Monthly Archives: abril 2025

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Optimization of carbon dioxide insufflation strategies in minimally invasive cardiac surgery: the efficacy of continuous insufflation protocols with left ventricular…

Abstract Objectives Although CO₂ insufflation play an established role in open-heart surgery, its optimal application in minimally invasive cardiac procedures remains unclear. This study systematically compared continuous versus single CO₂..

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Hemodynamic considerations of ipsilateral versus contralateral cannulation with venoarterial extracorporeal membrane oxygenation

Abstract Objective Patients on venoarterial extracorporeal membrane oxygenation undergoing ipsilateral cannulation may develop distal limb ischemia. We postulate 2 clinical questions: (1) Would contralateral cannulation have a lower distal limb..

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Impact of Intraoperative Hyperoxia Versus Normoxia on Mortality and Organ Injury in Cardiac Surgery: A Systematic Review and Meta-analysis of…

Abstract Objective To compare mortality and organ injury associated with intraoperative hyperoxia and normoxia in cardiac surgery patients. Design Systematic review and meta-analysis of randomized clinical trials (RCTs). Setting Tertiary..

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Flow patterns through side holes of venous cannula in mock circulation loop

Abstract Cannulae with multi-staged side holes (SHs) for venous drainage are widely used for performing extracorporeal circulation. Various types of catheters are used worldwide; however, data on the flow performance..

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Preoperative Extracorporeal Membrane Oxygenation as a Bridge to Cardiac Surgery: Outcomes and Challenges

Abstract Background Outcomes of postcardiotomy extracorporeal membrane oxygenation (ECMO) are well studied, but preoperative ECMO bridging is less studied. This single-center review evaluates outcomes of patients supported with ECMO as..

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Peri-operative Immunoglobulin Dynamics and Infection Risk in Infants Undergoing Congenital Heart Surgery: A Prospective Observational Cohort

Abstract Background:  Infants with congenital heart disease (CHD) frequently undergo surgery during their first year of life. Infants undergoing CHD surgery experience systemic inflammation and haemodilution that can deplete circulating..

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Implantation of integrated magnetically levitated biventricular assist devices (DuoCor) – a single-center clinical experience

Abstract Background:  End-stage heart failure remains a major global health challenge with high mortality. While heart transplantation is the gold-standard treatment, the scarcity of donor hearts necessitates alternative therapies. Left..

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Plasma fibrinogen level and severe bleeding in cardiac surgery: an observational post hoc study of the ALBICS trial

Abstract Purpose Fibrinogen is widely used in cardiac surgery. Still, reported associations between plasma fibrinogen level and chest tube drainage are weak. The results of trials on fibrinogen supplementation are..

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Stroke after aortic arch surgery with short circulatory arrest times: The role of cerebral perfusion strategies

Abstract Background Neuroprotection during aortic arch surgery often involves hypothermia and the use of adjunctive cerebral perfusion. While antegrade cerebral perfusion (ACP) is favored for extended hypothermic circulatory arrest (HCA),..

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Feasibility of Veno-Venous Extracorporeal Membrane Oxygenation Cannulation via the Neck in a Patient With Spinal Cord Injury Wearing a Halo…

Abstract To our knowledge, no previous reports have described the use of veno-venous extracorporeal membrane oxygenation (V-V ECMO) in patients wearing a halo vest. We present a case in which..

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Cardiac index, SvO2 or pCO2 gap may determine benefit from ECMO in cardiogenic shock: post-hoc analysis of the multicenter, randomized…

Abstract Background Immediate initiation of extracorporeal membrane oxygenation (ECMO) has not demonstrated benefit in individuals diagnosed with cardiogenic shock based on the presence of hypotension. The relationship between other hemodynamic..

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Temporary Occlusion of Patent Ductus Arteriosus in Adult during Cardiac Surgery

Abstract INTRODUCTION: Patent ductus arteriosus in adults is rare, and is commonly recommended to be closed due to the possibility of cardiac complications. Patent ductus arteriosus closure has been often performed..

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Specialized Tilt Bed for Mobilization on Femoral Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Cohort Analysis

Abstract Mobilization of patients supported on extracorporeal membrane oxygenation (ECMO)—especially with femoral cannulas—presents unique challenges. This single-center retrospective cohort study aims to assess the efficacy and safety of mobilizing these..

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Prevalence and Predictors of 3 Vital Outcomes After Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Predictors of death resulting from extracorporeal membrane oxygenation (ECMO) withdrawal, in-hospital death after ECMO liberation, and survival to hospital discharge have been evaluated incompletely, despite the prognostic insight..

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Perioperative Resuscitation and Life Support (PeRLS): An Update

Abstract Cardiovascular collapse and arrest in the periprocedural setting and intensive care unit differ from arrests in other contexts (such as out-of-hospital or hospital ward) because clinicians almost always witness..

