Abstract Cardiac surgery with cardiopulmonary bypass results in global myocardial ischemia–reperfusion injury, leading to significant postoperative morbidity and mortality. Although cardioplegia is the cornerstone of intraoperative cardioprotection, a number of..
Read MoreAbstract Introduction Polymethylpentene (PMP) oxygenators serve as the primary oxygenator type utilized for ECMO. With the number of PMP oxygenators available, it has become increasingly important to determine differences among..
Read MoreAbstract Background Cardiac arrest is associated with high mortality rates and severe neurological impairments. One of the underlying mechanisms is global ischemia-reperfusion injury of the body, particularly the brain. Strategies..
Read MoreAbstract Objectives To evaluate the impact of on transition to chronic (CKD) after cardiac surgery and to determine frequency of incident CKD in these patients. Design A and meta-analysis of observational studies. Setting..
Read MoreAbstract Cardiac arrest is a hyper-acute condition with a high mortality that requires rapid diagnostics and treatment. As such, point-of-care ultrasound (POCUS) has become a valuable tool in the assessment..
Read MoreAbstract Introduction Perfusion safety in cardiac surgery is vital, and this survey explores perfusion practices, perspectives, and challenges related to it. Specifically, it examines the readiness of on-call and emergency..
Read MoreAbstract The purpose of this viewpoint is to provide awareness of the current opportunities to enhance a high-value care approach to blood product transfusion. It provides a historical context to..
Read MoreIntroduction Managing acute respiratory distress syndrome (ARDS) poses significant challenges due to its heterogeneous nature. As of 2024, the updated global definition of ARDS now includes patients receiving noninvasive ventilation..
Read MoreThe Nephroprotective Effect of Nitric Oxide during Extracorporeal Circulation: An Experimental Study
Abstract This study aims to determine the effectiveness of administering 80 ppm nitric oxide in reducing kidney injury, mitochondrial dysfunction and regulated cell death in kidneys during experimental perfusion. Twenty-four..
Read MoreAbstract Pulmonary hypertension (PH) is a frequent condition in patients with heart failure (HF), which complicates the course of the HF syndrome. Irrespective of left ventricular ejection fraction (LVEF), PH is..
Read MoreIntroduction Patients with the clinical and biochemical signs and symptoms of hypoperfusion secondary to cardiac failure or cardiac arrest carry high short-term mortality. Various mechanical circulatory devices have been developed to..
Read MoreAbstract Obesity is often considered a contraindication to extracorporeal membrane oxygenation (ECMO) candidacy due to technical challenges with vascular access, higher cardiac output requirements, and known associations between obesity and..
Read MoreMy background as a mentor To provide some context to my involvement in this discussion and to outline my foundation in mentorship, I would like to offer a brief overview..
Read MoreAbstract Objective The mismatch between the demand for and supply of organs for transplantation is steadily growing. Various strategies have been incorporated to improve the availability of organs, including organ..
Read MoreAbstract Objectives Symptomatic neonates and infants with Ebstein anomaly (EA) require complex management. A group of experts was commissioned by the American Association for Thoracic Surgery to provide a framework..
Read MoreAbstract Introduction: Cardiopulmonary bypass is an essential component of cardiothoracic surgeries. However, significant complications such as systemic inflammatory response syndrome (SIRS) resulting from cardiopulmonary bypass (CPB) are a common occurrence..
Read MoreAbstract Adequate fluid management in the in paediatric patients is essential for restoring and maintaining homeostasis and ensuring adequate . A well-designed infusion regimen is crucial for preventing severe complications such as hyponatraemic encephalopathies...
Read MoreAbstract Despite multimodal treatment of patients with (CS) complicating (AMI), the outcome remains poor. Large retrospective analyses and animal models suggest that (ECLS) in CS-complicating AMI improves outcome . However, to date, no assessing the..
Read MoreAbstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) support is a lifesaving tool in cardiovascular care, providing excellent hemodynamic assistance for numerous indications, such as cardiogenic shock or periprocedural support in patients..
Read MoreAbstract Objective Failure to receive prompt leads to severe complications if massive occurs during surgery. For the timely preparation of blood products, predicting the possibility of massive transfusion (MT) is essential to..
Read MoreAbstract OBJECTIVES Multi-organ failure is one of the leading causes of mortality after cardiac surgery for infective endocarditis (IE). Although the randomized evidence does not support the use of haemoadsorption..
Read MoreAbstract Introduction For Jehovah’s Witness (JW) patients requiring cardiac surgery, various strategies such as preoperative use of erythropoietin stimulating agents (ESAs), intravenous iron (IVI), and non-pharmacologic interventions have emerged to..
Read MoreAbstract We read with great interest Pavlov’s letter to the editor on oxygenation targets and optimization of mechanical ventilation (MV) during extracorporeal membrane oxygenation. Adding FiO2 titration strategy would have been..
Read MoreAbstract Blood surface interfacing that occurs within the extracorporeal membrane oxygenation (ECMO) circuit initiates contact activation, an important hemostatic pathway initiated by the Hageman factor, also called factor XII. Factor..
Read MoreAbstract Purpose Veno-arterial extracorporeal life support (ECLS) is increasingly used in patients during cardiac arrest and cardiogenic shock, to support both cardiac and pulmonary function. We performed a systematic review..
Read MoreAbstract OBJECTIVES: To examine trends in utilization and outcomes among patients with the acute respiratory distress syndrome (ARDS) requiring prolonged venovenous extracorporeal membrane oxygenation (VV ECMO) support. DESIGN: Retrospective observational..
Read MoreAbstract Purpose of review Discussing the rationale and current evidence for left ventricular unloading in cardiogenic shock. Recent findings Microaxial flow pumps (MFP) and intra-aortic balloon pumps (IABP) augment cardiac..
Read MoreAbstract The HeartMate PHP (percutaneous heart pump) is a second-generation transcatheter axial flow circulatory support system. The collapsible catheter pump is inserted through a 14 Fr sheath, deployed across the..
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