Monthly Archives: agosto 2025

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3D Membrane Microstructures for Increased Efficiency in Blood-Gas Transfer

Abstract Treating severe lung diseases with extracorporeal membrane oxygenation (ECMO) is often accompanied by serious complications, restricting applicability and adversely affecting outcomes. Membrane oxygenators, based on hollow fiber membranes (HFM),..

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Preparation of a cardiopulmonary bypass priming solution for infants and neonates – effect of pre-bypass ultrafiltration on heparinization

Abstract Introduction Heparin is usually added to infant cardiopulmonary bypass circuit primes. Ultrafiltration is often used to minimise prime volume before commencing bypass. The extent of heparin removal from bypass..

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Multidisciplinary Applications of VR & AR Technologies in Professional Training: A Multi-centre Simulation Study

Abstract This study focuses on the impact of virtual reality (VR) technologies on educational processes and professional training, particularly in the fields of medicine, aviation, and the arts. The purpose..

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Multisite Venovenous Extracorporeal Membrane Oxygenation in Pediatric Patients Under 15 kg: Three-Center, Analysis of Surgical Versus Percutaneous Approach and Thrombosis…

Abstract Objectives:  An increasing number of pediatric centers use the femoral vein in neonates and smaller children to provide venovenous multisite (VVMS) extracorporeal membrane oxygenation (ECMO), but there are no..

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Acute Brain Injury in COVID-19 Versus Influenza A Patients on Venovenous Extracorporeal Membrane Oxygenation: A Propensity Score Matching Analysis of…

Abstract Objectives:  Limited data exist on outcomes in COVID-19- vs. influenza A (H1N1)-associated acute respiratory distress syndrome (ARDS) patients when supported on venovenous extracorporeal membrane oxygenation (ECMO). We aimed to..

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Network Meta-Analysis of Axillary, Femoral, and Central Arterial Cannulation in Minimally Invasive Cardiac Surgery

Abstract The optimal arterial cannulation site in minimally invasive cardiac surgery (MICS) remains debated. While axillary, femoral, and central approaches each offer distinct advantages, no prior network meta-analysis has compared..

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The Global Outbreak of M. chimaera Infection Following Cardiac Surgery: Another Piece of the Puzzle

Abstract Invasive cases of Mycobacterium chimaera have been found in Europe, and beyond, and have been associated with the use of heater–cooler units necessary to regulate the temperature of blood in extracorporeal..

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A nitric oxide-releasing organic selenium-grafted phosphorylcholine coating for thrombosis and inflammation prevention in extracorporeal membrane oxygenation

Abstract Thrombosis and inflammation represent major challenges limiting the functionality of asymmetric poly(4-methyl-1-pentene) (PMP) hollow fiber membranes in extracorporeal membrane oxygenation (ECMO) systems. Moreover, the interplay between these two pathological..

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Acquired factor XIII deficiency in adult patients during ECMO: a prospective observational study

Abstract Data on factor XIII (FXIII) activity in patients on extracorporeal membrane oxygenation (ECMO) are scarce. In this prospective, observational, single-centre study, we determined the rate of acquired FXIII deficiency..

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Heart support crossroads: aortic Impella 5.5 implantation compared to conventional axillary approach in combined use of extracorporeal membrane oxygenation and…

Abstract Background: Postcardiotomy shock, often necessitates advanced mechanical circulatory support. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and the Impella 5.5 device are crucial for hemodynamic stabilization. This study evaluates the efficacy and..

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Ventricular Assist Devices and Other Mechanical Circulatory Support Devices: Types, Complications, and Updates

Abstract Mechanical circulatory support devices (MCSDs) have revolutionized the management of advanced heart failure and critical cardiopulmonary conditions. These devices, categorized into temporary and long-term systems, provide crucial circulatory and..

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Hydrogen’s Feasibility and Safety as a Therapy in Extracorporeal Cardiopulmonary Resuscitation (Hydrogen-FAST): study protocol for a trial of inhaled hydrogen…

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival for patients experiencing refractory cardiac arrest but is often associated with severe ischemia-reperfusion injury (IRI). Hydrogen gas (H2) has demonstrated promising preclinical..

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Extracorporeal membrane oxygenation in obstetrical patients: a meta-analysis

Abstract Critically acute and ill and Obstetrical patients constitute a unique clinical population with a high mortality rate. Extracorporeal membrane oxygenation (ECMO) is gradually being used in obstetrical acute and..

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Numerical Analyses of Blood Pumps Under Realistic Operating Conditions

Abstract Computational fluid dynamics (CFD) assessments in blood pumps (BPs) typically rely on constant boundary conditions, despite the dynamic nature of the cardiovascular system. Consensus on CFD methodologies for simulating..

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Surgical Site Infection in Pediatric Patients Undergoing Cardiac Surgery with Delayed Sternal Closure: Experience from a Center in Chile (2015–2020)

Abstract Delayed sternal closure (DSC) is a technique used in complex cardiac surgery (CCS) and is associated with an increased risk of surgical site infection (SSI). SSI increases hospital stay..