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High-Caliber Femoral Dual-Lumen Cannula for ECCO2R in Hypercapnic Respiratory Failure: Efficacy and Safety Evaluation

Abstract Extracorporeal carbon dioxide removal (ECCO₂R) prevents intubation and facilitates extubation in patients with hypercapnic respiratory failure. However, low-flow systems increase shear stress and need full anticoagulation, increasing the risk..

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Variability in Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making: An International Survey

Abstract Objective:  To characterize the variability in venovenous extracorporeal membrane oxygenation (VV-ECMO) candidacy decision-making processes across international Extracorporeal Life Support Organization (ELSO) member institutions. Design:  An international survey study of..

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Prophylactic VA-ECMO During Complex High-Risk PCI: A Randomized Controlled Trial

Abstract Background Evidence on prophylactic venoarterial extracorporeal membrane oxygenation (VA-ECMO) during elective percutaneous coronary intervention (PCI) in patients with complex high-risk coronary artery lesions is limited. Objectives The authors aimed..

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Over 30 Years of Neonatal Respiratory Extracorporeal Membrane Oxygenation From a Regional Program

Abstract This referral center’s prospective inception-cohort study from 1989 to 2000 (Era 1) and 2000 to 2022 (Era 2) included 232 consecutive children having neonatal respiratory extracorporeal membrane oxygenation (ECMO)...

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Mitigating the adverse haematological consequences of extracorporeal membrane oxygenation

Abstract Pumping blood through an extracorporeal membrane oxygenation (ECMO) circuit in critically ill patients inevitably leads to a pathophysiological response characterized by platelet and procoagulant activation, fibrin deposition, and immunomodulation. This..

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Prolonged Mechanical Ventilation Prior to Venovenous Extracorporeal Membrane Oxygenation and In-Hospital Mortality in Patients With Acute Respiratory Distress Syndrome

Abstract OBJECTIVES:  To evaluate the relationship between the duration of pre-extracorporeal membrane oxygenation (ECMO) mechanical ventilation and mortality in acute respiratory distress syndrome (ARDS) patients undergoing venovenous ECMO. DESIGN:  Retrospective..

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Cerebrovascular Strokes During Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving mechanical support in patients with cardiogenic shock. There are great variations in the reported rates of neurological complications and associated..

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Clinical and hemodynamic effect of intravenous calcium administration in cardiac surgery: A systematic review

Abstract Background Intravenous calcium is frequently administered in cardiac surgery patients to improve hemodynamics. Objectives To assess safety and efficacy of intravenous calcium administration in this population. Methods We conducted..

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The Spectrum of Mitral Regurgitation in Lung Transplant Recipients: A Systematic Review

Abstract Mitral regurgitation (MR) in lung transplant (LTx) recipients is a rare but complex cardiopulmonary phenomenon. The overlap between symptoms of MR and post-LTx complications, such as primary graft dysfunction,..

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Five Years After Extracorporeal Membrane Oxygenation: A Prospective Cohort Study of Health-Related Quality of Life and Patient Outcomes

Abstract Objectives:  To report on 5-year survival, health-related quality of life (HRQoL), and occupational status of patients with respiratory or cardiac failure, who were supported with extracorporeal membrane oxygenation (ECMO)...

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Cardiac function recovery after 20-min hands-off using thoracoabdominal-normothermic regional perfusion

Abstract Background The increasing prevalence of end-stage heart failure coupled with limited donor organs creates a critical need for novel strategies in heart transplantation. Donation after circulatory death offers a..

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Dextran vs. Crystalloid Priming Solution in Cardiac Surgery: A Randomized Trial on Acute Kidney Injury

Abstract Background Acute kidney injury (AKI) is a frequent complication following cardiac surgery involving cardiopulmonary bypass (CPB). This is partly attributable to crystalloid-based priming solutions causing both hemolysis and loss..

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Construction of a nomogram model for individualized prediction of extracorporeal membrane oxygenation weaning outcomes in cardiogenic shock

Abstract Objective To construct a nomogram prediction model for death in patients with cardiogenic shock after extracorporeal membrane oxygenation (ECMO) weaning. Methods Totally 210 patients with cardiogenic shock treated with..

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The changing spectrum of cardiovascular diseases

Abstract Advances in cardiovascular disease prevention are often hailed as one of the major public health accomplishments of the past 50 years. The progress achieved is rooted in efforts challenging..

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Patient-Specific Susceptibility to the Nadir Oxygen Delivery on Cardiopulmonary Bypass

Abstract Objectives Maintaining a nadir oxygen delivery ≥ 280 mL/min/m2 during cardiopulmonary bypass is a pillar of the goal-directed perfusion strategy in cardiac surgery. However, there are patients who develop a..

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