Yearly Archives: 2024

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Accredited cardiac arrest centers facilitate eCPR and improve neurological outcome

Abstract Background Out-of-hospital cardiac arrest (OHCA) remains a frequent medical emergency with low survival rates even after a return of spontaneous circulation (ROSC). Growing evidence supports formation of dedicated teams..

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First experience with the new extracorporeal membrane oxygenation system Colibrì

Introduction Extracorporeal membrane oxygenation (ECMO) is increasingly used for circulatory or pulmonary support not only in-hospital but also out-of-hospital. Small dimensions and a lightweight design are important, especially for out-of-hospital..

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The effect of cardiac rehabilitation on cardiopulmonary function after coronary artery bypass grafting: A systematic review and meta-analysis

Abstract We carried out a meta-analysis on the effect of cardiac rehabilitation (CR) on cardiopulmonary function after coronary artery bypass grafting (CABG). Four databases were searched for studies comparing CR..

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Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC)…

Abstract Background: The  during  (CPB) to improve Recovery in Infants with  (NITRIC) trial, a 1320-patient, multicentre, , is aiming to improve survival free of ventilation after CPB by using nitric oxide delivered into the  of the..

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Emergent Conversion to Open Heart Surgery during Transcatheter Aortic Valve Implantation: The Presence of a Rescue Team Improves Outcomes

Abstract Objective: Transcatheter aortic valve implant (TAVI) is the gold standard for the high-surgical-risk group of patients with aortic valve disease and it is an alternative to surgery in patients..

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Assessment of the well-being of significant others of cardiothoracic surgeons

Abstract Objectives We aimed to evaluate how the current working climate of  surgery and burnout experienced by  surgeons influences their spouses and significant others (SOs). Methods A 33-question well-being survey was developed..

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First report of successful treatment of chronic pediatric tibial osteomyelitis and fracture using autologous platelet-rich plasma

Abstract  is a refractory disease caused by microbial invasion of the bone, leading to destruction of the . It is more common in children. Osteomyelitis requires long  at high cost and is..

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How low can you go: Restrictive transfusion strategies in major surgery and physiological triggers

Abstract Anemia and red blood cell transfusion are associated with adverse outcomes. Large randomized trials have demonstrated that restrictive transfusion strategies can safely reduce patient exposure to transfusion, forming a..

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Epidemiological and Molecular Investigation of the Heater–Cooler Unit (HCU)-Related Outbreak of Invasive Mycobacterium chimaera Infection Occurred in Italy

Abstract Background: From 2013 onwards, a large outbreak of Mycobacterium chimaera (MC) invasive infection, which was correlated with the use of contaminated heater–cooler units (HCUs) during open chest surgery, was reported..

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Effect of Red Blood Cell Transfusion on Regional Tissue Oxygenation in Pediatric Cardiac Surgery Patients

Abstract BACKGROUND:  Red blood cell (RBC) transfusions are used frequently in pediatric patients admitted to the intensive care unit (ICU) after cardiac surgery. To improve data-driven transfusion decision-making in the..

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Cerebral and intestinal oxygen saturation of different volumes of red blood cell transfusion in preterm infants

Abstract Objectives The purpose of this study was to investigate and compare the effects of 20 ml/kg and 15 ml/kg  (RBCT) on cerebral and intestinal tissue oxygenation, the number of administered transfusions, and..

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Utility of heparin-binding protein following cardiothoracic surgery using cardiopulmonary bypass

Abstract Cardiothoracic surgery using cardiopulmonary bypass (CPB) triggers an inflammatory state that may be difficult to differentiate from infection. Heparin-binding protein (HBP) is a candidate biomarker for sepsis. As data..

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Nonresuscitation Fluid Accumulation and Outcomes After Pediatric Cardiac Surgery: Single-Center Retrospective Cohort Study

Abstract OBJECTIVES:  Postoperative patients after congenital cardiac surgery are at high risk of fluid overload (FO), which is known to be associated with poor outcomes. “Fluid creep,” or nonresuscitation IV..

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A new risk predictive scoring system of vasovagal reactions in patients with preoperative autologous blood donation

Abstract Background and objectives  (VVR) is the most common adverse reaction during blood donation and it is the main element for the safety of the patients with preoperative autologous blood..

