Yearly Archives: 2025

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Organ Donation

Organ Donation after 60 minutes of Complete Cardiac Death in Patient with Previous Cardiac Surgery Mitral Valve Replacement.   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center..

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Impact of Cannulation Strategy and Extracorporeal Blood Flow on Recirculation During Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Introduction Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is increasingly used in the treatment of severe respiratory failure. Despite a significant increase in the worldwide use of extracorporeal lung assist..

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Implementation of Bundled Interventions to Reduce Surgical Site Infections in Pediatric Patients Undergoing Cardiothoracic Surgery: A Quality Improvement Project

Abstract Pediatric patients undergoing cardiothoracic surgery are at increased risk for health care–associated infections, especially surgical site infections (SSIs). Delayed sternal closures are associated with prolonged lengths of stay and..

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Normothermic Crystalloid Polarizing Cardioplegia Improves Systolic and Diastolic Function in a Porcine Model of Cardiopulmonary Bypass

Abstract Background/Objectives: Previously, we showed that blood-based polarizing cardioplegia exerted beneficial cardioprotection during hypothermic ischemia; however, these positive effects of blood-based polarizing cardioplegia were reduced during normothermic ischemia compared to..

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The effects of changes in thrombocyte indices, on-on-pump time on prognosis in open heart surgery

Abstract Extracorporeal perfusion systems utilized in open-heart surgeries with cardiopulmonary bypass can affect multiple body systems. The primary adverse effects of Extracorporeal Perfusion Systems (EPS) on the hematological system include..

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Extracorporeal membrane oxygenation in pregnancy and the post-partum period: a systematic review and meta-analysis

Abstract Objective There is an increase in the application data of Extracorporeal Membrane Oxygenation (ECMO) in perinatal women, particularly since the outbreak of coronavirus disease 2019. Therefore, we reviewed publications..

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Developing active learning activities for didactic perfusion courses

Abstract Background In the world of academia, traditional lecturing has been the most common pedagogical approach for centuries. However, it can create an environment for students to be passive learners..

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Congenital cardiac surgical simulation: bridging global workforce gaps and optimizing outcomes

Abstract Reaching competency in congenital heart surgery (CHS) requires lengthy and rigorous training. Due to patient safety, time limitations, and procedural complexity, the intraoperative setting is not ideal for technical..

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Advances in understanding the effects of cardiopulmonary bypass on gut microbiota during cardiac surgery

Abstract Cardiopulmonary bypass (CPB) is an indispensable technique in cardiac surgery; however, its impact on gut microbiota and metabolites remains insufficiently studied. CPB may disrupt the intestinal mucosal barrier, altering..

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Effects of noradrenaline and phenylephrine on cerebral oxygen saturation during cardiopulmonary bypass in cardiac surgery

Abstract Cardiopulmonary bypass (CPB) in cardiac surgery is associated with a high risk of postoperative neurological complications. Perioperative use of vasopressors is common to counteract arterial hypotension in this setting...

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The influence of cardiopulmonary bypass residual volume processing technique on blood management in cardiac surgical patients

Abstract Background: Post-cardiopulmonary bypass (CPB) blood processing is an important component of blood management during cardiac surgery.    Purpose: The purpose of this study is to evaluate several methods of processing post-CPB..

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Acute aortic dissection during minimally invasive cardiac surgery: a case report

Abstract Background Management of acute aortic dissection (AAD) caused by retrograde perfusion through the femoral artery during minimally invasive cardiac surgery (MICS) remains controversial. We present a case of AAD..

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Direct Axillary Artery Cannulation as Standard Perfusion Strategy in Minimally Invasive Coronary Artery Bypass Grafting

Abstract Objective: Cardiopulmonary bypass (CPB) via the right axillary artery (RAA) has become an alternative perfusion strategy, especially in complex aortic procedures. This study delineates our technique and outcome with..

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Anti-platelet Factor 4 Antibody-Mediated Disorders: An Updated Narrative Review

Abstract Anti-platelet factor 4 (PF4) antibody-mediated disorders are a heterogeneous group of diseases characterized by the presence of highly pathogenic immunoglobulins G directed against PF4 and/or PF4/heparin complexes. These antibodies..

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Development of a health equity tool in resuscitation sciences and application to current research in extracorporeal cardiopulmonary resuscitation for cardiac…

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for adults with cardiac arrest (CA) refractory to Advanced Cardiovascular Life Support (ACLS). Concerns exist that adding ECPR could worsen health..

