Yearly Archives: 2021

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Unconscious (Implicit) Bias

Abstract Recognition, acknowledgment, and acceptance of biases in a nonjudgmental manner is key to advancing knowledge and avoiding biased behaviors. Unconscious biases do not mean people are bad, and they..

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The association between intraoperative cell salvage and red blood cell transfusion in cardiac surgery – an observational study in a…

Abstract Cardiac surgery is commonly associated with high blood loss and the need for allogeneic red blood cell (RBC) transfusion. In addition, 20–30% of cardiac surgical patients suffer from anaemia..

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Cardiac Biomarkers for Risk Stratification of Acute Kidney Injury After Pediatric Cardiac Surgery

Abstract Background Children undergoing a cardiac surgical procedure are at increased risk for acute kidney injury (AKI). Novel biomarkers are needed to improve risk stratification of AKI after cardiac surgery...

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Prepump autologous blood collection is associated with reduced intraoperative transfusions in aortic surgery with circulatory arrest: A propensity score-matched analysis

Abstract Objective To evaluate the effect of autologous whole blood (AWB) collection on intraoperative/postoperative allogeneic blood transfusion rate in complex aortic surgery with hypothermic circulatory arrest. Methods This retrospective study..

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Vasopressor Therapy in Cardiac Surgery—An Experts’ Consensus Statement

Abstract Hemodynamic conditions with reduced  commonly are observed in patients undergoing cardiac surgery and may range from moderate reductions in , as a side effect of general anesthetics, to a profound vasodilatory..

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Dual veno-arterial extra-corporeal membrane oxygenation support in a patient with refractory hyperdynamic septic shock: a case report

Abstract The hypodynamic septic shock appears to be a promising indication to veno-arterial membrane oxygenation (VA-ECMO) support of a patient with insufficient cardiac output. With cardiac recovery most of those..

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A Computational Fluid Dynamics Study of the Extracorporeal Membrane Oxygenation-Failing Heart Circulation

Abstract Extracorporeal membrane oxygenation (ECMO) is increasingly deployed to provide percutaneous mechanical circulatory support despite incomplete understanding of its complex interactions with the failing heart and its effects on hemodynamics and perfusion...

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The diagnostic accuracy of procalcitonin in infectious patients after cardiac surgery: a systematic review and meta-analysis

Abstract Cardiac surgery with cardiopulmonary bypass (CPB) induces an acute inflammatory response that may lead to a systemic inflammatory response syndrome. The interest in procalcitonin (PCT) in the diagnosis of..

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Anticoagulation and Transfusion Management During Neonatal and Pediatric Extracorporeal Membrane Oxygenation

Abstract Objectives:  To compare current practices within the United States of anticoagulation management and blood transfusion in neonatal and pediatric extracorporeal membrane oxygenation patients with a 2013 international report. Design: ..

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Point-of-Care Platelet Function Monitoring: Implications for Patients With Platelet Inhibitors in Cardiac Surgery

Abstract Although most physicians are comfortable managing the limited  effect of aspirin, the recent administration of potent P2Y12 receptor inhibitors in patients undergoing cardiac surgery remains a dilemma. Guidelines recommend discontinuation of..

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Peer-review of “A history of cardiac surgery: an adventurous voyage from antiquity to the artificial heart” by Ugo Filippo Tesler

Abstract The storytelling of contemporary cardiac surgery is narrated from early extra cardiac procedures to open heart surgery. The Italian author, Dr. Tesler, has been a testimonial of any step...

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Cardiopulmonary Bypass Suppresses Forkhead Box O3 and Downstream Autophagy in the Diabetic Human Heart

Abstract Background Autophagy is an integral component of cellular  and metabolism. The exact mechanism of impaired autophagy in diabetes mellitus is unknown. Forkhead Box O3 (FOXO3α) is a key regulator of..

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Balancing the Blood Component Transfusion Ratio for High- and Ultra High–Dose Cell Salvage Cases

Abstract Objective To assess the ratio of non-red blood cell to red blood cell components required to avoid coagulopathy when transfusing large amounts of salvaged blood using laboratory test–guided therapy...

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Collateral flow at circle of Willis in healthy condition

Abstract Experimental simulation of cerebrovascular system would be very beneficial tool to evaluate millions of human body cascade sequence. The Circle of Willis (CoW) recently named Cerebral Arterial Circle (CAC)..

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Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries

Abstract Importance  Tracheal intubation is one of the most commonly performed and high-risk interventions in critically ill patients. Limited information is available on adverse peri-intubation events. Objective  To evaluate the incidence and..

