Monthly Archives: enero 2025

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Thromboelastography in Children Undergoing Extracorporeal Membrane Oxygenation

Abstract Background Children undergoing extracorporeal membrane oxygenation (ECMO) are at risk of hematologic and coagulation complications, including intracranial hemorrhage. Thromboelastography is used to monitor anticoagulation in patients receiving ECMO, but..

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Prospective Observational Study Comparing Systemic Inflammatory Responses Across Different Perfusion Systems During Isolated On-Pump Coronary Artery Bypass Grafting

Abstract Objectives Minimal invasive Extracorporeal Circulation (MiECC) and Hybrid System (HS) have been introduced to potentially reduce the inflammatory response compared to conventional Cardiopulmonary Bypass (cCPB). The HS combines elements..

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Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk

Abstract Importance  Postoperative red blood cell transfusion guidelines recommend transfusion for hemoglobin levels less than 7 g/dL. However, the safety of this strategy in patients at high risk of cardiac events..

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Ethical Considerations for Patients Requiring Extracorporeal Cardiopulmonary Resuscitation

Abstract Immediate recognition of cardiac arrest and the initiation of cardiopulmonary resuscitation (CPR) can significantly improve survival chances. The use of extracorporeal membrane oxygenation during CPR (eCPR) could further enhance..

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Is body mass index associated with hypoxic-ischemic brain injury risk in extracorporeal cardiopulmonary resuscitation?

Abstract Aim To characterize the impact of BMI (body mass index) on HIBI (hypoxic-ischemic brain injury) in patients receiving ECPR, with the hypothesis that elevated BMI is associated with increased..

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Prolonged intra-aortic balloon pump support successfully reversed severe pulmonary hypertension prior to heart transplantation

Abstract Background Heart transplantation remains the gold standard for the treatment of end-stage heart failure, but severe pulmonary hypertension (PH) poses a significant challenge due to the increased risk of..

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Effect of surgical site infection bundles in cardiac surgery: Incidence, microbiology, and risk factors

Abstract Background: Surgical site infections are the second most common type of healthcare-associated infection. Objective: This study aimed to assess the incidence and associated risk factors of surgical site infection..

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Anticoagulation-free strategy within the first 24 h of extracorporeal cardiopulmonary resuscitation in refractory cardiac arrest patients: a retrospective cohort study

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), involving VA-ECMO during refractory cardiac arrest, has been linked to improved outcomes. While systemic anticoagulation is commonly used to prevent circuit thrombosis, bleeding and..

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Arterial Changes After Vascular Reconstruction Following Decannulation From Extracorporeal Life Support: Single-Center, Retrospective Cohort 2002–2022

Abstract Objectives:  Decannulation after pediatric extracorporeal life support (ECLS) may be accompanied by arterial reconstruction. There is a paucity of data on arterial morphology following reconstruction. We sought to characterize..

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Smart technologies and digital innovations for improving perioperative patient safety: a review

Abstract Background Smart digital technologies are rapidly transforming perioperative care through tools such as clinical decision support systems, wearable sensors, and electronic checklists. Despite growing adoption, their specific impact on..

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3D Membrane Microstructures for Increased Efficiency in Blood-Gas Transfer

Abstract Treating severe lung diseases with extracorporeal membrane oxygenation (ECMO) is often accompanied by serious complications, restricting applicability and adversely affecting outcomes. Membrane oxygenators, based on hollow fiber membranes (HFM),..

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Preparation of a cardiopulmonary bypass priming solution for infants and neonates – effect of pre-bypass ultrafiltration on heparinization

Abstract Introduction Heparin is usually added to infant cardiopulmonary bypass circuit primes. Ultrafiltration is often used to minimise prime volume before commencing bypass. The extent of heparin removal from bypass..

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Multidisciplinary Applications of VR & AR Technologies in Professional Training: A Multi-centre Simulation Study

Abstract This study focuses on the impact of virtual reality (VR) technologies on educational processes and professional training, particularly in the fields of medicine, aviation, and the arts. The purpose..

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Multisite Venovenous Extracorporeal Membrane Oxygenation in Pediatric Patients Under 15 kg: Three-Center, Analysis of Surgical Versus Percutaneous Approach and Thrombosis…

Abstract Objectives:  An increasing number of pediatric centers use the femoral vein in neonates and smaller children to provide venovenous multisite (VVMS) extracorporeal membrane oxygenation (ECMO), but there are no..

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Acute Brain Injury in COVID-19 Versus Influenza A Patients on Venovenous Extracorporeal Membrane Oxygenation: A Propensity Score Matching Analysis of…

Abstract Objectives:  Limited data exist on outcomes in COVID-19- vs. influenza A (H1N1)-associated acute respiratory distress syndrome (ARDS) patients when supported on venovenous extracorporeal membrane oxygenation (ECMO). We aimed to..

