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Methemoglobin as a marker of acute anemic stress in cardiac surgery

Abstract Biological evidence supports plasma methemoglobin as a biomarker for anemia-induced tissue hypoxia. In this translational planned substudy of the multinational randomized controlled transfusion thresholds in cardiac surgery (TRICS-III) trial,..

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Effect of Cardiopulmonary Bypass on SARS‐CoV‐2 Vaccination Antibody Levels

Abstract Background Adults undergoing heart surgery are particularly vulnerable to respiratory complications, including COVID‐19. Immunization can significantly reduce this risk; however, the effect of cardiopulmonary bypass (CPB) on immunization status..

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Encouraging results of blood conservation in neonatal open-heart surgery

Abstract Objective To report early outcomes of blood conservation in neonatal open-heart surgery. Methods Ninety-nine patients undergoing neonatal open-heart surgery during the implementation of a blood conservation program between May..

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Patient Safety 2.0: Slaying Dragons, Not Just Investigating Them

Abstract The purpose of patient safety work is to reduce avoidable patient harm. This requires us to slay dragons—to eliminate or at least mitigate risks to patients. Instead, current practice focuses..

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Hydroxocobalamin Versus Methylene Blue for the Treatment of Vasoplegic Shock Associated With Cardiopulmonary Bypass

Abstract Objectives To compare changes in vasopressor requirements and hemodynamic responses after hydroxocobalamin or methylene blue administration for vasoplegic shock (VS). Design Retrospective cohort analysis. Setting Single-center, academic medical center...

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The beneficial use of nitric oxide during cardiopulmonary bypass on postoperative outcomes in children and adult patients: a systematic review…

Abstract Purpose Investigate inhaled nitric oxide’s influence on mortality rates, mechanical ventilation and cardiopulmonary bypass duration, and length of stay in the intensive care unit and hospital when administered during..

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Pulmonary Vasodilator and Inodilator Drugs in Cardiac Surgery: A Systematic Review With Bayesian Network Meta-Analysis

Abstract Objective The authors performed a systematic review to evaluate the effect of pharmacologic therapy on pulmonary hypertension in the perioperative setting of elective cardiac surgery (PROSPERO CRD42023321041). Design Systematic..

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Incorporating a Patient Safety and Quality Course Into the Nursing Curriculum: An Assessment of Student Gains

Abstract Background  Training nursing students on quality and patient safety (PS) is crucial to ensuring safe healthcare practices given the key role nurses play on the healthcare team. The aim..

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The Additional Cost of Perioperative Medication Errors

Abstract The purpose of this report was to estimate the additional annual cost to the U.S. healthcare system attributable to preventable medication errors (MEs) in the operating room. The ME..

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Relationship between estimated and observed heparin sensitivity indices in cardiac and thoracic aortic surgery

Abstract Background Little evidence exists on the relationship between the estimated heparin sensitivity index (HSI) based on commonly available clinical and laboratory data and observed HSI in the adult population...

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Simultaneous Cesarean Section and Maternal Cardiac Surgery: Outcomes and Feasibility from a Tertiary Care Hospital in India

Abstract Introduction Cardiovascular disease is the leading cause of pregnancy-related mortality, and it has gradually increased over time; this rise has been attributed to numerous reasons including the growing number..

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Pro: Individualized optimal perfusion pressure- Maximizing Patient Care during Cardiopulmonary Bypass

Abstract Cardiopulmonary bypass (CPB) has revolutionized cardiac surgery but poses challenges such as hemodynamic instability and adverse clinical outcomes. Achieving optimal perfusion during CPB ensures adequate oxygen delivery to vital..

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Central Extracorporeal Membrane Oxygenation Support Following Calcium Channel Blocker Overdose in Children

Abstract Refractory vasodilatory shock (RVS) following massive calcium channel blocker (CCB) overdose remains a challenging clinical entity. Peripheral venoarterial extracorporeal membrane oxygenation (ECMO) has proven useful in several cases of..

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Impact of age on survival for patients receiving ECPR for refractory out-of-hospital VT/VF cardiac arrest

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to improve neurologically favorable survival for patients with refractory ventricular tachycardia (VT)/ventricular fibrillation (VF) out-of-hospital cardiac arrest. Prior studies of the impact of age..

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Biofilm Assessment and Metagenomic Analysis of Venoarterial Extracorporeal Membrane Oxygenation Cannulas and Membrane Oxygenators

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) exposes the patient to infectious complications related to the cannulas or the site of insertion. The aim of the current study was to investigate..

