated with increased postoperative blood loss in adult cardiac surgery. However, previous pediatric studies on this topic did not sufficiently adjust for..

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Oxygen Delivery Thresholds During Cardiopulmonary Bypass and Risk for Acute Kidney Injury

Abstract Background Postoperative acute kidney injury (AKI) in cardiac surgery patients is multifactorial and associated with low oxygen delivery (DO2) during cardiopulmonary bypass. Methods Cardiac surgical patients undergoing full cardiopulmonary..

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Correlations between the Circulating Level of Cell-Derived Microparticles and Surgical Variables in Heart Valve Surgery with Cardiopulmonary Bypass

Abstract Background: Cell-derived microparticles (MPs) as membrane vesicles are procoagulant. They play a role in surgical hemostasis. In this study, the correlations between the circulating level of cell-derived MPs and..

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ABO Blood Group and Bleeding and Survival in VA-ECMO Patients

Abstract ABO blood group has been shown to be a major determinant of plasma von Willebrand factor (vWF) levels. O blood group is associated with the lowest vWF levels and..

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Effect of lactate levels on extubation time in coronary artery bypass grafting surgery

Abstract Aim: In current practice, fast-track protocols are gaining importance in patients undergoing cardiac surgery. For this purpose, besides different application techniques, biomarkers are frequently examined in the peri-operative period...

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Project S.T.O.P (Stop the Over-ordering of Platelets): An initiative to reduce platelet wastages for pediatric open-heart surgeries

Abstract Introduction Due to a national policy change in the management of unused platelet units from September 2018, there was a drastic increase in the number of platelet units wasted..

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Circuit change during extracorporeal membrane oxygenation: single-center retrospective study of 48 changes

Abstract Background Bleeding and thrombosis induce major morbidity and mortality in patients under extracorporeal membrane oxygenator (ECMO). Circuit changes can be performed for oxygenation membrane thrombosis but are not recommended..

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Validation of a new model of selective antegrade cerebral perfusion with circulatory arrest in rats

Abstract Background Selective antegrade cerebral perfusion (SACP) is adopted as an alternative to deep hypothermic circulatory arrest (DHCA) during aortic arch surgery. However, there is still no preclinical evidence to..

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Outcomes of patients with respiratory failure declined for extracorporeal membrane oxygenation: a prospective observational study

Abstract Purpose Descriptive information on referral patterns and short-term outcomes of patients with respiratory failure declined for extracorporeal membrane oxygenation (ECMO) is lacking. Methods We conducted a prospective single-centre observational..

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Factors contributing to preventing operating room “never events”: a machine learning analysis

Abstract Background A surgical “Never Event” is a preventable error occurring immediately before, during or immediately following surgery. Various factors contribute to the occurrence of major Never Events, but little..

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Requirements for implementing a ‘just culture’ within healthcare organisations: an integrative review

Abstract Purpose To identify requirements for implementing a ‘just culture’ within healthcare organisations. Methods Using Whittemore and Knafl’s methodology for integrative reviews, we searched PubMed, PsychInfo, Cumulative Index of Nursing and Allied..

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Congenital cardiac surgery in a patient with cold agglutinins

Abstract Cold agglutinin disease is a type of autoimmune haemolytic anaemia caused by autoantibodies that bind to red blood cell antigens at a cold temperature and causes extravascular haemolysis and..

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Development and Validation of a Nomogram for Predicting Heparin Resistance in Neonates and Young Infants Undergoing Cardiac Surgery: A Retrospective…

Abstract BACKGROUND:  Heparin resistance (HR) is a common finding in pediatric cardiac surgery and generally refers to decreased sensitivity to heparin. Antithrombin (AT) deficiency is considered the primary mechanism of..

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The interaction of thrombocytopenia, hemorrhage, and platelet transfusion in venoarterial extracorporeal membrane oxygenation: a multicenter observational study

Abstract Background Thrombocytopenia, hemorrhage and platelet transfusion are common in patients supportedwith venoarterial extracorporeal membrane oxygenation (VA ECMO). However, current literature is limited to smallsingle‑center experiences with high degrees of..

