Yearly Archives: 2025

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We’re no longer flying blind—resuscitation in the ECPR era

Abstract As extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly utilized for refractory cardiac arrest in adults, we learn significantly more about resuscitation in ways that were not applicable, or even available..

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Prognostic Value of Perioperative Near-Infrared Spectroscopy Monitoring for Postoperative Acute Kidney Injury in Pediatric Cardiac Surgery: A Systematic Review

Abstract Introduction Postoperative acute kidney injury (AKI) is a common postoperative complication in cardiac surgery, with varying reported incidences and prognostic factors. Renal hypoperfusion is believed to be a key..

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Numerical Investigation of Gas Exchange Processes in Hollow-Fiber Membrane Bundles

Abstract The geometric configuration of fiber bundles plays a critical role in gas transfer for membrane oxygenators; however, experimentally studying its impact on gas transfer distribution is challenging. This study..

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Microplastic in perfusion: the hidden risk and how to address it

Abstract The paper published in this issue of the ICVTS by Green and colleagues [] from the University of Hull in the UK addresses an often underestimated yet increasingly recognized issue in..

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Validation and optimization of a blood transfusion prediction model for low transfusion rate adult cardiac surgery

Abstract Introduction Blood transfusion is associated with adverse events and should be prevented. Preoperative identification of patients at risk is necessary and makes subsequent preventive intervention possible. Many risk models..

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Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review

Abstract Background The human bioaccumulation of micro- and nano-plastics (MNPs) is increasingly being recognised in the aetiology and pathophysiology of human disease. Objective This systematic scoping review aims to provide..

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Development, validation, and clinical evaluation of a machine-learning based model for diagnosing early infection after cardiovascular surgery (DEICS): a multi-center…

Abstract Background:  This study addresses the critical need for timely and accurate diagnosis of early postoperative infection (EPI) following cardiac surgery. EPI significantly impacts patient outcomes and healthcare costs, making..

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Exploring the influence of extra-corporeal membrane oxygenation (ECMO) support on neurodevelopmental outcomes in paediatric cardiac patients: a systematic review

Abstract Background:Mechanical circulatory support, and specifically extra-corporeal membrane oxygenation, plays a critical role in managing paediatric cardiac patients with severe heart failure. Whilst these technologies are vital for bridging patients..

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A novel blood volume monitoring approach in a venous reservoir using a laser displacement sensor for blood surface distance measurement

Abstract A venous reservoir (VR) is crucial for safe blood volume regulation during cardiopulmonary bypass (CPB) procedures. Currently, blood volume measurement in VRs relies heavily on visual inspection, which limits..

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Nutrition Provision in Pediatric Extracorporeal Membrane Oxygenation: Evidence, Challenges, and Clinical Considerations

Abstract Background/Objectives: Nutritional support is a critical yet challenging aspect of care for pediatric patients requiring extracorporeal membrane oxygenation (ECMO). Malnutrition is prevalent in this population and is associated with..

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A Novel Approach to Sequential Organ Failure Assessment (SOFA) Using Near-Infrared Spectroscopy in Extracorporeal Membrane Oxygenation (ECMO) Patients

Abstract Extracorporeal membrane oxygenation (ECMO) is a medical device that provides temporary external circulation and respiratory support during heart-lung procedures, substituting for heart and lung function to alleviate their burden..

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ECPella 5+ in Patients With Cardiogenic Shock: Potential for Improved Outcomes

Abstract The use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for temporary mechanical circulatory support (MCS) is a common treatment in patients with cardiogenic shock (CS) but is associated with high..

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Intraoperative Assessment of Cerebral Autoregulation With Cerebral Oximetry Index in Neonates Undergoing Cardiac Surgery: A Pilot Study

Abstract Abstract Objective To investigate cerebral autoregulation impairment during neonatal cardiac surgery. Design A retrospective observational study. Setting Single-center, university teaching children’s hospital. Participants Neonates undergoing surgery for critical congenital..

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A Year of Advances in Cardiac Surgery, Transplantation, and Anesthetic Management

Introduction Superlatives and acronyms abound in this year’s edition of annual noteworthy literature for Seminars in Cardiothoracic and Vascular Anesthesia. By the numbers, over 22 000 publications from 2024 were screened, and approximately..

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Reducing Greenhouse Gas Emissions and Modifying Nitrous Oxide Delivery at Stanford: Observational, Pilot Intervention Study

Abstract Background: Inhalational anesthetic agents are a major source of potent greenhouse gases in the medical sector, and reducing their emissions is a readily addressable goal. Nitrous oxide (N2O) has..