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Network Meta-Analysis of Axillary, Femoral, and Central Arterial Cannulation in Minimally Invasive Cardiac Surgery

Abstract The optimal arterial cannulation site in minimally invasive cardiac surgery (MICS) remains debated. While axillary, femoral, and central approaches each offer distinct advantages, no prior network meta-analysis has compared..

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The Global Outbreak of M. chimaera Infection Following Cardiac Surgery: Another Piece of the Puzzle

Abstract Invasive cases of Mycobacterium chimaera have been found in Europe, and beyond, and have been associated with the use of heater–cooler units necessary to regulate the temperature of blood in extracorporeal..

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A nitric oxide-releasing organic selenium-grafted phosphorylcholine coating for thrombosis and inflammation prevention in extracorporeal membrane oxygenation

Abstract Thrombosis and inflammation represent major challenges limiting the functionality of asymmetric poly(4-methyl-1-pentene) (PMP) hollow fiber membranes in extracorporeal membrane oxygenation (ECMO) systems. Moreover, the interplay between these two pathological..

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Acquired factor XIII deficiency in adult patients during ECMO: a prospective observational study

Abstract Data on factor XIII (FXIII) activity in patients on extracorporeal membrane oxygenation (ECMO) are scarce. In this prospective, observational, single-centre study, we determined the rate of acquired FXIII deficiency..

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Heart support crossroads: aortic Impella 5.5 implantation compared to conventional axillary approach in combined use of extracorporeal membrane oxygenation and…

Abstract Background: Postcardiotomy shock, often necessitates advanced mechanical circulatory support. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and the Impella 5.5 device are crucial for hemodynamic stabilization. This study evaluates the efficacy and..

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Ventricular Assist Devices and Other Mechanical Circulatory Support Devices: Types, Complications, and Updates

Abstract Mechanical circulatory support devices (MCSDs) have revolutionized the management of advanced heart failure and critical cardiopulmonary conditions. These devices, categorized into temporary and long-term systems, provide crucial circulatory and..

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Hydrogen’s Feasibility and Safety as a Therapy in Extracorporeal Cardiopulmonary Resuscitation (Hydrogen-FAST): study protocol for a trial of inhaled hydrogen…

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival for patients experiencing refractory cardiac arrest but is often associated with severe ischemia-reperfusion injury (IRI). Hydrogen gas (H2) has demonstrated promising preclinical..

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Extracorporeal membrane oxygenation in obstetrical patients: a meta-analysis

Abstract Critically acute and ill and Obstetrical patients constitute a unique clinical population with a high mortality rate. Extracorporeal membrane oxygenation (ECMO) is gradually being used in obstetrical acute and..

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Numerical Analyses of Blood Pumps Under Realistic Operating Conditions

Abstract Computational fluid dynamics (CFD) assessments in blood pumps (BPs) typically rely on constant boundary conditions, despite the dynamic nature of the cardiovascular system. Consensus on CFD methodologies for simulating..

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Surgical Site Infection in Pediatric Patients Undergoing Cardiac Surgery with Delayed Sternal Closure: Experience from a Center in Chile (2015–2020)

Abstract Delayed sternal closure (DSC) is a technique used in complex cardiac surgery (CCS) and is associated with an increased risk of surgical site infection (SSI). SSI increases hospital stay..

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A scoping review: Point-of-care ultrasound (POCUS) use in paediatric ECMO

Abstract Objective This scoping review aimed to examine current literature on the use of point-of-care ultrasound (POCUS) in paediatric patients supported by extracorporeal membrane oxygenation (ECMO). It assessed existing evidence,..

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Renal Angina Index as a Predictor of Renal Injury Progression in Patients on Extracorporeal Membrane Oxygenation Support: The DREAMS Study

Abstract This retrospective cohort study evaluates the validity of the Renal Angina Index (RAI) in predicting acute kidney injury (AKI) in 272 patients receiving extracorporeal membrane oxygenation (ECMO) support. The..

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Strategies to predict and decrease flow rate pulsation in a rotary peristaltic pump with novel tube design

Abstract Peristaltic pumps are commonly used in medical applications like cardiopulmonary bypass and drug infusion due to their minimal contact with bio-fluids and precise flow control. However, these pumps generate..

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Optimization of carbon dioxide insufflation strategies in minimally invasive cardiac surgery: the efficacy of continuous insufflation protocols with left ventricular…

Abstract Objectives Although CO₂ insufflation play an established role in open-heart surgery, its optimal application in minimally invasive cardiac procedures remains unclear. This study systematically compared continuous versus single CO₂..

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Hemodynamic considerations of ipsilateral versus contralateral cannulation with venoarterial extracorporeal membrane oxygenation

Abstract Objective Patients on venoarterial extracorporeal membrane oxygenation undergoing ipsilateral cannulation may develop distal limb ischemia. We postulate 2 clinical questions: (1) Would contralateral cannulation have a lower distal limb..

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