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Perioperative Serum Free Hemoglobin and Haptoglobin Levels in Valvular and Aortic Surgery With Cardiopulmonary Bypass: Their Associations With Postoperative Kidney…

Abstract Highlights • Hemolysis due to CPB leads to an increase of serum free Hemoglobin(fHb) level. • Increase of serum fHb level had an independent association with postoperative AKI. •..

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STS/SCA/AmSECT/SABM Update to the Clinical Practice Guidelines on Patient Blood Management

Blood transfusion is a critical and life-saving facet of the care for cardiothoracic surgery patients. Inherent to the transfusing of blood is the understanding of the preservation of blood as..

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Risk factors for acute kidney injury and mortality in high risk patients undergoing cardiac surgery

Abstract Background Acute Kidney Injury (AKI) represents a clinical condition with poor prognosis. The incidence of AKI in hospitalized patients was about 22–57%. Patients undergoing cardiac surgery (CS) are particularly..

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Improved creatinine-based early detection of acute kidney injury after cardiac surgery

Abstract   OBJECTIVES This study aims to improve early detection of cardiac surgery-associated acute kidney injury (CSA-AKI) compared to classical clinical scores. METHODS Data from 7633 patients who underwent cardiac..

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Association of Plasma Fibrinogen and Thromboelastography With Blood Loss in Complex Cardiac Surgery

Abstract Postoperative coagulopathic bleeding is common in cardiac surgery and is associated with increased morbidity and mortality. Ideally, real-time information on in-vivo coagulation should be available. However, up to now..

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Utility of gas inlet pressure monitoring in extracorporeal membrane oxygenation

Abstract Purpose: Purpose: Condensation that clogs the hollow fibers of the oxygenation and accumulation of plasma leaks reduces oxygenated lung capacity. In this study, artificial We evaluated whether monitoring changes..

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Serum metabolic profile of postoperative acute kidney injury following infant cardiac surgery with cardiopulmonary bypass

Abstract Background We sought to determine differences in the circulating metabolic profile of infants with or without acute kidney injury (AKI) following cardiothoracic surgery with cardiopulmonary bypass (CPB). Methods We..

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Importance of high-performing teams in the cardiovascular intensive care unit

Abstract The importance of teamwork in health care delivery and patient safety is increasingly being recognized and has benefitted substantially by adopting a human factors' perspective and approach. The scientific..

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Systemic Hypertension in Pediatric Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Systemic hypertension (HTN) is a recognized complication of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in children. We sought to determine the prevalence and associated features of HTN in a..

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Extracorporeal CO2 removal and renal replacement therapy in acute severe respiratory failure in COVID-19 pneumonia: Case report

Abstract The COVID-19 pandemic significates an enormous number of patients with pneumonia that get complicated with severe acute respiratory distress syndrome (ARDS), some of them with refractory hypercapnia and hypoxemia..

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Wide complex tachycardia: differentiating ventricular tachycardia from supraventricular tachycardia

Abstract A wide QRS complex tachycardia (WCT) is defined as a tachycardia with QRS duration of >120 ms. Distinguishing between the different potential causes of a WCT can have important..

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Intraoperative Urinary Biomarkers and Acute Kidney Injury After Cardiac Surgery

Abstract Objectives To evaluate the association of intraoperative urinary biomarker excretion during cardiac surgery and the subsequent development of acute kidney injury (AKI). Design Prospective, nonrandomized, observational study. Setting Single..

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Intraoperative Cell Saving: Is the Solution the Actual Problem?

Abstract Allogenic blood is a scarce, precious, and expensive resource that is not always available on demand. After termination of cardiopulmonary bypass, a large amount of residual pump blood remains..

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Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial

Abstract Purpose We compared a restrictive fluid management strategy to usual care among critically ill patients with acute kidney injury (AKI) who had received initial fluid resuscitation. Methods This multicenter..

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Myocardial Protection in Adult Cardiac Surgery With del Nido Versus Blood Cardioplegia: A Systematic Review and Meta-Analysis

Abstract Background  in adult cardiac surgery is commonly achieved with either multidose blood  or single-dose del Nido crystalloid cardioplegia. Aim The aim of this systematic review and meta-analysis was to compare..

