Yearly Archives: 2024

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Students’ approaches to developing scientific communication skills

Abstract Science communication is a core skill for undergraduate science students to acquire in preparation for their future careers, but studies show that this skill is underdeveloped in science graduates...

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Heparin-Bead Extraction Enhanced Fluorogenic Aptamer–Thrombin Composite Reporter Enables Sensitive and Rapid Detection of Functional Antithrombin

Abstract Antithrombin (AT) deficiency in the extracorporeal circulation during cardiac surgery leads to uncontrolled inflammation and vascular damage in patients. AT levels decrease in sepsis, major trauma, extracorporeal membrane oxygenation,..

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Sourcebook update: using near-infrared spectroscopy to assess skeletal muscle oxygen uptake

Abstract Monitoring the metabolic cost or oxygen consumption associated with rest and exercise is crucial to understanding the impact of disease or physical training on the health of individuals. Traditionally,..

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Intraoperative Oxygen Treatment, Oxidative Stress, and Organ Injury Following Cardiac Surgery

Abstract Importance  Liberal oxygen (hyperoxia) is commonly administered to patients during surgery, and oxygenation is known to impact mechanisms of perioperative organ injury. Objective  To evaluate the effect of intraoperative hyperoxia compared..

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Cardiopulmonary Bypass Blood Flow Rates and Major Adverse Kidney Events in Cardiac Surgery: A Propensity Score-adjusted Before–After Study

Abstract Objectives Cardiac surgery associated-acute kidney injury is a common and serious postoperative complication of cardiac surgery, which is associated with increased postoperative morbidity and mortality. This study aimed to..

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2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP

Abstract Cardiac surgery is a distinctive surgical discipline that often necessitates the use of cardiopulmonary bypass (CPB) and full anticoagulation intraoperatively, along with varying levels of antithrombotic treatments both before..

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“Not an ECMO Candidate”: An exploratory analysis of patients declined for VA-ECMO

Abstract Background: Patient selection for extracorporeal membrane oxygenation (ECMO) support is complex and associated with variability between clinicians. Disparities exist in ECMO use, with lower utilization in patients who are female,..

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Factors associated with acute kidney injury after on-pump coronary artery bypass grafting

Abstract Background Acute kidney injury (AKI) frequently occurs as a complication of cardiac surgery and cardiopulmonary bypass (CPB). Its prevalence and severity are determined by various preoperative and intraoperative factors...

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Overcoming Obstacles in Remote ECPR:A Success Story from Initial Resuscitation to LVAD

Abstract Introduction: In remote hospital settings, providing timely and effective extracorporeal cardiopulmonary resuscitation (ECPR) is challenging due to infrastructure limitations and accessibility issues. We are highlighting the importance of grab-and-go ECPR..

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Impact of a Daily Huddle on Safety in Perioperative Services

Abstract Background Communication failures contribute to quality gaps and may lead to serious safety events (SSEs) in the operating room (OR). Our perioperative services team experienced an increased rate of..

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Mitigating the Stigma of Severe Obesity: BMI ≥ 35 kg/m2 is not a Contraindication to Extracorporeal Support

Abstract Background: A body mass index (BMI) ≥ 35 kg/m² is traditionally a contraindication to extracorporeal support. We evaluated outcomes and quality of life (QoL) associated with veno-venous extracorporeal membrane oxygenation (VV-ECMO)..

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Outcomes of ECMO as a Bridge to Cardiac Surgery

Abstract Introduction: Although outcomes of post-cardiotomy extracorporeal membrane oxygenation (ECMO) are well studied1, the outcomes of patients bridged to cardiac surgery with ECMO are less well understood. We undertook this study..

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Neurological monitoring and management for adult extracorporeal membrane oxygenation patients: Extracorporeal Life Support Organization consensus guidelines

Abstract Background Critical care of patients on extracorporeal membrane oxygenation (ECMO) with acute brain injury (ABI)is notable for a lack of high‑quality clinical evidence. Here, we offer guidelines for neurological..

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Altered Microvascular Reactivity During a Skin Thermal Challenge Is Associated With Organ Dysfunction and Slow Recovery After Cardiac Surgery

Abstract Objectives To assess microvascular reactivity during a skin thermal challenge early post-cardiac surgery and its association with outcomes. Design Noninvasive physiological study. Setting Thirty-five-bed department of intensive care. Participants..

