Yearly Archives: 2021

Perfusfind S.L.

Abstract OBJECTIVES This study investigates the effects of high glucose content on patients undergoing cold crystalloid versus cold blood cardioplegia in terms of early clinical results, functional myocardial recovery and..

Perfusfind S.L.

Abstract Minimal invasive extracorporeal circulation (MiECC) systems have initiated important efforts within science and technology to further improve the biocompatibility of cardiopulmonary bypass components to minimize the adverse effects and..

Perfusfind S.L.

Abstract Background and Aims: Cardiopulmonary bypass induces a systematic inflammatory response, which is partly understood by investigation of peripheral blood cytokine levels alone; the lungs may interfere with the net..

Perfusfind S.L.

Abstract This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at . Further information..

Perfusfind S.L.

  Since its first clinical use in the 1950s, the set-up and management of the heart-lung machine (HLM) has been the responsibility of the perfusionist, who has a documented competency..

Perfusfind S.L.

Abstract Sepsis is aggravated by an inappropriate immune response to invading microorganisms, which occasionally leads to multiple organ failure. Several lines of evidence suggest that the ventricular myocardium is depressed..

Perfusfind S.L.

Abstract OBJECTIVES We sought to evaluate the effect of centre volume on survival when extracorporeal membrane oxygenation (ECMO) is used as a bridge to lung transplantation (LTx). METHODS We performed..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) represents a valuable and rapidly evolving therapeutic option in patients with severe heart or lung failure following cardiovascular surgery. However, despite significant advances in..

Perfusfind S.L.

Abstract Traditional venovenous (VV) extracorporeal membrane oxygenation (ECMO) for respiratory failure requires deep sedation and immobilization of patients, both of which carry high morbidity and mortality rates. Technological innovation has..

Perfusfind S.L.

Abstract Background Extracorporeal carbon dioxide removal (ECCO2R) has been gaining interest to potentially facilitate gas transfer and equilibrate mild to moderate hypercapnic acidosis, when standard therapy with non-invasive ventilation is..

Perfusfind S.L.

Abstract OBJECTIVES Aortic valve replacement (AVR) with sutureless bioprostheses has become an alternative to conventional AVR for patients with intermediate to high operative risk. However, this technique is associated with..

Perfusfind S.L.

Abstract Background Fibrinogen supplementation has been proposed both to prevent and treat postoperative bleeding in cardiac surgery. The optimal fibrinogen concentration trigger and target values and the fibrinogen concentrate dose..

Perfusfind S.L.

Abstract OBJECTIVES To investigate the sterility and biocompatibility of a stored open-reservoir cardiopulmonary bypass circuit maintained on standby. METHODS A total of four cardiopulmonary bypass circuits were assembled, primed and..

Perfusfind S.L.

Abstract OBJECTIVES Chronic thromboembolic pulmonary hypertension is the only curable form of pulmonary arterial hypertension. Pulmonary endarterectomy (PEA) has been established as the treatment of choice in these patients producing..

Perfusfind S.L.

Abstract Background.  Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to..

Perfusfind S.L.

Abstract Background.  The mechanisms causing increased endothelial permeability after cardiopulmonary bypass (CPB) have not been elucidated. Using a bioassay for endothelial barrier function, we investigated whether endothelial hyperpermeability is associated..

Perfusfind S.L.

Abstract Background.  Bleeding remains a severe complication in cardiac surgery. Several studies have found an association between the preoperative plasma concentration of fibrinogen and postoperative bleeding in cardiac surgery patients...

Perfusfind S.L.

Abstract A best evidence topic was written according to a structured protocol. The question addressed was whether on-pump beating heart coronary artery bypass (BH-ONCAB) surgery has a different outcome profile..

Perfusfind S.L.

Abstract A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether beating-heart on-pump coronary artery bypass grafting (BH-ONCAB) offered superior mortality..

Perfusfind S.L.

Abstract Background Open heart surgeries under cardiopulmonary bypass are associated with excessive perioperative bleeding that often requires reoperation. Antifibrinolytics like epsilon aminocaproic acid and tranexamic acid are widely used to..

Perfusfind S.L.

Abstract OBJECTIVES There are few data concerning the impact of preoperative renal function, assessed using estimated glomerular filtration rate, on surgical outcomes following acute type A aortic dissection. We investigated..

Perfusfind S.L.

  Welcome to the second collection of articles on the care of cardiac surgery patients in the intensive care unit. While the first installment covered the classic populations of cardiac..

Perfusfind S.L.

Abstract Objective:  To assess the safety and efficacy of combining extracorporeal CO2 removal with continuous renal replacement therapy in patients presenting with acute respiratory distress syndrome and acute kidney injury. Design: ..

Perfusfind S.L.

Abstract OBJECTIVES To investigate the sterility and biocompatibility of a stored open-reservoir cardiopulmonary bypass circuit maintained on standby. METHODS A total of four cardiopulmonary bypass circuits were assembled, primed and..

Perfusfind S.L.

Abstract The provision of continuous renal replacement therapies (CRRT) to small children has generally required the adaptation of adult machines and modified operational characteristics. CRRT prescription for younger and smaller..

Perfusfind S.L.

Abstract Modern day cardiac surgery evolved upon the advent of cardiopulmonary bypass machines (CPB) in the 1950s. Following this development, cardiac surgery in recent years has improved significantly. Despite such..

Perfusfind S.L.

Abstract A high neutrophil-lymphocyte ratio (N/L ratio) was associated with the development of acute kidney injury (AKI) in patients with severe sepsis. We sought to investigate the association between the..

Perfusfind S.L.

Abstract Introduction:  Propofol has been suggested as a useful adjunct to cardiopulmonary bypass (CPB) because of its potential protective effect on the heart mediated by a decrease in ischemia-reperfusion injury..

Perfusfind S.L.

Abstract A best evidence topic was written according to a structured protocol. The clinical question investigated was: is low serum albumin associated with postoperative complications in patients undergoing cardiac surgery?..

Perfusfind S.L.

Abstract Despite the growing body of evidence evaluating the efficacy of vasoactive agents in the management of hemodynamic instability and circulatory shock, it appears no agent is superior. This is..