Yearly Archives: 2021

thumbnail
0 comment

When all else fails: extracorporeal life support in therapy-refractory cardiogenic shock

Abstract OBJECTIVES No guidelines for mechanical circulatory support in patients with therapy-refractory cardiogenic shock and multiorgan failure including ongoing cardiopulmonary resuscitation (CPR) exist. To achieve immediate cardiopulmonary stabilization, we established..

Read More
thumbnail
0 comment

Cerebral oxygenation during changes in vascular resistance and flow in patients on cardiopulmonary bypass – a physiological proof of concept…

Abstract Despite a rise in blood pressure, cerebral oxygenation decreases following phenylephrine administration, and we hypothesised that phenylephrine reduces cerebral oxygenation by activating cerebral α1 receptors. We studied patients on cardiopulmonary..

Read More
thumbnail
0 comment

Physiology of oxygen transport

Abstract Oxygen is vital for life-sustaining aerobic respiration in humans and is arguably the most commonly administered drug in anaesthesia and critical care medicine. Within the mitochondrial inner membrane, oxygen..

Read More
thumbnail
0 comment

Nitric oxide administration during paediatric cardiopulmonary bypass: a randomised controlled trial

Abstract Purpose Cardiopulmonary bypass induces an ischaemia–reperfusion injury and systemic inflammatory response, which contributes to low cardiac output syndrome following cardiac surgery. Exogenous nitric oxide during cardiopulmonary bypass has shown..

Read More
thumbnail
0 comment

A derived and validated score to predict prolonged mechanical ventilation in patients undergoing cardiac surgery

Abstract Objectives Prolonged  after cardiac surgery imposes a significant burden on the patient in terms of morbidity as well as a financial burden on the hospital. We undertook a retrospective analysis..

Read More
thumbnail
0 comment

Intra-Aortic Balloon Pump Counterpulsation in the Post-Resuscitation Period is Associated with Improved Functional Outcomes in Patients Surviving an Out-of-Hospital Cardiac…

Abstract Background Despite advances in cardiopulmonary resuscitation, functional survival remains low after  (OOHCA).  (IABP) therapy has recently been shown to augment cerebral blood flow. Whether  therapy in the post-resuscitation period improves functional outcomes..

Read More
thumbnail
0 comment

Transition of intestinal fatty acid-binding protein on hypothermic circulatory arrest with cardiopulmonary bypass

Abstract Introduction: Intestinal fatty acid-binding protein (I-FABP) is increasingly employed as a highly specific marker of intestinal necrosis. However, the value of this marker associated with cardiovascular surgery with hypothermic..

Read More
thumbnail
0 comment

Hemiarch: The Real Operation for Ascending Aortic Aneurysm

Abstract The extent and technique of resection for ascending aortopathies remains debated. The 2 main camps are divided into those who believe in the hemiarch resection utilizing hypothermic circulatory arrest..

Read More
thumbnail
0 comment

Prolonged pulmonary support after cardiac surgery: incidence, risk factors and outcomes: a retrospective cohort study

Abstract Background Post–cardiac surgery pulmonary dysfunction may be underreported. Therefore, we evaluated associated risk factors for prolonged pulmonary support after cardiac surgery. Methods and materials We conducted a retrospective, observational..

Read More
thumbnail
0 comment

A Novel Anti-Pollution Filter for Volatile Agents During Cardiopulmonary Bypass: Preliminary Tests

Abstract Objective Concerns regarding pollution of the operating room by  and effects on atmospheric ozone depletion exist.  commonly are used during  to provide  independent of any supposed myocardial protective effects. The authors’ aim was..

Read More
thumbnail
0 comment

Protamine reduces whole blood platelet aggregation after cardiopulmonary bypass

Abstract Objectives: Platelet dysfunction is an important cause of postoperative bleeding after cardiac surgery. Protamine is routinely used for reversal of heparin after cardiopulmonary bypass (CBP), but may affect platelet..

Read More
thumbnail
0 comment

The Munich Lung Transplant Group: Intraoperative Extracorporeal Circulation in Lung Transplantation

Abstract Background This retrospective single-center study aimed to analyze transfusion requirements, coagulation parameters, and outcome parameters in patients undergoing lung transplantation (LuTx) with intraoperative extracorporeal circulatory support, comparing cardiopulmonary bypass..

Read More
thumbnail
0 comment

Concomitant atrial fibrillation surgery for people undergoing cardiac surgery

Abstract Background People with atrial fibrillation (AF) often undergo cardiac surgery for other underlying reasons and are frequently offered concomitant AF surgery to reduce the frequency of short‐ and long‐term..