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Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomised controlled trials and propensity score matched studies.

Abstract Background: Cardiogenic shock is associated with high mortality. In refractory shock, it is unclear if mechanical circulatory support (MCS) devices improve survival. We conducted a systematic review and network meta-analysis..

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Changes in Cerebral Regional Oxygen Saturation Variability in Neonates Undergoing Cardiac Surgery: A Prospective Cohort Study

Abstract Near-infrared spectroscopy is routinely used in the monitoring of cerebral regional oxygen saturation (crSO2) in neonates following congenital heart surgery. Decreased postoperative crSO2 variability in these patients is associated with..

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Epidemiology of ischemic stroke and hemorrhagic stroke in venoarterial extracorporeal membrane oxygenation

Abstract Background While venoarterial extracorporeal membrane oxygenation (V‑A ECMO) provides lifesaving supportfor cardiopulmonary failure, complications may increase mortality, with few studies focusing on ischemic/hemor‑rhagic stroke. We aimed to determine the..

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ECMO as an Indirect Bridge to Durable Left Ventricular Assist Device Implantation

Abstract Introduction: The need for preoperative extracorporeal membrane oxygenation (ECMO) support prior to left ventricular assist device(LVAD) therapy has been associated with increased mortality. Our study investigated the impact of de-escalating..

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Extracorporeal Membrane Oxygenation Without Invasive Ventilation for Respiratory Failure in Adults: A Systematic Review

Abstract OBJECTIVES:  Extracorporeal membrane oxygenation (ECMO) is an advanced treatment for acute severe respiratory failure. Patients on ECMO are frequently maintained sedated and immobilized until weaning from ECMO, first, and..

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Heparin consumption and inflammatory response according to the coating of cardiopulmonary bypass circuits in cardiac surgery: A retrospective analysis

Abstract Introduction There are several types of surface treatments (coatings) aimed at improving the biocompatibility of cardiopulmonary bypass (CPB) circuit. Some coatings appear to require higher doses of heparin to..

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Physiology-Based Indications to Improve Outcome of Awake Extracorporeal Membrane Oxygenation

Abstract Acute hypoxemic respiratory failure (AHRF) and its more severe form, acute respiratory distress syndrome (ARDS), imply a decrease in the ability to exchange oxygen and carbon dioxide by the..

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Outcomes of Recipients Aged 65 Years and Older Bridged to Lung Transplant With Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplant (BTT) has been used for critically ill candidates with excellent outcomes, but data on this strategy in older recipients..

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A Novel Approach to Measuring Physiologic Changes during Ambulation for a Patient with Post Infarct VSD Supported on Femoral IABP…

Abstract Post-infarct ventricular septal defect (PIVSD) is a rare, life-threatening complication following acute myocardial infarction (MI), associated with high overall mortality. Interventions include medical management, percutaneous closure, and/or surgical closure...

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Obesity is Associated with Increased Mortality in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) is used to support patients with cardiac and respiratory failure. The relationship between obesity and VA-ECMO outcomes is unknown. Objectives: To determine the relationship between..

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Tranexamic Acid for Bleeding Management in Adult Patients on Extracorporeal Membrane Oxygenation

Abstract This study described the outcomes of patients receiving topical, nebulized, endobronchial, or systemic tranexamic acid (TXA) for bleeding events while on extracorporeal membrane oxygenation (ECMO). We performed a single-center..

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A new hematologic predictor of major adverse events after cardiac surgery: red cell distribution width to lymphocyte ratio

Abstract Background The perioperative risk factors that cause severe morbidity and prolongation of postoperative hospital stay after cardiac surgery should be determined. Various scores have been used to predict morbidity..

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Platelets and fibrinogen matter when bleeding on ECMO

Abstract We have read with interest the work by Helms et al., a single-center study with 30 patients (16 on veno-venous and 14 on veno-arterial extracorporeal membrane oxy-genation (ECMO)), with..

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Impella – Current issues and future expectations for the percutaneous, microaxial flow left ventricular assist device

Abstract Summary The importance of temporary mechanical circulatory support for treating acute heart failure with cardiogenic shock is increasingly recognized, and Impella (Abiomed, Danvers, MA, USA) has received particular attention..

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Using of the anesthetic gas filter CONTRAfluran© on cardio-pulmonary by-pass: Preliminary study of the feasibility, security and efficiency.

Abstract The two hypnotic agents currently used for the maintenance of general anesthesia during cardio-pulmonary bypass (CPB) are propofol and sevoflurane. Propofol can be administered directly in the cardiotome of..

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