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Bleeding and thrombosis associated with ventricular assist device therapy

Abstract Over the past decade, continuous-flow rotary pumps have dramatically improved survival for patients with advanced . Bleeding and thrombosis, however, continue to be the Achilles heel of  (LVAD) therapy. There is..

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2016 survey about temperature management during extracorporeal circulation in China

Abstract Objective: In order to assess the current status of temperature management during cardiopulmonary bypass (CPB) in China and, thereby, implement standardized management protocols, the authors carried out a national..

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New Technology Mimics Physiologic Pulsatile Flow During Cardiopulmonary Bypass

Abstract The VentriFlo True Pulse Pump (Design Mentor, Inc., Pelham, NH, USA) is the first blood pump designed to mimic human arterial waveforms in a standard oxygenation circuit. Our aim was..

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Cerebral Microhemorrhage: A Frequent Magnetic Resonance Imaging Finding in Pediatric Patients after Cardiopulmonary Bypass

Abstract Objectives: This study was undertaken to estimate the incidence and burden of cerebral microhemorrhage (CM) in patients with heart disease who underwent cardiopulmonary bypass (CPB), as detected on susceptibility-weighted..

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Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass

Abstract Purpose Cardiopulmonary bypass (CPB) induces a significant inflammatory response that may increase the risk for delirium. We hypothesized that exposure to CPB during coronary artery bypass grafting (CABG) surgery..

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A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension

Abstract During cardiac operations, weaning from cardiopulmonary bypass (CPB) may prove challenging as a result of superimposed acute right ventricular dysfunction in the setting of elevated pulmonary vascular resistance (PVR)...

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Prophylactic Fibrinogen Decreases Postoperative Bleeding but Not Acute Kidney Injury in Patients Undergoing Heart Transplantation

Abstract The present study is the premier clinical attempt to scrutinize the practicability of prophylactic fibrinogen infusion in patients undergoing heart transplantation (HT). A total of 67 consecutive patients who..

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Haem is associated with thrombosis in neonates and infants undergoing cardiac surgery for congenital heart disease

Abstract Background Haem levels are associated with thrombosis in a variety of diseases, as well as being a contributing cause of thrombotic events in animal models. Materials and Methods We..

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Assessing the depth of isoflurane anaesthesia during cardiopulmonary bypass

Abstract Introduction: Bispectral index (BIS) and monitoring of end-tidal concentration may be associated with a reduction in the incidence of awareness during volatile-based general anaesthesia. An analogue of end-tidal concentration..

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Influence of high-flow modified ultrafiltration on brain oxygenation and perfusion during surgery for children with ventricular septal defects: a pilot…

Abstract Background: Modified ultrafiltration (MUF) can be performed in infants with ventricular septal defects (VSDs) after cardiopulmonary bypass (CPB) to reduce haemodilution and its potential adverse effects. High-flow MUF might..

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Prevalence and Overtesting of True Heparin-Induced Thrombocytopenia in a 591-Bed Tertiary Care, Teaching Hospital

Abstract Heparin-induced thrombocytopenia type II (HIT) is a rare but potentially fatal antibody-mediated reaction to all forms of heparin (unfractionated heparin, low-molecular weight heparin, heparin flushes, and heparin-coated catheters), which..

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Normothermic Cardiopulmonary Bypass in Patient With Waldenström’s Macroglobulinemia and Cryoglobulinemia: A Case Report

Abstract Waldenström’s macroglobulinemia (WM) manifests as hyperviscosity syndrome. Cryoglobulinemia, which may increase blood viscosity or induce thrombosis in association with decreased body temperature, can occur in combination with WM. We..

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Brain-Dead Donors on Extracorporeal Membrane Oxygenation

Abstract Objectives:  To describe donors after brain death with ongoing extracorporeal membrane oxygenation and to analyze the outcome of organs transplanted from these donors. Design:  Retrospective analysis of the national..

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Pediatric Extracorporeal Membrane Oxygenation

Extracorporeal life support (ECLS), commonly referred to as extracorporeal membrane oxygenation (ECMO), is a modified form of cardiopulmonary bypass. Venous blood is drained from the patient and advanced to a..

