Yearly Archives: 2025

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Adaptation mechanisms of cardiomyocytes isolated from patients with Tetralogy of Fallot to hypoxic conditions

Abstract Introduction Congenital cardiac defects disrupt circulation and oxygenation due to structural changes in the heart. Tetralogy of Fallot is the most common cyanotic congenital heart disease, accounting for 5..

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Risk assessment of temporary pacing for cardiac arrest after cardiopulmonary bypass-assisted cardiovascular surgery: A case-control study

Abstract Objective Cardiac arrest happens in 0.7%-5.2% patients after cardiovascular surgery, and cases with asystole or severe bradycardia need timely temporary pacing. However, routine temporary pacing wire insertion in cardiopulmonary..

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Prophylactic corticosteroids in neonatal cardiac surgeries using cardiopulmonary bypass: a systematic review and meta-analysis

Abstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size..

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Integrated pipeline for minimally invasive extracorporeal circulation: A basic experimental study

Abstract Objective This study aims to evaluate the operational feasibility of a self-designed minimally invasive extracorporeal circulation integrated circuit (miECC) type IV system and to assess the effectiveness of the..

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Investigation of Inflammatory Reduction During Extracorporeal Membrane Oxygenation Using a Novel Cytokine Adsorption Column: A Rat Model Study

Abstract Background: Cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) are widely used. Previous methods to reduce inflammation have shown inconsistent results. We developed a cytokine adsorption column using polymethyl methacrylate..

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Association between venous to arterial carbon dioxide tension gap and clinical outcome in cardiac surgery patients: A systematic review and…

Abstract Background Cardiac surgery is associated with increased risk of major adverse outcomes. Venous to arterial carbon dioxide tension gap (Pv-aCO2 gap) showed significant prognostic value of non-cardiac surgery, while their..

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Managing Coagulation Using the Sonoclot Analyzer in Patients With Disseminated Intravascular Coagulation

Abstract Background Evidence for the effectiveness of the Sonoclot analyzer in improving clinical outcomes in disseminated intravascular coagulation (DIC) is lacking. Objective To evaluate the effectiveness of an algorithm based..

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Worldwide application and valuation of extracorporeal membrane oxygenation support during the COVID-19 pandemic (WAVES)

Abstract Objective The outcomes of COVID-19 patients on venovenous extracorporeal membrane oxygenation (VV-ECMO) varied. We aim to investigate the variability concerning location and timeframe. We conducted a retrospective analysis of..

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Intraoperative Autologous Blood Transfusion in Aortic Surgery

Abstract Aortic surgeries are associated with intraoperative blood loss, often requiring allogeneic blood transfusion. Therefore, blood must be viewed as a scarce resource that carries risks and benefits. Many preoperative..

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Experiences With International Transports on Extracorporeal Membrane Oxygenation: Special Considerations and Challenges

Abstract Extracorporeal membrane oxygenation (ECMO) is a crucial support for patients with severe cardiac or respiratory failure, but its availability is limited, often requiring patient transport to specialized centers. Only..

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Does the venous cannulation method affect gaseous embolic load to the patient during extracorporeal circulation?

Abstract Introduction Cardiopulmonary bypass (CPB) is essential for cardiac surgery but poses risks, including gaseous micro emboli (GME). While the incidence of stroke—a common clinical consequence of embolism—ranges from 1-5%..

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Aortic valve with conduit enhanced autologous pulmonary valve

Changing aortic valve with conduit enhanced autologous pulmonary valve in a modified Ross operation with minimally invasive technique.  [playlist ids="49781"]   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research..

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Impact of ICU-Based Extracorporeal Membrane Oxygenation and Blood Purification Therapy on the Time Required for Early Rehabilitation

Abstract Background Early rehabilitation in an intensive care unit (ICU) can shorten the ICU stay and reduce the associated risks and costs. However, mobilization has been shown to be slower..

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Ascorbic acid and microcirculation in cardiothoracic surgery: a pilot feasibility trial and matched cohort study

Abstract Background Ascorbic acid is an essential cofactor of catecholamine synthesis that increases capillary bed density and improves microcirculation perfusion. We hypothesized early ascorbic acid administration in cardiothoracic surgery would..