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PEGylation of Propofol Reduces Its Adsorption to Extracorporeal Membrane Oxygenator (ECMO) Components

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving cardiopulmonary bypass technology for critically ill patients. Patients treated with ECMO receive multiple drugs to treat critical illnesses, prevent infections, and maintain..

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Cardiac Arrest: An Adult eCPR Simulation Case

Abstract Introduction: Extracorporeal cardiopulmonary resuscitation (eCPR) has demonstrated patient outcome-driven benefits for those with out-of-hospital cardiac arrest in refractory ventricular fibrillation/pulseless ventricular tachycardia but remains an infrequent procedure requiring hands-on training...

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Intranasal insulin enhances postoperative sleep quality and delirium in middle-aged cardiac surgery patients: A randomized controlled trial

Abstract Background Postoperative delirium (POD) remains a significant complication following cardiopulmonary bypass (CPB) surgery, particularly in middle-aged patients who constitute the majority of this surgical population. While intranasal insulin (INI)..

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Perioperative management of adult patients undergoing coronary artery bypass grafting and valve surgery: a literature review

Abstract Purpose of review  Coronary artery bypass grafting, revascularization by percutaneous coronary intervention, and heart valve surgery are crucial therapeutic interventions for patients with various cardiovascular diseases. The objective of..

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ECPR in the Emergency Department

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) is a time-critical, resource-intensive intervention used in select cases of refractory cardiac arrest. Its success depends on rapid initiation, streamlined workflows, and coordination across multidisciplinary..

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Survival Prediction for Non–Asphyxia-Related Hypothermic Cardiac Arrest Patients After Extracorporeal Rewarming: Development of the HELP Score

Abstract The aim of this study was to develop a scoring tool to estimate the probability of survival following extracorporeal rewarming in patients suffering hypothermic cardiac arrest. This is a..

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Prognostic Role of Pre-Cannulation Lactate in Trauma Patients Undergoing Venovenous Extracorporeal Membrane Oxygenation

Abstract Although venovenous (VV) extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for trauma patients with severe respiratory failure, its mortality rate is 27%, and optimal metabolic markers for its..

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Alteration in Indole Metabolites After Cardiopulmonary Bypass Surgery in Neonates and Infants

Abstract IMPORTANCE:  Cardiopulmonary bypass (CPB) surgery is associated with changes in the intestinal microbiome. Metabolism of tryptophan into the indole pathway is entirely facilitated by the intestinal microbiome, and indole..

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Using high-frequency oscillation to detect acute brain injury in extracorporeal membrane oxygenation supported patients

Abstract Objective This study aims to utilize HFO analysis to enhance existing SSEP modality and develop it as a bedside diagnostic tool for acute brain injury (ABI) detection in Extracorporeal..

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Comparative analysis of routine clinical debriefings and incident reports: insights for patient safety and teamwork enhancement

Abstract Background Routine clinical debriefings (RCDs) have been shown to improve communication, team reflexivity, and safety in clinical settings. When combined with incident reports (IRs), RCDs offer a potential tool..

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Functional outcomes among the survivors of veno-venous extracorporeal membrane oxygenation during the COVID-19 pandemic: a historical cohort study

Abstract Purpose Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is increasingly being used in patients with respiratory failure. The goal of this study was to characterize postdischarge psychological and functional outcomes of..

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Hemolysis in a Novel Centrifugal Blood Pump With Low Priming Volume: In Vitro Comparative Study Using Human Blood and Numerical…

Abstract Extracorporeal circulation (ECC) procedures, including extracorporeal membrane oxygenation (ECMO), provide essential support for critically ill patients, but complications such as hemolysis and thromboembolic events remain significant concerns. This study..

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A Machine Learning-Based Clustering Analysis to Explore Bisphenol A and Phthalate Exposure from Medical Devices in Infants with Congenital Heart…

Abstract Background: Plastic-containing medical devices are commonly used in critical care units and other patient care settings. Patients are often exposed to xenobiotic agents that are leached out from plastic-containing..

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Extracorporeal Membrane Oxygenation: Consideration of Human Factors in Intensive Care Patients

Abstract Background Approximately 6000 intensive care units (ICUs) in the United States maintain extracorporeal membrane oxygenation (ECMO) programs.1 Patients who require ECMO are among the most critically ill in the ICU...

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