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Long-Term Consequences of Acute Kidney Injury After Cardiac Surgery: A Systematic Review and Meta-Analysis

Abstract Objectives To determine the effect of  (AKI) associated with cardiac surgery on long-term mortality. Design Systematic review and meta-analysis of 9 observational studies extracted from the MEDLINE and EMBASE electronic..

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Nadir oxygen delivery during pediatric bypass as a predictor of acute kidney injury

Abstract Background Cardiac surgery associated acute kidney injury (CS-AKI) is common in infants and associates with negative outcomes. Nadir indexed oxygen delivery (DO 2i) during cardiopulmonary bypass (CPB) is associated with..

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Factors associated with acute kidney injury and mortality during cardiac surgery

Abstract Background Cardiac surgery with cardiopulmonary bypass (CPB) is known to contribute towards the incidence of acute kidney injury (AKI) and peri-operative morbidity and mortality. There are several patient, anaesthetic..

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A novel approach for monitoring volatile anesthetic concentration during cardiopulmonary bypass

Abstract To the Editor, Awareness and recall during general anesthesia is a rare yet serious complication that has been reported to occur in an estimated one in 8,600 cases of..

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Miniaturized versus conventional cardiopulmonary bypass and acute kidney injury after cardiac surgery

Abstract Introduction: Acute kidney injury (AKI) is a serious complication after coronary artery bypass grafting (CABG). There are conflicting reports whether a miniaturized cardiopulmonary bypass (MCPB) system is associated with..

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Levosimendan for Prevention of Acute Kidney Injury After Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials

Abstract Background Levosimendan has been shown to confer direct renoprotection in renal endotoxemic and ischemia-reperfusion injury and could increase renal blood flow in patients with low-cardiac-output heart failure. Results from..

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Acute Kidney Injury in Cardiac Surgery and Cardiac Intensive Care

Abstract Acute kidney injury (AKI) is a serious postoperative complication following cardiac surgery. Despite the incidence of AKI requiring temporary renal replacement therapy being low, it is nonetheless associated with..

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Global Incidence and Outcomes of Adult Patients With Acute Kidney Injury After Cardiac Surgery: A Systematic Review and Meta-Analysis

Abstract Objectives To estimate the global incidence and outcomes of  (AKI) after cardiac surgery in adult patients. Design A systematic review and meta-analysis. Setting Cardiac surgery wards. Participants Adult patients after..

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Successful Antithrombin Administration in Andexanet Alfa-Associated Heparin Resistance

Abstract Case Report A 72-year-old man with a tachycardiomyopathy, atrium flutter, and atrial fibrillation underwent an elective radiofrequency ablation procedure. In addition to 5 mg of apixaban twice daily, his..

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Vasopressinase Activity: A Potential Early Biomarker for Detecting Cardiopulmonary Bypass-Associated Acute Kidney Injury?

Abstract Background Acute kidney injury (AKI) is a common and serious complication of surgeries that include cardiopulmonary bypass (CPB). Currently, increases in serum creatinine levels are used to diagnose AKI,..

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Designing a new scoring system (QualyP Score) correlating the management of cardiopulmonary bypass to postoperative outcomes

Abstract Aim: The aim of this study was to ascertain if a score, directly derived from CPB records, could correlate to major postoperative outcomes. Methods: An additive score (QualyP Score)..

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Neonatal and Pediatric General and Cardiac Anaesthesia and ICU: what’s new in 2017/2018 ? -Bari Pediatric Hospital Experience-Italy

Abstract This review wants to give an overview to most of the controversial fields in the clinical therapeutic assistance in neonatal and pediatric general and cardiothoracic surgery in anaesthesia and..

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In vitro assays and clinical trials in red blood cell aging: Lost in translation

Abstract The age of  (EC) in  and the  when transfusing long-term-stored EC are highly controversial issues. Whereas the definition of a short-term-stored EC or a long-term-stored EC is unclear in clinical trials, data..

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Identification of Plasma Metabolites Prognostic of Acute Kidney Injury after Cardiac Surgery with Cardiopulmonary Bypass

Abstract Acute kidney injury (AKI) is a frequent complication after cardiopulmonary bypass, but early detection of postoperative AKI remains challenging. Protein biomarkers predict AKI excellently in homogeneous cohorts but are..