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Mechanical Ventilation during ECMO: Best Practices

Abstract Adults and children who require extracorporeal membrane oxygenation for respiratory failure remain at risk for ongoing lung injury if ventilator management is not optimized. This review serves as a..

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Impact of prophylactic intra-aortic balloon pump on early outcomes in patients with severe left ventricular dysfunction undergoing elective coronary artery…

Abstract Objective Our aim was to analyse whether prophylactic preoperative intraaortic balloon pump (IABP) improves outcomes in hemodynamically stable patients with low  (LVEF ≤30%) undergoing elective  (CABG) using  (CPB). Secondary aim was to..

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Comparison of complement consumption and platelet accumulation between membrane oxygenators coated with a polymer or heparin

Abstract Introduction The membrane oxygenator in extracorporeal circulation circuits is coated with acrylate-copolymer (ACP) or immobilized heparin (IHP) to enhance hemocompatibility. To evaluate the relative features of both coatings, we..

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Pro: Can We Use Artificial Intelligence-Derived Algorithms to Guide Patient Blood Management Decision-Making?

Abstract What are AI, Machine Learning, and Artificial Neural Networks? Medical publishing in AI has increased exponentially over the last few years.7 Artificial intelligence is a broad term that represents the..

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Con: Artificial Intelligence–Derived Algorithms to Guide Perioperative Blood Management Decision Making

Abstract Artificial intelligence has the potential to improve the care that is given to patients; however, the predictive models created are only as good as the base data used in..

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Organ Donation After Out-of-Hospital Cardiac Arrest: A Scientific Statement From the International Liaison Committee on Resuscitation

Abstract Aim of the Review: Improving rates of organ donation among patients with out-of-hospital cardiac arrest who do not survive is an opportunity to save countless lives. The objectives of..

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Interest Grows in LAVA-ECMO

Abstract LAVA-ECMO has recently gained attention in the medical community, specifically, as support for cardiogenic-shock patients. In particular, interest has picked up since it was highlighted at the 2023 Houston..

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Tricuspid Regurgitation Management for Heart Failure

Abstract There is growing evidence that severe tricuspid regurgitation (TR) impacts clinical outcomes in a variety of cardiovascular disease states. The late presentation of patients with advanced TR highlights the..

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Which Vasopressors and Inotropes to Use in the Intensive Care Unit

Abstract Introduction Cardiac output (CO) is a key determinant of oxygen delivery. Low cardiac output syndrome (LCOS) causes organ dysfunction, prolonged hospital stay, and reduces survival in perioperative settings and..

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Tissue perfusion pressure enables continuous hemodynamic evaluation and risk prediction in the intensive care unit

Abstract Treatment of circulatory shock in critically ill patients requires management of blood pressure using invasive monitoring, but uncertainty remains as to optimal individual blood pressure targets. Critical closing pressure,..

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Trends on Near-Infrared Spectroscopy Associated With Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation

Abstract We aimed to determine the association between cerebral regional oxygen saturation (rSO2) trends from cerebral near-infrared spectroscopy (cNIRS) and acute brain injury (ABI) in adult venoarterial extracorporeal membrane oxygenation (VA-ECMO) patients. ABI was defined as..

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Superiority of the Ross procedure over other valve substitutes in the paediatric population: this is only the beginning

Abstract The times are changing for the Ross procedure as it settles itself as the best alternative for valve replacement not only in young adults, but also, as the study..

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Defibrillation Strategies for Refractory Ventricular Fibrillation

Abstract BACKGROUND Despite advances in defibrillation technology, shock-refractory ventricular fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external defibrillation (DSED; rapid sequential shocks from two defibrillators) and vector-change (VC)..

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The First Autoregulated Total Artificial Heart Implant in the United States

Abstract The Aeson total artificial heart provides right- and left-sided heart replacement for biventricular failure with notable improvements from prior generations. These include enhanced hemocompatibility and autoregulation enabling increased output in..

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