Abstract Critically ill patients rescued with extracorporeal membrane oxygenation (ECMO) are at risk for devastating complications, including stroke and intracerebral hemorrhage (ICH). Despite an appreciation of some clinical risk factors, we..
Read MoreAbstract Purpose of review The process of weaning from venovenous extracorporeal membrane oxygenation (V-V ECMO) is a critical step in the recovery of patients with severe acute respiratory distress syndrome..
Read MoreAbstract Objectives Acute kidney injury (AKI) occurs in 19–42% of patients with cardiac surgery under cardiopulmonary bypass (CPB). Clarifying their landscape of immune cells may help discover the mechanisms and..
Read MoreAbstract Background The Association between hyperoxia and mortality in patients receiving extracorporeal membrane oxygenation (ECMO) remains controversial. This study aimed to systematically evaluate the impact of arterial hyperoxia on mortality..
Read MoreAbstract The anticoagulant proteins antithrombin, protein C, protein S, and tissue factor pathway inhibitor are physiological regulators of the blood coagulation pathway and have complex roles in causing or modifying..
Read MoreAbstract Background Platelet transfusions are frequently given to preterm neonates. However, observational and randomized studies have reported higher morbidity and mortality associated with increased numbers of transfusions. We hypothesized that..
Read MoreAbstract Acute type A aortic dissection is a life-threatening condition requiring immediate surgical intervention. However, the optimal arterial cannulation site for cardiopulmonary bypass during surgery remains a subject of debate...
Read MoreComparing fluid dynamics of newborn and adult centrifugal pumps in cardiopulmonary bypass procedures
Abstract Background Cardiopulmonary bypass (CPB) plays a crucial role in cardiac surgery, with the pump being a key component affecting both hemolysis and thrombosis. Centrifugal levitating pumps (CP) have demonstrated..
Read MoreAbstract Background Cannulation for peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) can lead to severe local complications. This study evaluated site-specific complications between percutaneous and surgical cannulation techniques for femoro-femoral..
Read MoreAbstract Purpose Prolonged ECMO has become more common during the COVID-19 pandemic but is associated with high resource utilization and poor outcomes. This study aimed to identify predictors of prolonged..
Read MoreAbstract OBJECTIVES: Acute kidney injury (AKI) occurs frequently in ICUs and is associated with poor outcomes. However, little is known about AKI in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) for..
Read MoreAbstract Objectives To describe the incidence and survival of extracorporeal membrane oxygenation (ECMO) deployment in the operating room (OR) for failure to wean from cardiopulmonary bypass (CPB) after surgery for..
Read MoreAbstract Hemodynamic instability during cardiac surgery, particularly procedures requiring cardiopulmonary bypass, increases the risk of mortality and adverse events. Conventional anesthetics such as propofol and etomidate have limitations in maintaining..
Read MoreAbstract Real-time, quantitative biosensing within extracorporeal perfusion (ECP) and extracorporeal membrane oxygenation (ECMO) systems is key to advancing this life-support technology beyond the hospital setting to emergency care. Measuring and..
Read MoreAbstract Objectives: In neonates, the carotid artery can be ligated or reconstructed at the time of decannulation from venoarterial extracorporeal membrane oxygenation (VA-ECMO). However, there is a paucity of data..
Read MoreAbstract Purpose of review Acute kidney injury (AKI) is common in critically ill patients, especially among those with severe and advanced organ failure. The use of extracorporeal support (ECS) is..
Read MoreAbstract Objective Extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) are often used together to treat critically ill patients. This systematic review aims to assess mortality and renal..
Read MoreAbstract Objective To systematically evaluate the influence of cannula direction in central venoarterial extracorporeal membrane oxygenation (CVA ECMO) on aortic hemodynamics and oxygen transport through a multiparametric comparative analysis under..
Read MoreAbstract Background Veno-pulmonary artery extracorporeal membrane oxygenation (V-P ECMO) is a configuration of extracorporeal life support (ECLS) for patients with isolated or predominantly right ventricular (RV) failure and inadequate gas..
Read MoreAbstract Background For decades, the intra-aortic balloon pump (IABP) has been a reliable and readily available pillar of therapy for cardiogenic shock (CS). However, no clinical markers have been validated..
Read MoreAbstract Background Laboratory research suggests that vasopressin restores systemic arterial pressure without significantly increasing pulmonary artery pressures, compared with norepinephrine. We therefore tested the hypotheses that treatment of intraoperative vasoplegia..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized in critical care globally to allow for adequate oxygenation in patients with cardiac and/or respiratory failure. Unfortunately, haemostatic complications – both..
Read MoreAbstract Background The Extracorporeal Life Support Organization recommends daily antithrombin monitoring and supplementation to achieve > 50%–80% activity during extracorporeal membrane oxygenation (ECMO). Evidence supporting this practice is uncertain, and whether..
Read MoreAbstract Background The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions in anaemic patients remains an active area of research. Blood is a limited resource, and there..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is now commonly used to manage refractory pediatric cardiac or respiratory failure. Traditionally, ECMO has been associated with high morbidity. However, despite advancements in ECMO..
Read MoreAbstract ECPR Efficacy and Use: Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival and neurologic outcomes in refractory out-of-hospital cardiac arrest, with global adoption and center availability expanding significantly.
Read MoreAbstract Purpose The benefits of adopting restrictive transfusion strategies, as opposed to a liberal approach, during extracorporeal membrane oxygenation (ECMO) remain unclear. This network meta-analysis aims to determine whether a..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) can cause blood water loss due to insensible perspiration via oxygenators and plasma leakage. The accurate quantification of water loss is crucial for maintaining..
Read MoreAbstract BACKGROUND Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at risk for peri-operative complications, often linked to endothelial dysfunction. The Endothelial Activation and Stress Index (EASIX) has shown..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (eCPR) is a highly resource-intensive procedure, and its cost-effectiveness remains a subject of debate []. Hospital-based eCPR for refractory out-of-hospital cardiac arrest has been shown to..
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