Abstract Background Isolated limb perfusion (ILP) is a regional cancer treatment in which high-dose chemotherapy is administered in an isolated extremity. The main side effect is regional toxicity, which occasionally..
Read MoreAbstract Background Hypersensitivity reactions to heparin are uncommon conditions but pose a serious clinical problem for patients requiring cardiopulmonary bypass. Bivalirudin is a reversible direct thrombin inhibitor that can be..
Read MoreAbstract We present historical accounts of congenital heart surgery since the early 1900s, as our specialty evolved from individual heroic efforts into an established and sophisticated surgical specialty with consistent..
Read MoreAbstract Diseases affecting the aortic arch often require surgical intervention. Hypothermic circulatory arrest (HCA) enables a safe approach during open aortic arch surgeries. Additionally, HCA provides neuroprotection by reducing cerebral..
Read MoreAbstract A dysregulated host response is a common feature in critically ill patients due to both infectious and non-infectious origins that can lead to life-threatening organ dysfunction, which is still..
Read MoreAbstract Introduction Survival from refractory out of hospital cardiac arrest (OHCA) without timely return of spontaneous circulation (ROSC) utilising conventional advanced cardiac life support (ACLS) therapies is dismal. CHEER3 was..
Read MoreAbstract Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a life-saving therapy for critically ill patients, but it carries an increased risk of thrombosis due to blood interacting with non-physiological surfaces. While..
Read MoreAbstract Objectives Patients undergoing cardiac surgery often require , which are associated with increased morbidity and mortality. Patient blood management (PBM) strategies, including acute normovolemic (ANH), have been implemented to minimize allogeneic..
Read MoreAbstract Unfractionated heparin (UFH) is the most used anticoagulant in patients receiving veno-venous extracorporeal membrane oxygenation (VV-ECMO). Its therapeutic levels are monitored using activated partial thromboplastin time ratio (aPTTr) or..
Read MoreAbstract Background Burnout has gained increasing attention worldwide as a phenomenon that affects health care professionals. However, there is a lack of relevant research about its impact on practitioners in..
Read MoreAbstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is an effective mechanical circulatory support for cardiac insufficiency following cardiac surgery especially cardiac surgery with extracorporeal circulation, which can quickly restore the perfusion..
Read MoreAbstract The pathophysiology of post-cardiac arrest syndrome features ischaemic/reperfusion injury and the release of high levels of inflammatory cytokines [1]. These inflammatory markers include interleukin-6 (IL-6), C-reactive protein (CRP), tumour..
Read MoreAbstract Despite extracorporeal membrane oxygenation (ECMO) utilization in nearly 20% of cases, there are limited data in children with acute fulminant myocarditis (AFM) requiring ECMO. Herein we identify risk factors..
Read MoreAbstract A dysregulated host response is a common feature in critically ill patients due to both infectious and non-infectious origins that can lead to life-threatening organ dysfunction, which is still..
Read MoreAbstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) initiation for patients with cardiogenic shock or cardiac arrest is an attractive strategy since it provides a quick restoration of organ perfusion. One major..
Read MoreAbstract Primary graft dysfunction is a feared complication and cause of mortality post–heart transplant. Primary graft dysfunction may require mechanical circulatory support, such as venoarterial extracorporeal membrane oxygenation, which carries..
Read MoreAbstract The issue of left ventricular (LV) distention during venoarterial extracorporeal membrane oxygenation (VA-ECMO) is crucial as it markedly impacts on patients’ weanability and, ultimately, outcome. Numerous techniques have been..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is a form of temporary cardiopulmonary bypass for patients with acute respiratory or cardiac failure refractory to conventional therapy. Its usage has become increasingly widespread..
Read MoreAbstract Background: The so-called Low Cardiac Output Syndrome (LCOS) is one of the most common complications in pediatric patients with congenital heart disease undergoing corrective surgery. LCOS requires high..
Read MoreAbstract The term heparin resistance (HR) is used by clinicians without specific criteria. We performed a literature search and surveyed our SSC membership to better define the term when applied..
Read MoreAbstract Background Current medical simulators for extracorporeal membrane oxygenation (ECMO) are expensive and rely on low-fidelity methodologies. This creates a challenge that demands a new approach to eliminate high costs..
Read MoreAbstract The rising application of extracorporeal membrane oxygenation (ECMO) has emphasized the need for consistent and standardized terminology, especially concerning peripheral percutaneous cannulation of the pulmonary artery (PPC-PA). The Extracorporeal..
Read MoreAbstract Background Extracorporeal Membrane Oxygenation (ECMO) is a high-risk, low-volume procedure requiring repetition, skill and multiple disciplines with fidelity of communication. Yet many barriers exist to maintain proficiency and skills..
Read MoreAbstract BACKGROUND: Vaso-inotropic agents are frequently used to prevent and/or treat low cardiac output syndrome in infants undergoing surgery for congenital heart disease. Due to the lack of comparative studies,..
Read MoreAbstract Cardiogenic shock (CS) and cardiac arrest (CA) are among the most lethal complications of acute cardiovascular disease, affected by high in-hospital mortality rates. Venoarterial extracorporeal life support (VA ECLS)..
Read MoreAbstract Protamine, a highly basic protein isolated from salmon sperm, is the only clinically available agent to reverse the anticoagulation of unfractionated heparin. Following intravenous administration, protamine binds to heparin..
Read MoreAbstract The development of mechanical circulatory support (MCS) has been rapid, and its use worldwide in patients with cardiogenic shock is increasingly widespread. However, current statistical data and clinical research..
Read MoreAbstract Importance Prone positioning may improve outcomes in patients with severe acute respiratory distress syndrome (ARDS), but it is unknown whether prone positioning improves clinical outcomes among patients with ARDS who..
Read MoreAbstract Advanced Cardiac Life Support (ACLS) guidelines recommend a standardized approach to manage cardiac arrest, including cardiopulmonary resuscitation (CPR), defibrillation, and administration of drugs such as epinephrine [1]. Ultrasound (US)..
Read MoreAbstract Background The quality of a myocardial protection of a single-dose del Nido cardioplegia versus multiple dose blood-based cardioplegia on myocardial injury, outcomes and operative times in patients undergoing minimally..
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