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Bicaval dual-lumen cannula for venovenous extracorporeal membrane oxygenation: Avalon© cannula in childhood disease

Abstract Severe acute refractory respiratory failure is considered a life-threatening situation, with a high mortality of 40 to 60%. When conservative oxygenation methods fail, a lifesaving measure is the introduction..

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Extracorporeal cytokine adsorption reduces systemic cytokine storm and improves graft function in lung transplantation

Abstract Objectives Ischemia–reperfusion injury often coincides with a , which can result in  following . Our previous research has demonstrated  improvement by cytokine adsorption during ex vivo lung perfusion. The aim of this study was..

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Impact of the Pediatric ABO Policy Change on Listings, Transplants, and Outcomes for Children Younger Than 2 Years Listed for…

Abstract Background: We assessed the impact of the liberalized ABO pediatric policy change on candidate characteristics and outcomes for children undergoing heart transplant (HT). Methods and results: Children <2 years undergoing HT..

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Nonischemic Donor Heart Preservation: New Milestone in Heart Transplantation History

Abstract Heart transplantation is considered the gold standard for the treatment of advanced end-stage heart failure. However, standard donors after brain death are decreasing, whereas patients on the heart transplant waitlist are..

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Contemporary practice and perception of autologous blood salvage in hepato-pancreatico-biliary operations: an international survey

Abstract Background This study aimed to assess contemporary knowledge, attitudes and behaviors around transfusion of intraoperative salvaged blood (sRBCt) during hepato-pancreatico-biliary (HPB) operations. Findings are meant to inform the design..

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Predictors of early mobilization in patients requiring VV ECMO for greater than 7 days: An international cohort study

Abstract Background Despite the demonstrated benefits of rehabilitation, active physical therapy and early mobilization are not universally performed during critical illness, especially among patients receiving extracorporeal membrane oxygenation (ECMO), with..

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Modifications to therapeutic plasma exchange to achieve rapid exchange on cardiopulmonary bypass prior to pediatric cardiac transplant

Abstract Background Cardiac transplants increasingly occur following placement of ventricular assist devices (VADs). A strong association exists between human leukocyte antigen (HLA) sensitization and VAD placement; however, desensitization protocols that..

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The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation

Abstract Objective The use of mechanical circulatory support (MCS) in lung transplantation has been steadily increasing over the prior decade, with evolving strategies for incorporating support in the preoperative, intraoperative,..

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Swine intestinal segment perfusion model for the evaluation of nutrients bioaccessibility

Abstract Nutrition science requires more science-based evidences for the development of effective functional diets. To reduce animals for experimental purposes innovative reliable and informative models, simulating the complex intestinal physiology,..

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A report of the first pediatric heart transplant following donation after circulatory death in the United States using ex-vivo perfusion

Abstract Cardiac donation after circulatory death (DCD) with ex-vivo perfusion (EVP) has the potential to greatly increase the donor pool, a benefit that can extend to selected pediatric patients. We..

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Partial Heart Transplantation in Adult Cardiac Surgery

Abstract Many young adults require heart valve replacements. Current options for valve replacement in adults include mechanical valves, bioprosthetic valves, or the Ross procedure. Of these, mechanical and bioprosthetic valves..

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The Future of heart procurement with donation after circulatory death: Current practice and opportunities for advancement

Abstract Heart Donation after Circulatory Death (DCD) has the potential to significantly increase the number of patients benefitting from . However, the expansion of DCD  is currently limited by unanswered questions pertaining..

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Venovenous extracorporeal membrane oxygenation promotes alveolar epithelial recovery by activating Hippo/YAP signaling after lung injury

Abstract Background The preferred configuration for bridging patients with respiratory failure while awaiting  is venovenous  (VV ECMO). However, the protective effect of VV ECMO on the lung, as well as the underlying..

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New horizons for reduction of blood use: Patient blood management

Abstract A countrywide study over the eras indicates overuse of blood transfusion can have considerable risks to patients accompanied by significant costs of blood transfusion for patients, hospitals, and health-care..

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VA-ECMO Cardiac Support During Liver Transplant: A Case Report

Abstract Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for cardiovascular collapse during and after liver transplantation (LT). According to the most recent guidelines, patients with severe cardiomyopathy are excluded..