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Identification of risk factors for renal failure after cardiac surgery by RFILE classification

Abstract Objective: Acute kidney injury (AKI) is a major complication after cardiovascular surgery. The unclear etiology of this highly complex event challenges definition, diagnosis and prediction of AKI, and hence..

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Long-Term Cognitive Outcomes and Sleep in Adults After Extracorporeal Life Support

Abstract Objectives: To assess differences in cognitive outcomes and sleep in adult survivors of critical illness, managed with venovenous extracorporeal membrane oxygenation as compared to conventional mechanical ventilation only. Design:..

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Antecedent ACE-inhibition, inflammatory response, and cardiac surgery associated acute kidney injury

Abstract Cardiopulmonary bypass (CPB) may trigger organs damage, including kidney injury, due to a massive cytokine release. In this observational, prospective study, we analyzed the possible impact of chronic treatment..

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Is there a renoprotective value to leukodepletion during heart valve surgery? A randomized controlled trial (ROLO)

Abstract Background Acute Kidney Injury (AKI) adversely affects outcomes after cardiac surgery. A major mediator of AKI is the activation of leukocytes through exposure to the cardiopulmonary bypass circuit. We..

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Basics of extra corporeal membrane oxygenation: a pediatric intensivist’s perspective

Abstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external..

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Prognostic Utility of KDIGO Urine Output Criteria After Cardiac Surgery

Abstract Objectives Kidney Disease: Improving Global Outcomes (KDIGO) guidelines include assessment of creatinine and urine output to identify acute kidney injury (AKI). Whether urine output is an accurate indicator of..

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Predicting acute kidney injury following nonemergent cardiac surgery: A preoperative scorecard

Abstract Objective To determine the predictors of postoperative acute kidney injury (AKI) following nonemergent cardiac surgery among patients with variable preoperative estimated glomerular filtration rate (eGFR) levels. Methods A retrospective..

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Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks

Summary The COVID-19 pandemic strained health-care systems throughout the world. For some, available medical resources could not meet the increased demand and rationing was ultimately required. Hospitals and governments often..

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Hydroxyethyl starch and acute kidney injury in high-risk patients undergoing cardiac surgery: A prospective multicenter study

Abstract Background  (HES) solutions increase the risk of  (AKI) in critically ill patients admitted to intensive care unit (ICU) for medical indications. We conducted a cohort study to evaluate the renal..

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Management of Neonates With Tetralogy of Fallot

  Study Questions: What are the differences in outcomes between a strategy of staged repair (SR) (initial palliation [IP] and subsequent complete repair [CR]) as compared with primary repair (PR)..

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Feasibility of Healthcare Providers’ Autonomic Activation Recognition in Real-Life Cardiac Surgery Using Noninvasive Sensors

Abstract Cardiac surgery is one of the most complex specialties in medicine, akin to a complex sociotechnical system. Patient outcomes are vulnerable to surgical flow disruptions (SFDs), a source of..

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Cardiopulmonary bypass preparation is mandatory in cardiac exploration for blunt cardiac injury patients

Abstract Treating cardiac injuries following blunt trauma to the chest requires thorough examination, accurate diagnosis, and therapeutic plan. We present two cases; pulmonary vein rupture and left atrial appendage laceration,..

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The impact of minimal invasive extracorporeal circulation on postoperative kidney function

Abstract Introduction: Acute kidney injury following cardiac surgery is a frequent complication associated with increased mortality and morbidity. Minimal invasive extracorporeal circulation is suggested to preserve postoperative renal function. The..

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Unconscious (Implicit) Bias

Abstract Recognition, acknowledgment, and acceptance of biases in a nonjudgmental manner is key to advancing knowledge and avoiding biased behaviors. Unconscious biases do not mean people are bad, and they..

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Cardiac Biomarkers for Risk Stratification of Acute Kidney Injury After Pediatric Cardiac Surgery

Abstract Background Children undergoing a cardiac surgical procedure are at increased risk for acute kidney injury (AKI). Novel biomarkers are needed to improve risk stratification of AKI after cardiac surgery...

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