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Extracorporeal life support in thoracic emergencies—a narrative review of current evidence

Abstract Background and Objective: Resuscitative therapies for respiratory and cardiac failure are lifesaving and extended by using extracorporeal life support (ECLS) as mechanical circulatory support (MSC). This review informs the debate..

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Mechanical life support algorithm for the emergency management of patients with left-sided Impella

Abstract We sought to remedy the limited guidance that is available to support the resuscitation of patients with the Impella Cardiac Power (CP) and 5.0 devices during episodes of cardiac..

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Secondary tricuspid valve regurgitation after isolated aortic valve replacement: outcomes and predictors

Abstract OBJECTIVES We sought to assess the evolution of secondary tricuspid regurgitation (TR) after isolated aortic valve replacement (AVR) and its impact on mortality and to identify possible clinical and..

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Effective Treatment of Acute Tricyclic Antidepressant Poisoning with Cardiogenic Shock and Severe Rhabdomyolysis Using ECMO and CytoSorb® Adsorber

Abstract BACKGROUND Tricyclic antidepressant (TCA) drugs are a common cause of fatal poisoning because of their cardiotoxic and arrhythmogenic effects. Classic supportive management includes sodium bicarbonate, gastrointestinal chelating agents, and..

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Mycobacterium abscessus Cluster in Cardiac Surgery Patients Potentially Attributable to a Commercial Water Purification System

Abstract Background: Nontuberculous mycobacteria are water-avid pathogens that are associated with nosocomial infections. Objective: To describe the analysis and mitigation of a cluster of Mycobacterium abscessus infections in cardiac surgery patients. Design:..

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Cannulation for veno-venous extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is described as a modified, smaller cardiopulmonary bypass circuit. The veno-venous (VV) ECMO circuit drains venous blood, oxygenate the blood, and pump the blood back..

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Superior vena cava drainage improves upper body oxygenation during veno-arterial extracorporeal membrane oxygenation in sheep

Abstract Introduction Differential hypoxia is a pivotal problem in patients with femoral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) support. Despite recognition of differential hypoxia and attempts to deliver more oxygenated..

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Bicaval dual-lumen cannula for venovenous extracorporeal membrane oxygenation: Avalon© cannula in childhood disease

Abstract Severe acute refractory respiratory failure is considered a life-threatening situation, with a high mortality of 40 to 60%. When conservative oxygenation methods fail, a lifesaving measure is the introduction..

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Extracorporeal cytokine adsorption reduces systemic cytokine storm and improves graft function in lung transplantation

Abstract Objectives Ischemia–reperfusion injury often coincides with a , which can result in  following . Our previous research has demonstrated  improvement by cytokine adsorption during ex vivo lung perfusion. The aim of this study was..

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Five commercial ‘depth of anaesthesia’ monitors provide discordant clinical recommendations in response to identical emergence-like EEG signals

Abstract Background ‘Depth of anaesthesia’ monitors claim to measure hypnotic depth during general anaesthesia from the EEG, and clinicians could reasonably expect agreement between monitors if presented with the same..

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Position of draining venous cannula in extracorporeal membrane oxygenation for respiratory and respiratory/circulatory support in adult patients

Abstract Extracorporeal membrane oxygenation (ECMO) is used in critically ill patients with severe pulmonary and/or cardiac failure. Blood is drained from the venous system and pumped through a membrane oxygenator..

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Optimal Position of a Femorojugular Cannulation for Venovenous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome

Abstract Background: This study aimed to determine the optimal position of venovenous extracorporeal membrane oxygenation (V-V ECMO) draining cannulas for refractory respiratory failure based on short-term clinical results. Methods: In total, 278..

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The ProtekDuo in percutaneous peripheral venopulmonary-arterial ECMO and PROpella configuration for cardiogenic shock with biventricular failure

Abstract This article describes a case study where a patient with ProtekDuo + oxygenator and Impella CP (PROpella) in biventricular failure and cardiogenic shock was reconfigured to venopulmonary-arterial (VP-A) extracorporeal..

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Association between pediatric intensive care mortality and mechanical ventilation settings during extracorporeal membrane oxygenation for pediatric acute respiratory distress syndrome

Abstract The main objective of this study was to describe the current mechanical ventilation (MV) settings during extracorporeal membrane oxygenation (ECMO) for pediatric acute respiratory distress syndrome (P-ARDS) in six..

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ECPR for refractory OHCA – lessons from 3 randomized controlled trials. The trialists´view

Abstract Extracorporeal cardiopulmonary resuscitation is a promising treatment for refractory out-of-hospital cardiac arrest. Three recent randomized trials (ARREST-trial, Prague OHCA study, and INCEPTION-trial) that addressed the clinical benefit of ECPR..