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Additional Extracorporeal Membrane Oxygenation Pump Without an Oxygenator for Transseptal Left Atrial Decompression: A Case Report

Abstract A 63-year-old man developed chest pain and dyspnea. Venoarterial-venous extracorporeal membrane oxygenation (ECMO) was applied to the patient due to failing heart after percutaneous coronary intervention. We used an..

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Elective and non-elective endomyocardial biopsy in heart transplant patients and procedural outcomes: An IMPACT registry analysis

Abstract Background Endomyocardial biopsies are standard of care for transplant surveillance, however the procedural risks are not well established, especially in children. The purpose of the study was therefore to..

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Ex-situ oxygenated hypothermic machine perfusion in donation after circulatory death heart transplantation following either direct procurement or in-situ normothermic regional…

Abstract Background Heart transplantation in donation after circulatory death (DCD) relies on warm perfusion using either in situ normothermic regional perfusion (NRP) or ex situ normothermic machine perfusion. In this..

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Extracorporeal membrane oxygenation in adults receiving haematopoietic cell transplantation: an international expert statement

Abstract Combined advances in haematopoietic cell transplantation (HCT) and intensive care management have improved the survival of patients with haematological malignancies admitted to the intensive care unit. In cases of..

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PROTOCOLO NACIONAL DE TRASPLANTE CARDíACO INFANTIL AB0 INCOMPATIBLE

Abstract La práctica del trasplante AB0 incompatible (AB0i) surgió en el Hospital Sick Children de Toronto (Canadá) bajo el liderazgo de la Doctora Lori J. West, cardióloga e inmunóloga pediátrica..

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Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review

Abstract A growing body of evidence supports the use of extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) refractory to maximal medical therapy. ARDS may develop in..

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Extracorporeal Membrane Oxygenation in Acute Respiratory Failure

Abstract Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is a form of mechanical life support that provides full respiratory bypass in patients with severe respiratory failure as a bridge to recovery..

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Surgical Science and the Evolution of Critical Care Medicine

Abstract Surgical science has driven innovation and inquiry across adult and pediatric disciplines that provide critical care regardless of location. Surgically originated but broadly applicable knowledge has been globally shared..

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Planned Extracorporeal Life Support Employment during Liver Transplantation: The Potential of ECMO and CRRT as Preventive Therapies—Case Reports and Literature…

Abstract Liver Transplantation (LT) has become the gold standard treatment for End-Stage Liver Disease (ESLD). One of the main strategies to manage life-threatening complications, such as cardio-respiratory failure, is Extracorporeal..

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Rapid desensitization through immunoadsorption during cardiopulmonary bypass. A novel method to facilitate human leukocyte antigen incompatible heart transplantation

Abstract Background Anti-human leukocyte antigen (HLA)-antibody production represents a major barrier to heart transplantation, limiting recipient compatibility with potential donors and increasing the risk of complications with poor waiting-list outcomes...

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Diagnostic and Therapeutic Implications of Ex Vivo Lung Perfusion in Lung Transplantation: Potential Benefits and Inherent Limitations

Abstract Ex vivo lung perfusion (EVLP), a technique in which isolated lungs are continually ventilated and perfused at normothermic temperature, is emerging as a promising platform to optimize donor lung..

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Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome

Abstract Background Reliable biomarkers for organ quality assessment during normothermic machine perfusion (NMP) are desired. ATP (adenosine triphosphate) production by oxidative phosphorylation plays a crucial role in the bioenergetic homeostasis..

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Effect of Autotransfusion in HCC Surgery on Survival and Recurrence: A Systematic Review and Meta-Analysis

Abstract Background: The chronic blood shortage has forced clinicians to seek alternatives to allogeneic blood transfusions during surgery. Due to anatomic uniqueness resulting in a vast vasculature, liver surgery can..

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Patterns of Use in Transesophageal Echocardiography for Liver Transplantation: A Systematic Review

Abstract Transesophageal echocardiography is frequently but not always used to guide anesthetic management during liver transplantation. We performed a systematic review of the literature to identify and summarize any studies..

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