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High-Granularity Machine Learning Prediction of Acute Brain Injury in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation

Abstract Acute brain injury (ABI) is prevalent among patients undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) and significantly impact recovery. Early prediction of ABI could enable timely interventions to prevent adverse..

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Device profile of the integrated VitalFlow ECMO system

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a life support system composed of a pump, an oxygenator, hemocompatible component coating, and integrated monitoring. ECMO systems have evolved greatly since the..

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Evaluation of a low-cost portable NIRS device for monitoring muscle ischemia

Abstract The main objective of this study is to evaluate the low-cost, open-source HEGduino device as a tissue oximetry monitor to advance the research of somatic NIRS monitoring. Specifically, this..

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A rule-based clinical decision support system for detection of acute kidney injury after pediatric cardiac surgery

Abstract Background Acute kidney injury (AKI) is common in children with congenital heart disease following open-heart surgery with cardiopulmonary bypass (CPB). Early AKI detection in critically ill children requires clinician..

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Veno-venous extracorporeal membrane oxygenation exacerbates lung ischaemia–reperfusion injury in a rat model

Abstract OBJECTIVES Although lung transplantation has experienced great development in the past decades, the survival rate remains low, and lung ischaemia–reperfusion injury during transplantation is a major cause of primary..

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Mechanical circulatory support in cardiogenic shock: translating trial evidence into real-world practice

Abstract While iterative developments have improved outcomes of patients with myocardial infarction, mortality in patients with acute myocardial infarction cardiogenic shock (AMI-CS) remains stubbornly high. Several promising treatments have ultimately..

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Patient Characteristics and Extracorporeal Membrane Oxygenation Outcomes at Nelson Mandela Children’s Hospital: A South African Experience

Abstract This study aimed to describe patient characteristics, mortality, and morbidity outcomes in children at a South African extracorporeal membrane oxygenation (ECMO) center. Fifty-seven patients required ECMO from 2018 to..

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Microplastic in perfusion: the hidden risk and how to address it

Abstract The paper published in this issue of the ICVTS by Green and colleagues [] from the University of Hull in the UK addresses an often underestimated yet increasingly recognized issue in..

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Impact of frailty on outcomes after cardiac surgery

Abstract Objective The study objective was to evaluate whether increasing , as measured by the Clinical Frailty Scale, was associated with an increased risk of hospital mortality for patients undergoing cardiac..

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Protocol for the development of NHMRC-endorsed guidelines for extracorporeal membrane oxygenation using GRADE methodology

Abstract Introduction The last 15 years have seen a rapid expansion in the use of extracorporeal life support. ECMO has evolved from a rescue treatment available in a few expert..

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No benefit of adding mannitol to cardiopulmonary bypass priming solution assessing cystatin C. A randomized clinical trial

Abstract Introduction There is no recommendation regarding the optimal prime solution for the cardiopulmonary bypass circuit in adult cardiac surgery. Despite the lack of scientific evidence, mannitol has frequently been..

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Troubleshooting for the Empowered ECMO Nurse

Abstract An Introduction to ECMO Troubleshooting Like other ECMO nurses, I will never forget the first time I had to troubleshoot an  circuit. My patient had returned to the intensive care..

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Association between venous to arterial carbon dioxide tension gap and clinical outcome in cardiac surgery patients: A systematic review and…

Abstract Background Cardiac surgery is associated with increased risk of major adverse outcomes. Venous to arterial carbon dioxide tension gap (Pv-aCO2 gap) showed significant prognostic value of non-cardiac surgery, while their..

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Comparison of outcomes between axillary and femoral artery cannulation for type A aortic dissection surgery

Abstract Objective To compare the application and outcomes of femoral versus axillary arterial cannulation in adult patients undergoing surgery for type A aortic dissection. Methods We conducted a retrospective review..

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Postoperative hemoglobin changes following ultrafiltration in cardiac patients

Abstract Introduction This retrospective study investigated the relationship between differing thresholds of Conventional Ultrafiltration (CUF) and postoperative hemoglobin (HGB) in cardiac surgery cases involving cardiopulmonary bypass. Methods The study utilized..

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Utilization and outcomes of nonintubated extracorporeal membrane oxygenation as a bridge to lung transplant

Abstract Background Nonintubated extracorporeal membrane oxygenation (ECMO) has been increasingly utilized for patients with severe respiratory failure. Since data on its use as a bridge to lung transplant remain limited,..

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