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Empirical Vancomycin Dosing in Pediatric Patients with Congenital Heart Disease and the Impact of Cardiopulmonary Bypass on Trough Concentrations

Abstract Objectives To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and to examine the impact of cardiopulmonary bypass..

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Practice meta-environment of the cardiovascular perfusionist

Abstract Though historically the development of cardiovascular perfusion grew out of the need for cardiopulmonary bypass, the application of technologies of extracorporeal support has more recently expanded beyond the traditional..

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Differentiating between cold agglutinins and rouleaux: a case series of seven patients

Abstract We present a case series of seven patients with suspected cold agglutinin antibodies, discovered after initiation of bypass. Laboratory analysis of blood samples intraoperatively determined the cause of the..

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Operative strategies to reduce cerebral embolic events during on- and off-pump coronary artery bypass surgery: A stratified, prospective randomized trial

Abstract Objective To determine the impact of different  strategies on the incidence of cerebral embolic events during  (CABG). Methods Between 2012 and 2015, 142 patients with low-grade  (epiaortic ultrasound grade I/II) undergoing primary..

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The neurologic protection of unilateral versus bilateral antegrade cerebral perfusion in aortic arch surgery with deep hypothermic circulatory arrest: A…

Abstract Backgroud Unilateral and bilateral antegrade  (ACP) are recognized methods of cerebral protection in . However, the adequacy of cerebral protection in aortic arch surgery with  is controversial. In this study, we compared..

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Efficacy and safety of inhaled anaesthetic for postoperative sedation during mechanical ventilation in adult cardiac surgery patients: a systematic review…

Abstract The aim was to evaluate the efficacy and safety of volatile anaesthetic for postoperative sedation in adult cardiac surgery patients through a systematic review and meta-analysis. We retrieved randomized..

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Long-term survival and quality of life after extracorporeal life support: a 10-year report

Abstract OBJECTIVES:  Information is lacking about long-term survival and quality of life (QOL) after treating patients on extracorporeal life support. METHODS:  Outcome data were assessed by phone interviews, a QOL..

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Pneumonia after cardiac surgery: Experience of the National Institutes of Health/Canadian Institutes of Health Research Cardiothoracic Surgical Trials Network

Abstract Rationale Pneumonia remains the most common major infection after cardiac surgery despite numerous preventive measures. Objectives To prospectively examine the timing, pathogens, and risk factors, including modifiable management practices,..

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Antithrombin III is associated with acute liver failure in patients with end-stage heart failure undergoing mechanical circulatory support

Abstract Objective There are few data on the role of  in patients with end-stage heart failure supported by mechanical . The aim of our study was to investigate predictors for  in patients with..

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Thirty-Year Mortality After Coronary Artery Bypass Graft Surgery

Abstract Background Data are sparse on long-term mortality after coronary artery bypass graft (CABG) surgery. We examined short-term and long-term mortality of patients undergoing CABG surgery and a general population..

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Monitoring the quality of cardiac surgery based on three or more surgical outcomes using a new variable life-adjusted display

Abstract Quality problem or issue The traditional variable life-adjusted display (VLAD) is a graphical display of the difference between expected and actual cumulative deaths. The VLAD assumes binary outcomes: death..

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Air in intravenous lines: a need to review old opinions

Abstract At the time of writing this editorial, I have been in health care for exactly 45 years. These years have taken me through many challenging settings, including intensive cares,..

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Development and Evaluation of Heartbeat: A Machine Perfusion Heart Preservation System

Abstract Static cold storage is accompanied with a partial safe ischemic interval for donor hearts. In this current study, a machine perfusion system was built to provide a better preservation..

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Use of CytoSorb in a patient with septic shock in the context of mastitis and gangrenous cholecystitis

This report describes the case of a 63-year-old female patient, who was admitted to the Intensive Care Unit with the diagnosis of septic shock. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/03/caso-semana-cyto_compressed.pdf" title="caso semana cyto_compressed"]

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Neuroprotective effect of pressure-oriented flow regulation and pH-stat management in selective antegrade brain perfusion during total aortic arch repair

Abstract OBJECTIVES The aim of this study was to assess the safety and effectiveness of our selective antegrade brain perfusion (SABP) strategy, which is characterized by moderate hypothermic and low-pressure..

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