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Respiratory and Hemodynamic Effects of Prophylactic Alveolar Recruitment During Liver Transplant: A Randomized Controlled Trial.

Abstract Objectives Prolonged surgical retraction may cause atelectasis. We aimed to recruit collapsed alveoli, stepwise, monitored by lung dynamic compliance and observe effects on arterial oxygenation and systemic and graft..

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Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review

Abstract Background:  The mortality of critically ill patients with COVID-19 is high, particularly among those receiving mechanical ventilation (MV). Despite the high number of patients treated worldwide, data on respiratory..

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Venoarterial Extracorporeal Membrane Oxygenation for Postcardiotomy Shock—Analysis of the Extracorporeal Life Support Organization Registry

Abstract Objectives:  Refractory postcardiotomy cardiogenic shock complicating cardiac surgery yields nearly 100% mortality when untreated. Use of venoarterial extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock has increased worldwide recently. The aim of the current..

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The Use of Extracorporeal Circulation in Suspected Brain Dead Organ Donors with Cardiopulmonary Collapse

Abstract Background: Monitoring oxygen delivery to the oxygenator of a heart lung machine (HLM) is typically accomplished with an O2 analyzer connected to the gas inflow line. It is assumed when..

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Intraoperative crystalloid utilization variability and association with postoperative outcomes: A post hoc analysis of two multicenter prospective cohort studies

Abstract Background The optimal regimen for intravenous administration of intraoperative fluids remains unclear. Our goal was to analyze intraoperative crystalloid volume administration practices and their association with postoperative outcomes. Methods..

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Practical Considerations and Outcomes of Inter-facility ECMO Transfer of COVID-19 Patients During a Pandemic: The Mayo Clinic Experience

Abstract Inter-facility transport of a critically ill patient with Acute Respiratory Distress Syndrome (ARDS) may be necessary for a higher level of care and/or initiation of extracorporeal membrane oxygenation (ECMO)...

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International SOS completes first multiple ICU COVID-19 patient evacuation

Abstract A team of travel risk management experts from International SOS have completed a complex evacuation and repatriation involving four ICU COVID-19 patients from La Réunion to Paris. Commissioned by..

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Evidence mounts for ECMO in patients with severe COVID-19 respiratory failure

Abstract Two recently published studies report success with extracorporeal membrane oxygenation support in patients with acute respiratory distress syndrome associated with COVID-19. In a retrospective cohort study published in The Lancet Respiratory..

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All that glitters is not gold: an unusual presentation of S. aureus sepsis during ECMO

Abstract A 53-year-old male was submitted to veno-venous extracorporeal membrane oxygenation (ECMO) due to coronavirus disease 2019 (COVID-19) pneumonia for 84 days, without relevant complications related to the circuit itself until..

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Cardiopulmonary bypass: development of John Gibbon's heart-lung machine

Abstract Objective: To provide a brief review of the development of cardiopulmonary bypass. Methods: A review of the literature on the development of extracorporeal circulation techniques, their essential role in..

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Hemoadsorption with CytoSorb in Septic Shock Reduces Catecholamine Requirements and In-Hospital Mortality: A Single-Center Retrospective ‘Genetic’ Matched Analysis

Abstract Septic shock is a major burden to healthcare with mortality rates remaining high. Blood purification techniques aim to reduce cytokine levels and resultant organ failure. Regarding septic shock, hemoadsorption..

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Minimally Invasive Right Ventricular Assist Device Implantation in a Patient with HeartWare left ventricular Assist Device

Abstract Many centers reported positive outcome after left ventricular assist devices (LVADs) implantation using a minimally invasive approach. The main drawback of this minimally invasive approach is the feasibility of..

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El COVID-19 en las Cardiopatías Congénitas

La pandemia del covid 19 ha impactado enormemente en nuestras vidas, cambiando modelos sociales, económicos y sanitarios. La información es desbordante, cambiante, instantánea, catastrófica unas veces, anecdótica otras, muchas veces..

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Less Invasive Left Ventricular Assist Device Implantation: One Right Step Toward the Future

Abstract The field of left ventricular assist devices (LVADs) witnessed an important boost after the introduction of the third-generation durable mechanical circulatory support devices. Among the technical improvements which contributed..

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Electrostatic Discharge Causing Pump Shutdown in HeartMate 3

Abstract  (LVADs) improve symptoms and outcomes in advanced heart failure. Although device malfunction has decreased significantly with later generation LVADs, it has not been eliminated. We describe the clinical course..

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