Read More
thumbnail
0 comment

Outcome Comparison in Children Undergoing Extracorporeal Life Support Initiated at a Local Hospital by a Mobile Cardiorespiratory Assistance Unit or…

Abstract Purpose:  To compare characteristics and outcome in children undergoing extracorporeal life support initiated in an extracorporeal life support center or at the patient’s bedside in a local hospital, by..

Read More
thumbnail
0 comment

Potential identification of a claudicant group vulnerable to acute kidney injury

Abstract This observational study aimed to investigate the relationship between renal injury, endothelial function and oxidative stress in claudicants undergoing maximal treadmill exercise. Twenty patients with claudication were identified in..

Read More
thumbnail
0 comment

Effects of circuit albumin coating on coagulation and inflammatory response for patients receiving aortic arch replacement: a randomized controlled trial

Abstract Objective: To investigate whether human serum albumin coating before cardiopulmonary bypass (CPB) could improve platelet function and hemostasis and mitigate the inflammatory response among patients receiving aortic arch replacement..

Read More
thumbnail
0 comment

Use of Polypropylene and Polymethylpentene (PMP) Fibers for ECMO Oxygenators

Learn about the construction on hollow fiber oxygenators and the use of these for ECMO and cardiac surgery. Learn the reason for fiber wetting and failure and how fiber construction..

Read More
thumbnail
0 comment

2010 (Español) Guía de práctica clínica de la ESC para el manejo de cardiopatías congénitas en el adulto

PREÁMBULO Las Guías de Práctica Clínica resumen y evalúan toda la evidencia relevante sobre un tema particular para ayudar a los médicos a seleccionar la mejor estrategia posible de tratamiento..

Read More
thumbnail
0 comment

2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American…

Preamble Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. These..

Read More
thumbnail
0 comment

2020 ESC Guidelines for the management of adult congenital heart disease: The Task Force for the management of adult congenital…

1 Preamble Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines..

Read More
thumbnail
0 comment

2010. ESC Guidelines for the management of grown-up congenital heart disease (new version 2010)

The Task Force on the Management of Grown-up Congenital Heart Disease of the European Society of Cardiology (ESC) Endorsed by the Association for European Paediatric Cardiology (AEPC) Guidelines summarize and..

Read More
thumbnail
0 comment

New mobile cardiac program extends reach of lifesaving treatment

While ECMO can work miracles, restoring life and health to patients whose hearts have ceased to function, the technology can only help if a patient can be connected to the..

Read More
thumbnail
0 comment

Dynamic Predictive Scores for Cardiac Surgery–Associated Acute Kidney Injury

Abstract Background Cardiac surgery–associated acute kidney injury (CSA‐AKI) is a common complication with a poor prognosis. In order to identify modifiable perioperative risk factors for AKI, which existing risk scores are..

Read More
thumbnail
0 comment

Effect of Oxygenator Size on Air Removal Characteristics: A Clinical Evaluation

Abstract During cardiopulmonary bypass (CPB), gaseous microemboli (GME) are released into the patients’ arterial bloodstream. Gaseous microemboli may contribute to the adverse outcome after cardiac surgery. Recently, two oxygenator models..

Read More
thumbnail
0 comment

Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients

Abstract BACKGROUND:  The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest..

Read More
thumbnail
0 comment

Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial

Abstract Purpose Postoperative cognitive dysfunction (POCD) occurs frequently after cardiac surgery. The pathophysiology of POCD remains elusive, but previous work showed that intravenous lidocaine may be protective against POCD, possibly..

Read More
thumbnail
0 comment

Efficacy of the RemoweLL cardiotomy reservoir for fat and leucocyte removal from shed mediastinal blood: a randomized controlled trial

Abstract Introduction: Re-transfusion of lipid particles and activated leucocytes with shed mediastinal blood (SMB) can aggravate cardiopulmonary bypass-associated inflammation and increase the embolic load. This study evaluated the fat and..

Read More
thumbnail
0 comment

Percutaneous mechanical circulatory support: current concepts and future directions

Abstract Introduction Percutaneous mechanical circulatory support (MCS) strategies have been in the clinical arena for approximately half a century, with the main aim of providing adequate systemic tissue perfusion, while..

Read More
thumbnail
0 comment

Extracorporeal Membrane Oxygenation for Pediatric Respiratory Failure: Risk Factors Associated With Center Volume and Mortality*

Abstract Objectives:  Recent analyses show higher mortality at low-volume centers providing extracorporeal membrane oxygenation. We sought to identify factors associated with center volume and mortality to explain survival differences and..

Read More
thumbnail
0 comment

Establishment of reference intervals and transfusion criterion for Sonoclot analysis

Abstract Sonoclot analyzer has been widely used in many countries. But the reference intervals provided by the manufacturer were derived from only 45 participants, and there was no cut-off value..

Read More