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Different ECLS Pump Configurations for Temporary Right Ventricular Assist Device in LVAD Patients: A Retrospective Case–Control Study

Abstract Background: Acute right ventricular failure is a critical complication after left ventricular assist device (LVAD) implantation, often managed with a temporary paracorporeal right ventricular assist device (RVAD). This study..

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Perfusionist education in Japan: A survey of challenges and current status

Abstract Introduction This study aimed to examine the educational challenges faced by perfusionists in Japan. Although Japan has over 400 cardiovascular surgery centers, it performs fewer surgeries than by countries..

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A narrative review on antimicrobial dosing in adult critically ill patients on extracorporeal membrane oxygenation

Abstract The optimal dosing strategy of antimicrobial agents in critically ill patients receiving extracorporeal membrane oxygenation (ECMO) is unknown. We conducted comprehensive review of existing literature on effect of ECMO..

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Effect of nitric oxide delivery via cardiopulmonary bypass circuit on postoperative oxygenation in adults undergoing cardiac surgery (NOCARD trial): a…

Abstract BACKGROUND  Cardiac surgery involving cardiopulmonary bypass induces a significant systemic inflammatory response, contributing to various postoperative complications, including pulmonary dysfunction, myocardial and kidney injuries. OBJECTIVE  To investigate the effect..

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Potential Impact of Direct Versus Indirect Central Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) Cannulation in Refractory Postcardiotomy Cardiogenic Shock

Abstract Background Central venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly employed strategy to support patients in refractory postcardiotomy cardiogenic shock (RPCS). This support can be provided using either indirect..

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Comprehensive perioperative blood management in patients undergoing elective bypass cardiac surgery: Benefit effect of health care education and systematic correction…

Abstract Study objective The aim of this study was to investigate the efficacy of a two-step patient blood management (PBM) program in red blood cell (RBC) transfusion requirements among patients..

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Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi…

Abstract Purpose: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an integral part of the management algorithm of patients with severe respiratory failure refractory to evidence-based conventional treatments. Right ventricular injury (RVI)..

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Evaluation of Point-of-Care-Directed Coagulation Management in Pediatric Cardiac Surgery

Abstract Background Coagulatory alterations are common after pediatric cardiac surgery and can be addressed with point-of-care (POC) coagulation analysis. The aim of the present study is to evaluate a preventive..

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International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates-2024

Abstract The “International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates—2024” updates and replaces the “Listing Criteria for Heart Transplantation: International Society..

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Use of colloids and crystalloids for perioperative clinical infusion management in cardiac surgery patients and postoperative outcomes: a meta-analysis

Abstract Background The optimal fluid management strategy for patients undergoing cardiac surgery was controversial regarding fluid volume and intraoperative fluid types. This study aimed to assess the correlation between colloids..

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Temperature and Neurologic Outcomes in Neonates Undergoing Cardiac Surgery: A Society of Thoracic Surgeons Study

Abstract Background There is significant variability in postoperative neurological injury rates in patients with , with early injuries impacting long-term neurodevelopmental outcomes; therefore, there is an urgent need for identifying effective..

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Is there a role for extracorporeal membrane oxygenation in children with acute liver failure? A retrospective analysis of the Extracorporeal…

Abstract Data describing the use of extracorporeal membrane oxygenation (ECMO) in pediatric acute liver failure (PALF) are scarce. Thus, we aimed to describe the use of ECMO in patients with..

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Nomogram Model for Cardiac Surgery-Associated Acute Kidney Injury Based on Clinical Characteristics Combined with Plasma suPAR

Abstract Objective: Analyze risk factors for cardiac surgery-associated acute kidney injury (CSA-AKI) in adults and establish a nomogram model for CSA-AKI based on plasma soluble urokinase-type plasminogen activator receptor (suPAR) and..

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Evaluation of university and training standards in clinical perfusion, an European-wide survey

Abstract OBJECTIVES Adequate theoretical and practical training of prospective clinical perfusionists is essential for maintaining clinical standards and ensuring patient safety during cardiac surgery procedures. Perfusion schools play a crucial..

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Uncommon and Unfavorable: Heparin-Induced Hyperkalemia

Abstract Case Report A 56-year-old male with a medical history significant for coronary artery disease complicated by non-ST segment elevation myocardial infarction in 2011 (at which time he received a..

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Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates…

Abstract Background The CRUCIAL trial (NCT04217421) is investigating the effect of postnatal and perioperative administration of allopurinol on postoperative brain injury in neonates with critical congenital heart disease (CCHD) undergoing..

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