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Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients

Abstract Objective The purpose of this study was to explore the relationship between platelet concentration (PLT) (× 109/L) and clot strength measured by  maximum amplitude (TEG-MA) in healthy volunteers without a..

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Endothelial and Hemodynamic Function in a Large Animal Model in Relation to Different Extracorporeal Membrane Oxygenation Cannulation Strategies and Intra-Aortic…

Abstract Background: The use of simultaneous veno-arterial extracorporeal membrane oxygenation (ECMO) with or without an Intra-Aortic Balloon Pump (IABP) is a widely used tool for mechanical hemodynamic support. Endothelial function,..

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Early United States experience with lung donation after circulatory death using thoracoabdominal normothermic regional perfusion

Abstract Thoracoabdominal normothermic  (TA-NRP) has recently begun being utilized in the United States for recovery of   from some  after circulatory death (DCD), but data on lungs recovered in this method is limited to ...

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Artificial intelligence-based early detection of acute kidney injury after cardiac surgery

Abstract OBJECTIVES This study aims to improve the early detection of cardiac surgery-associated acute kidney injury using artificial intelligence-based algorithms. METHODS Data from consecutive patients undergoing cardiac surgery between 2008..

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Unleashing the Power of Gamification

Curious about why we chose to develop a video game instead of a mere online simulator? We receive this question frequently, so let us share with you a few compelling..

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FAQs about virCPB

Your Ultimate Guide to Get to Know virCPB Welcome to the world of virCPB, where education meets gaming to revolutionize the way perfusion students and perfusionists train and master their..

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Venovenous Extracorporeal Membrane Oxygenation Initiation for Pediatric Acute Respiratory Distress Syndrome With Cardiovascular Instability is Associated With an Immediate and…

Abstract Objective:  To determine the association of venovenous extracorporeal membrane oxygenation (VV-ECMO) initiation with changes in vasoactive-inotropic scores (VISs) in children with pediatric acute respiratory distress syndrome (PARDS) and cardiovascular instability. Design:  Retrospective cohort..

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Impact of the Pediatric ABO Policy Change on Listings, Transplants, and Outcomes for Children Younger Than 2 Years Listed for…

Abstract Background: We assessed the impact of the liberalized ABO pediatric policy change on candidate characteristics and outcomes for children undergoing heart transplant (HT). Methods and results: Children <2 years undergoing HT..

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Venovenous Extracorporeal CO2 removal to support ultraprotective ventilation in moderate-severe ARDS: A systematic review and meta-analysis of the literature

Abstract Background A strategy that limits tidal volumes and inspiratory pressures, improves outcomes in patients with the acute respiratory distress syndrome (ARDS). Extracorporeal carbon dioxide removal (ECCO2R) may facilitate ultra-protective ventilation...

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Unilateral Versus Bilateral Antegrade Cerebral Protection During Aortic Surgery: An Updated Meta-Analysis

Abstract Background: In the context of complex aortic surgery, despite the wide consensus about the use of moderate hypothermia in association with antegrade selective cerebral perfusion (ASCP), its bilateral administration is..

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An Unusual Case of Left Ventricular Free Wall Rupture Caused by a Silent Myocardial Infarction

Abstract Left ventricular free wall rupture (LVFWR) is a serious complication of myocardial infarction. It presents with a very high mortality rate and can be rescued by accurate diagnosis and..

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Aortic root thrombus causing non-ST elevation myocardial infarction after left ventricular assist device

Abstract A 61-year-old male presented with a history of ischemic cardiomyopathy requiring left ventricular assist device (LVAD) implantation 9 months prior to presentation. The patient was on aspirin and warfarin..

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Outcomes in trauma patients undergoing veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome

Abstract Background: The use of veno-venous extracorporeal membrane oxygenation (VV ECMO) remains controversial in trauma patients with acute respiratory distress syndrome (ARDS). Here, we aimed to investigate the therapeutic benefits..

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3 myths about ECMO that are costing hospitals and patients

Abstract Although the global pandemic is officially over, it has left a permanent mark on the health care landscape, reshaping the dynamics of hospitals in the United States. While staffing..

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Dual lumen cannulation and mobilization of patients with venovenous extracorporeal membrane oxygenation

Abstract Background Mobilization is important in longer courses in intensive care unit (ICU), typical for patients requiring venovenous extracorporeal membrane oxygenation (V-V ECMO). For patients supported with ECMO, especially out-of-bed..

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