Mots clés Les archives: ischemia–reperfusion injury

Perfusfind S.L.

Introduction Cardiopulmonary bypass (CPB) is a life-saving technology used in cardiac surgery; however, it triggers a systemic inflammatory response (SIRS) due to blood contact with non-endothelial surfaces, ischemia-reperfusion injury, and..

Perfusfind S.L.

Abstract Chen et al. used a rat model of cardiopulmonary bypass followed by 30-min ischemia (induced by ascending aorta blockage) and 15-min reperfusion []. They reported that pyruvate dehydrogenase E1α..

Perfusfind S.L.

Abstract Introduction Critically ill patients supported with venoarterial  (VA ECMO) are at risk of developing severe arterial , which has been associated with increased mortality. Lower saturation targets in this population may..

Perfusfind S.L.

Abstract Although surgical techniques and perioperative care have made significant advances, perioperative mortality in cardiac surgery remains relatively high. Single- or multiple-organ failure remains the leading cause of postoperative mortality...

Perfusfind S.L.

Abstract In the United States, about one million people are seen to visit the operating theater for cardiac surgery annually. However, nearly half of these visits result in complications such..

Perfusfind S.L.

Abstract Cardiac reperfusion injury is a well-established outcome following treatment of acute myocardial infarction and other types of ischemic heart conditions. Numerous cardioprotection protocols and therapies have been pursued with..

Perfusfind S.L.

Abstract Background: Mitochondrial permeability transition pore (mPTP) opening plays a crucial role in cell death during ischemia-reperfusion injury (IRI). Cyclosporine A (CsA) inhibits mPTP opening. This study aimed to investigate..

Perfusfind S.L.

Abstract The protective effects of preprocedural esmolol on myocardial injury and hemodynamics have not, to date, been investigated in patients who were scheduled for cardiac surgeries under a cardiopulmonary bypass..

Perfusfind S.L.

Abstract Objective  induces  in the small . One reason for this damage is a perfusion shift from the muscular toward the mucosal layer. This study investigated the effect of this perfusion shift..

Perfusfind S.L.

Abstract Objectives The aim of this pilot study was to elucidate the effects of exogenous  (NO) supply to the  circuit for cardioprotection against  during  (CABG) with  (CPB). Methods A total of 60 patients with  scheduled for..