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A scoping review: Point-of-care ultrasound (POCUS) use in paediatric ECMO

Abstract Objective This scoping review aimed to examine current literature on the use of point-of-care ultrasound (POCUS) in paediatric patients supported by extracorporeal membrane oxygenation (ECMO). It assessed existing evidence,..

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Renal Angina Index as a Predictor of Renal Injury Progression in Patients on Extracorporeal Membrane Oxygenation Support: The DREAMS Study

Abstract This retrospective cohort study evaluates the validity of the Renal Angina Index (RAI) in predicting acute kidney injury (AKI) in 272 patients receiving extracorporeal membrane oxygenation (ECMO) support. The..

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Strategies to predict and decrease flow rate pulsation in a rotary peristaltic pump with novel tube design

Abstract Peristaltic pumps are commonly used in medical applications like cardiopulmonary bypass and drug infusion due to their minimal contact with bio-fluids and precise flow control. However, these pumps generate..

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Optimization of carbon dioxide insufflation strategies in minimally invasive cardiac surgery: the efficacy of continuous insufflation protocols with left ventricular…

Abstract Objectives Although CO₂ insufflation play an established role in open-heart surgery, its optimal application in minimally invasive cardiac procedures remains unclear. This study systematically compared continuous versus single CO₂..

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Hemodynamic considerations of ipsilateral versus contralateral cannulation with venoarterial extracorporeal membrane oxygenation

Abstract Objective Patients on venoarterial extracorporeal membrane oxygenation undergoing ipsilateral cannulation may develop distal limb ischemia. We postulate 2 clinical questions: (1) Would contralateral cannulation have a lower distal limb..

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Impact of Intraoperative Hyperoxia Versus Normoxia on Mortality and Organ Injury in Cardiac Surgery: A Systematic Review and Meta-analysis of…

Abstract Objective To compare mortality and organ injury associated with intraoperative hyperoxia and normoxia in cardiac surgery patients. Design Systematic review and meta-analysis of randomized clinical trials (RCTs). Setting Tertiary..

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Flow patterns through side holes of venous cannula in mock circulation loop

Abstract Cannulae with multi-staged side holes (SHs) for venous drainage are widely used for performing extracorporeal circulation. Various types of catheters are used worldwide; however, data on the flow performance..

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Preoperative Extracorporeal Membrane Oxygenation as a Bridge to Cardiac Surgery: Outcomes and Challenges

Abstract Background Outcomes of postcardiotomy extracorporeal membrane oxygenation (ECMO) are well studied, but preoperative ECMO bridging is less studied. This single-center review evaluates outcomes of patients supported with ECMO as..

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Peri-operative Immunoglobulin Dynamics and Infection Risk in Infants Undergoing Congenital Heart Surgery: A Prospective Observational Cohort

Abstract Background:  Infants with congenital heart disease (CHD) frequently undergo surgery during their first year of life. Infants undergoing CHD surgery experience systemic inflammation and haemodilution that can deplete circulating..

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Implantation of integrated magnetically levitated biventricular assist devices (DuoCor) – a single-center clinical experience

Abstract Background:  End-stage heart failure remains a major global health challenge with high mortality. While heart transplantation is the gold-standard treatment, the scarcity of donor hearts necessitates alternative therapies. Left..

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Plasma fibrinogen level and severe bleeding in cardiac surgery: an observational post hoc study of the ALBICS trial

Abstract Purpose Fibrinogen is widely used in cardiac surgery. Still, reported associations between plasma fibrinogen level and chest tube drainage are weak. The results of trials on fibrinogen supplementation are..

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Stroke after aortic arch surgery with short circulatory arrest times: The role of cerebral perfusion strategies

Abstract Background Neuroprotection during aortic arch surgery often involves hypothermia and the use of adjunctive cerebral perfusion. While antegrade cerebral perfusion (ACP) is favored for extended hypothermic circulatory arrest (HCA),..

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Feasibility of Veno-Venous Extracorporeal Membrane Oxygenation Cannulation via the Neck in a Patient With Spinal Cord Injury Wearing a Halo…

Abstract To our knowledge, no previous reports have described the use of veno-venous extracorporeal membrane oxygenation (V-V ECMO) in patients wearing a halo vest. We present a case in which..

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Cardiac index, SvO2 or pCO2 gap may determine benefit from ECMO in cardiogenic shock: post-hoc analysis of the multicenter, randomized…

Abstract Background Immediate initiation of extracorporeal membrane oxygenation (ECMO) has not demonstrated benefit in individuals diagnosed with cardiogenic shock based on the presence of hypotension. The relationship between other hemodynamic..

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Temporary Occlusion of Patent Ductus Arteriosus in Adult during Cardiac Surgery

Abstract INTRODUCTION: Patent ductus arteriosus in adults is rare, and is commonly recommended to be closed due to the possibility of cardiac complications. Patent ductus arteriosus closure has been often performed..

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