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Alterations to Kidney Physiology during Cardiopulmonary Bypass—A Narrative Review of the Literature and Practical Remarks

Abstract Introduction: According to different authors, cardiac surgery-associated acute kidney injury (CSA-AKI) incidence can be as high as 20–50%. This complication increases postoperative morbidity and mortality and impairs long-term kidney..

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Nomenclature of Extracorporeal Blood Purification Therapies for Acute Indications: The Nomenclature Standardization Conference

Abstract The development of new extracorporeal blood purification (EBP) techniques has led to increased application in clinical practice but also inconsistencies in nomenclature and misunderstanding. In November 2022, an international..

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Effect of cardiopulmonary bypass on coagulation factors II, VII and X in a primate model: an exploratory pilot study

Abstract OBJECTIVES The use of cardiopulmonary bypass (CPB) in cardiac surgery is a major risk factor for postoperative bleeding. We hypothesized that consumptive coagulopathy and haemodilution influence the coagulation factors;..

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Effects of blood transfusion, cardiopulmonary bypass time, and bypassed vessels on mortality following isolated and combined coronary artery bypass grafting

Abstract Objective: This study aimed to investigate the correlation between the number of bypassed vessels, the duration of Cardiopulmonary bypass, blood transfusion requirements, revision rates, and mortality outcomes. The objective..

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Diffuse Optical Monitoring of Cerebral Hemodynamics and Oxygen Metabolism during and after Cardiopulmonary Bypass: Hematocrit Correction and Neurological Vulnerability

Abstract Cardiopulmonary bypass (CPB) provides cerebral oxygenation and blood flow (CBF) during neonatal congenital heart surgery, but the impacts of CPB on brain oxygen supply and metabolic demands are generally..

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Dilemmas of Adopting Goal-Directed Perfusion in Extracorporeal Circulation: A Narrative Review

Abstract Objective: Extracorporeal circulation (ECC) is generally based on standards established in the last decade. In recent years, a concept of perfusion management during ECC, goal-directed perfusion (GDP), has emerged..

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Catastrophic Mechanical Complications of Extracorporeal Membrane Oxygenation

Abstract Technical advances in extracorporeal membrane oxygenation (ECMO) have increased the number of cases that maintain longer duration. Long-term use of ECMO results in ECMO-related complications. Anticipation of the life-threatening..

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Modeling and estimating a threshold effect: An application to improving cardiac surgery practices

Abstract Estimating thresholds when a threshold effect exists has important applications in biomedical research. However, models/methods commonly used in the biomedical literature may lead to a biased estimate. For patients..

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Transesophageal Echocardiography Guided Veno-Pulmonary Extracorporeal Membrane Oxygenation Cannula Insertion Technique

Abstract For single-lumen veno-pulmonary extracorporeal membrane oxygenation (VP ECMO) cannulation in percutaneous technique, vascular ultrasound (U/S) and transesophageal echocardiography (TEE) guidance were used to insert a 7 Fr pulmonary artery..

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The microcirculation in perioperative medicine: a narrative review

Abstract The  describes the network of the smallest vessels in our cardiovascular system. On a microcirculatory level, oxygen delivery is determined by the flow of oxygen-carrying  in a given single capillary (capillary..

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Mechanical Ventilation During Extracorporeal Membrane Oxygenation—Getting the Oxygenation Right

Abstract I read with keen interest the article by van Minnen et al. on contemporary mechanical ventilation strategies during extracorporeal membrane oxygenation (ECMO). The article specifies details on ventilation practices employed in..

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ECMOve: A Mobilization Device for Extracorporeal Membrane Oxygenation Patients

Abstract Extracorporeal membrane oxygenation (ECMO) is a temporary lifesaving treatment for critically ill patients with severe respiratory or cardiac failure. Studies demonstrated the feasibility of in-hospital mobilizing during and after..

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Extracorporeal Membrane Oxygenation in Cardiogenic Shock: Execution Is Something; Timing Is Everything?

Abstract Cardiogenic shock (CS) is a complex and life‐threatening condition characterized by a sudden and profound reduction in cardiac output, leading to inadequate tissue perfusion and oxygen delivery and organ..

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Direct Apical Cannulation With Protek Duo Rapid Deployment Cannula via Mini Thoracotomy for Ambulatory Venoarterial-Extracorporeal Membrane Oxygenation

Abstract National trends show rapid increases in the use of mechanical circulatory support devices (MCSD) over the last 20 years. While current literature has not proven a mortality benefit in..

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