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Preoperative vascular dysfunction is associated with acute kidney injury after cardiac surgery

Abstract Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) results in poor prognosis. Several risk factors for CSA-AKI have been reported, including preoperative creatinine level, cardiopulmonary bypass time, and perioperative blood pressure..

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ECMO in the Cardiac Catheterization Lab—Patient Selection Is Key

Abstract The use of extracorporeal membrane oxygenation (ECMO) has emerged as a rescue intervention for hemodynamically unstable patients and prophylactic intraprocedural hemodynamic support in the cardiac catheterization laboratory. The prompt..

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The Renal Effect of 20% Human Albumin Solution Fluid Bolus Therapy in Patients After Cardiac Surgery. A Secondary Analysis of…

Abstract Objective To compare the effects of fluid bolus therapy (FBT) with 20% albumin to crystalloid FBT on the incidence of cardiac surgery–associated acute kidney injury (CSA-AKI) and its severity..

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Quality of registration and adherence to guidelines for blood management in CABG surgeries: a case study

Abstract In many hospitals, patients undergoing cardiac surgery receive a higher amount of blood products transfusions compared to other disciplines. Blood transfusion comes with risks and drawbacks, such as increased..

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Cytokine Hemoadsorption versus Standard Care in Cardiac Surgery Using the Oxiris® Membrane: the OXICARD single center randomized trial

Abstract Background:  Cardiac surgery can lead to dysregulation with a pro-inflammatory state, resulting in adverse outcomes. Hemadsorption using the AN69 membrane (Oxiris membrane) has the properties to chelate inflammatory cytokines...

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Advancing extracorporeal carbon dioxide removal technology: bridging basic science and clinical practice

Abstract Recently, advancements in extracorporeal carbon dioxide removal (ECCO2R) technology have markedly enhanced its clinical applicability and efficacy for managing severe respiratory conditions. This review highlights critical innovations in ECCO2R,..

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The superiority of veno-arterial over veno-venous extracorporeal membrane oxygenation for operative support of lung transplantation

Abstract Background Veno-arterial (V-A) and veno-venous (V-V) extracorporeal membrane oxygenation (ECMO) are crucial support modalities during lung transplantation, yet their comparative effectiveness remains unclear. Methods We conducted an 8-year retrospective..

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Can clinical guidelines reduce variation in transfusion practice? A pre–post study of blood transfusions during cardiac surgery

Abstract Background and Objectives Previously published studies have consistently identified significant variation in red blood cell (RBC) transfusions during cardiac surgery. Clinical guidelines can be effective at improving the average..

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Best Practices for Vessel Management in Pediatric Extracorporeal Membrane Oxygenation Cannulation, Decannulation, and Follow-up: A Narrative Review

Abstract Extracorporeal membrane oxygenation (ECMO) to support neonates and children with cardiopulmonary failure was first described in the 1970s, since which time its use has expanded to an increasingly complex..

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Moving towards a core measures set for patient safety in perioperative care: An e-Delphi consensus study

Abstract A Core Measures Set (CMS) is an agreed standardized group of measures that should be assessed and reported in research for a specific condition or clinical area. This study..

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Treatment of Cardiogenic Shock: Inotropes, Vasopressors and Machines

Abstract Cardiogenic shock (CS) is associated with significant mortality. Advances in pharmacological therapies and mechanical circulatory support (MCS) devices have markedly improved the therapeutic approach to CS, though treatment efficacy..

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Intraoperative iatrogenic type B aortic dissection. Temporary perfusion pause, immediate restoration and final solution

Abstract We present the case of a 74-year-old female patient with a 50 mm ascending aortic aneurysm who underwent ascending aorta replacement. During routine open heart surgery, suboptimal flow in..

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Combining cardiac and renal biomarkers to establish a clinical early prediction model for cardiac surgery-associated acute kidney injury: a prospective…

Abstract Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a prevalent complication with poor outcomes, and its early prediction remains a challenging task. Currently available biomarkers for acute kidney injury (AKI)..

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A Novel Valveless Pulsatile Flow Pump for Extracorporeal Blood Circulation

Abstract Extracorporeal Membrane Oxygenation (ECMO) is a modality of extracorporeal life support which allows temporary support in cases of cardiopulmonary failure and cardiogenic shock. This study presents a valveless pump..

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CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach

Abstract Objective This study sought to evaluate the value of a CO2 field-flooding device in cardiopulmonary bypass (CPB) surgical procedures for congenital heart disease (CHD) performed via a right-side small incision..

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