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Severe antiphospholipid syndrome and cardiac surgery: Perioperative management

Abstract Antiphospholipid syndrome is an antiphospholipid antibody-mediated prothrombotic state leading to arterial and venous thrombosis. This condition alters routine in-vitro coagulation tests, making results unreliable. Antiphospholipid syndrome patients requiring cardiac..

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Effect of nitric oxide on postoperative acute kidney injury in patients who underwent cardiopulmonary bypass: a systematic review and meta-analysis…

Abstract Background The effect of nitric oxide (NO) on renal function is controversial in critical illness. We performed a systematic meta-analysis and trial sequential analysis to determine the effect of..

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Establishing an ECMO program in a developing country: challenges and lessons learned

Abstract Aim: The ECMO (extracorporeal membrane oxygenation) Program at the American University of Beirut Medical Center was established in November 2015 as the first program serving adult and pediatric population..

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Association of genetic polymorphisms with acute kidney injury after cardiac surgery in a Southeast Asian population

Abstract Introduction Genetic polymorphisms are important in explaining the wide interpatient variability that exists in the development of acute kidney injury (AKI) post cardiac surgery. We hypothesised that polymorphisms in..

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Intravenous amino acid therapy for kidney protection in cardiac surgery patients: A pilot randomized controlled trial

Abstract Objective To determine whether a continuous  of standard amino acids could preserve kidney function after on-pump cardiac surgery. Methods Adult patients scheduled to receive cardiac surgery lasting longer than 1 hour..

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Postoperative Acute Kidney Injury in Young Adults With Congenital Heart Disease

Abstract Background There is an increasing number of young adults living with  (CHD). The goal of this study was to ascertain the frequency of  (AKI) as well as the risk factors and..

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Clinical impact of disinvestment in hydroxyethyl starch for patients undergoing coronary artery bypass surgery: a retrospective observational study

Abstract Purpose To examine the effect of discontinuing hydroxyethyl starch (HES) solutions on length of hospital stay, transfusion, risk of death, acute kidney injury (AKI), and dialysis. Methods We conducted..

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Successful Management of Massive Air Embolism During Cardiopulmonary Bypass Using Multimodal Neuroprotection Strategies

Abstract Complications and critical events during cardiopulmonary bypass (CPB) are very challenging, difficult to manage, and in some instances have the potential to lead to fatal outcomes. Massive cerebral air..

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Early negative fluid balance is associated with lower mortality after cardiovascular surgery

Abstract Background: Early fluid expansion could prevent postoperative organ hypoperfusion. However, excessive fluid resuscitation adversely influences multiple organ systems. This retrospective, observational study aimed to investigate the relationship between early..

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Pharmacological and non‐surgical renal protective strategies for cardiac surgery patients undergoing cardiopulmonary bypass: a systematic review

Abstract Background Post‐operative acute kidney injury after cardiopulmonary bypass (AKI‐CPB) for cardiac surgery is a frequent complication. It may require renal replacement therapy (RRT), which is associated with an increased..

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Fluid Management With Peritoneal Dialysis After Pediatric Cardiac Surgery

Abstract Children who undergo cardiac surgery with cardiopulmonary bypass are a unique population at high risk for postoperative acute kidney injury (AKI) and fluid overload. Fluid management is important in..

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Predictors of Postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery

Abstract Objective: The aims of this study were to identify the risk factors associated with acute kidney injury (AKI) after isolated surgical revascularization with cardiopulmonary bypass and to develop a..

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Validation of renal-risk models for the prediction of non-renal replacement therapy cardiac surgery-associated acute kidney injury

Abstract Background Cardiac surgery-associated acute kidney injury (AKI) is a serious complication of cardiac surgery, even when renal replacement therapy (RRT) is not required. The existing risk models for cardiac..

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Pre-operative level of FGF23 predicts severe acute kidney injury after heart surgery in children

Abstract Background Early detection of acute kidney injury (AKI) after cardiac surgery has improved recently with the discovery and validation of novel urinary biomarkers. However, objective tools to predict the..

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Nitric Oxide Decreases Acute Kidney Injury and Stage 3 Chronic Kidney Disease after Cardiac Surgery

Abstract Acute kidney injury (AKI) is a common and serious complication of cardiac surgical procedures that require prolonged (>90 min) cardiopulmonary bypass (CPB) (, ). Although the presence of AKI after..

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Addressing the challenges of ECMO simulation

Abstract Introduction/Aim: The patient’s condition and high-risk nature of extracorporeal membrane oxygenation (ECMO) therapy force clinical services to ensure clinicians are properly trained and always ready to deal effectively with..

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