Tags Archives: Acute kidney injury (AKI)

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Urinary hypoxia: an intraoperative marker of risk of cardiac surgery-associated acute kidney injury

Abstract Background Acute kidney injury (AKI) is common after cardiac surgery and profoundly affects postoperative mortality and morbidity. There are no validated methods to assess risk of AKI intraoperatively. Methods..

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Pre‐operative anaemia, intra‐operative hepcidin concentration and acute kidney injury after cardiac surgery: a retrospective observational study

Abstract Acute kidney after cardiac surgery is more common in anaemic patients, whereas haemolysis during cardiopulmonary bypass may lead to iron‐induced renal injury. Hepcidin promotes iron sequestration by macrophages: hepcidin..

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The level of urinary IL-18 in acute kidney injury after cardiopulmonary bypass

ABSTRACT This study investigated the diagnostic value of urinary interleukin-18 (uIL-18) in acute kidney injury (AKI) after cardiopulmonary bypass (CPB) in clinical practice. A total of 103 patients who underwent..

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Reference change values of plasma and urine NGAL in cardiac surgery with cardiopulmonary bypass

Abstract Objective As with any biomarker, interpretation of changes of  concentration must consider its variability in a specific clinical setting. The aim of this study was to calculate the reference change..

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Red Blood Cell Exosome Hemoglobin Content Increases After Cardiopulmonary Bypass and Mediates Acute Kidney Injury in an Animal Model

Abstract Objective Hemolysis, characterized by formation of free hemoglobin (Hb), occurs in patients undergoing cardiopulmonary bypass (CPB). However, there is no study of the dynamic changes in red blood cell..

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Risk Assessment of Acute Kidney Injury Following Cardiopulmonary Bypass

Abstract Background Acute kidney injury (AKI) is a frequent and serious complication of cardiac surgery, associated with a high incidence of morbidity and mortality. Although the RIFLE criteria serve as..

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A Review on Extracorporeal Membrane Oxygenation and Kidney Injury

Abstract Extracorporeal membrane oxygenation (ECMO) is inevitable external life support in case of cardiac and respiratory failure since the 1970s. Acute kidney injury (AKI) and the requirement of renal replacement..

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Association Between Intraoperative Hyperoxia and Acute Kidney Injury After Cardiac Surgery: A Retrospective Observational Study

Abstract Objective Optimal oxygen management during cardiac surgery has not been established, and studies on the effects of perioperative hyperoxia on postoperative acute kidney injury (AKI) are scarce. The association..

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Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury

Abstract Objective Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) serves to hemoconcentrate blood volume to avoid allogeneic blood transfusions. Previous studies have determined CUF volumes as a continuous variable are..

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Goal-Directed Perfusion to Reduce Acute Kidney Injury after Paediatric Cardiac Surgery (GDP-Akip): Study Protocol for A Prospective Randomised Controlled Trial

Abstract Introduction Cardiac surgery-associated acute kidney injury (CS-AKI) occurs in up to 40%~60% of paediatric patients and increases postoperative morbidity and mortality. A goal-directed perfusion (GDP) strategy aimed at maintaining..

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